Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP443-YC-F(E))

Name: Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP443-YC-F(E))
SKU: HPAB-AP443-YC-F(E)
Rating: 5 (1 reviews)

CAT#: HPAB-AP443-YC-F(E)

This product is a recombinant human antibody Fab fragment that recognizes SEMA4D. The antibody was purified by affinity chromatography.

Gene Expression

Normal Tissue Figure 1 IHC staining of human skeletal muscle

Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23277/ihc_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15662/37983_B_8_5.jpg

Normal Tissue Figure 3 Colon

Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15662/37983_A_7_3.jpg

Normal Tissue Figure 4 Liver

Cholangiocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15662/37983_A_7_4.jpg

Normal Tissue Figure 5 Kidney

Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15662/37983_A_7_5.jpg

Normal Tissue Figure 6 Testis

Leydig cells Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15662/37983_A_6_6.jpg

Normal Tissue Figure 7 Lymph node

Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15662/37983_A_9_8.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (HDLM-2, HMC-1, JURKAT, MOLT-4)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000187764-SEMA4D

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Specifications

Host Species
Human

Type
Human Fab

Specificity
Human SEMA4D

Species Reactivity
Human

Applications
ELISA, FC, Block

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
See the COA

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Semaphorin 4D; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Short Cytoplasmic Domain, (Semaphorin) 4D; C9orf164; SEMAJ; CD100; BB18; GR3; A8; Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) And Short Cytoplasmic Domain, 4D

Gene ID
10507

UniProt ID
Q92854

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-AP443-YC-F(E).pdf

MSDS

MSDS - HPAB-AP443-YC-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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HPAB-AP440-YC	Mouse Anti-SEMA4D Recombinant Antibody (HPAB-AP440-YC)	ELISA, Block, Neut, FuncS	Mouse IgG2b
HPAB-AP442-YC	Mouse Anti-SEMA4D Recombinant Antibody (HPAB-AP442-YC)	ELISA, Block, Neut, FuncS	Mouse IgG2b
HPAB-AP443-YC	Human Anti-SEMA4D Recombinant Antibody (HPAB-AP443-YC)	ELISA, FC, Block	Human IgG1
HPAB-AP444-YC	Human Anti-SEMA4D Recombinant Antibody (HPAB-AP444-YC)	ELISA, FC, Block	Human IgG1
HPAB-AP445-YC	Human Anti-SEMA4D Recombinant Antibody (HPAB-AP445-YC)	ELISA, Block	Human IgG1

CAT	Product Name	Application	Type
HPAB-AP440-YC-F(E)	Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP440-YC-F(E))	ELISA, Block, Neut, FuncS	Mouse Fab
HPAB-AP442-YC-F(E)	Mouse Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP442-YC-F(E))	ELISA, Block, Neut, FuncS	Mouse Fab
HPAB-AP444-YC-F(E)	Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP444-YC-F(E))	ELISA, FC, Block	Human Fab
HPAB-AP445-YC-F(E)	Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP445-YC-F(E))	ELISA, Block	Human Fab
HPAB-AP446-YC-F(E)	Human Anti-SEMA4D Recombinant Antibody; Fab Fragment (HPAB-AP446-YC-F(E))	ELISA, Block	Human Fab

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