Afuco™ Anti-SELP ADCC Recombinant Antibody (Crizanlizumab), ADCC Enhanced (CAT#: AFC-TAB-015ML)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to SELP. Crizanlizumab is a human monoclonal antibody that can be potentially used in the treatment of Sickle Cell Disease (SCD).
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2145/5903_A_9_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2145/5903_A_9_3.jpg
Figure 2 RNA cell line category: Group enriched (EFO-21, HEL)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
Figure 2 RNA cell line category: Group enriched (EFO-21, HEL)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000174175-SELP
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Specificity
- Human SELP
- Species Reactivity
- Human
- Clone
- Crizanlizumab
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Crizanlizumab
- Related Disease
- Sickle Cell Disease (SCD)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Crizanlizumab"
Anti-Human SELP Recombinant Antibody (Crizanlizumab)Recombinant monoclonal antibody to SELP. Crizanlizumab is a human monoclonal antibody that can be potentially used in the treatment of Sickle Cell Disease (SCD).
See other products for "SELP"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-985 | Recombinant Mouse Anti-Human SELP Antibody F(ab')2 Fragment, clone G1/G1-4 | FC, FX | F(ab')2 |
| HPAB-AP436-YC-F(E) | Human Anti-SELP Recombinant Antibody (clone HuMab 005); Fab Fragment | ELISA | Human Fab |
| HPAB-AP437-YC-F(E) | Human Anti-SELP Recombinant Antibody (clone HuMab 010I); Fab Fragment | ELISA | Human Fab |
| HPAB-AP438-YC-F(E) | Human Anti-SELP Recombinant Antibody (clone HuMab 011); Fab Fragment | ELISA | Human Fab |
| HPAB-AP439-YC-F(E) | Human Anti-SELP Recombinant Antibody (clone HuMab 017); Fab Fragment | ELISA | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-246 | Anti-Human selectin P Recombinant Antibody (Inclacumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - kappa |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-263CT | Mouse Anti-SELP Recombinant Antibody (TAB-263CT) | Inhib, FC | Mouse IgG |
| TAB-263CT-S(P) | Mouse Anti-SELP Recombinant Antibody; scFv Fragment (TAB-263CT-S(P)) | WB, ELISA | Mouse scFv |
| TAB-263CT-F(E) | Mouse Anti-SELP Recombinant Antibody; Fab Fragment (TAB-263CT-F(E)) | WB, ELISA | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-264CT | Humanized Anti-SELP Recombinant Antibody (TAB-264CT) | WB, ELISA | Humanized antibody |
| TAB-264CT-S(P) | Humanized Anti-SELP Recombinant Antibody; scFv Fragment (TAB-264CT-S(P)) | WB, ELISA | Humanized scFv |
| TAB-264CT-F(E) | Humanized Anti-SELP Recombinant Antibody; Fab Fragment (TAB-264CT-F(E)) | WB, ELISA | Humanized Fab |
| TAB-015ML | Anti-Human SELP Recombinant Antibody (Crizanlizumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1933CQ | Recombinant Mouse Anti-SELP Antibody (AK4) | WB, IP, FuncS, ICC, FC, BL | IgG1 |
| NEUT-1934CQ | Recombinant Mouse Anti-Selp Antibody (RMP-1) | FC, IF, IHC, ELISA, WB, IP, BL | IgG2a, κ |
| NEUT-1936CQ | Recombinant Mouse Anti-SELP Antibody (VMC207) | BL, IHC | IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1935CQ | Recombinant Mouse Anti-Selp Antibody (Psel.KO2.12) | FC, FuncS, Neut | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3203 | Hi-Affi™ Recombinant Rabbit Anti-SELP Monoclonal Antibody (DS3203AB) | WB, IHC-P | IgG |
| MOR-4550 | Hi-Affi™ Recombinant Rabbit Anti-SELP Monoclonal Antibody (TH60DS) | WB, IF, ICC, FC, ELISA | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0257-YC | Mouse Anti-SELP Recombinant Antibody (clone 5C7.29) | FC, Block | Mouse IgG |
| HPAB-0258-YC | Human Anti-SELP Recombinant Antibody (clone hu5C7.29) | FC, Block | Humanized IgG |
| HPAB-0259-YC | Mouse Anti-SELP Recombinant Antibody (clone PB1.3) | ELISA, Block | Mouse IgG |
| HPAB-0260-YC | Human Anti-SELP Recombinant Antibody (clone huPB1.3) | ELISA | Humanized IgG, κ |
| HPAB-J0222-YC | Human Anti-SELP Recombinant Antibody (clone AP023/YC) | ELISA, WB, FuncS | Human IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-246 | Afuco™ Anti-SELP ADCC Recombinant Antibody (Inclacumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP431-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 001); scFv Fragment | ELISA | Human scFv |
| HPAB-AP432-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 002); scFv Fragment | ELISA | Human scFv |
| HPAB-AP433-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 002 IgG4v1); scFv Fragment | ELISA | Human scFv |
| HPAB-AP434-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 003); scFv Fragment | ELISA | Human scFv |
| HPAB-AP435-YC-S(P) | Human Anti-SELP Recombinant Antibody (clone HuMab 004I); scFv Fragment | ELISA | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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