Mouse Anti-STAT6 Monoclonal Antibody (VS7-0425-WR930)
CAT#: VS7-0425-WR930
This product is a mouse IgG antibody that binds to human STAT6. The antibody can be used for WB, IF, ICC, and ELISA assays. It cross reacts with mouse, rat, and monkey.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1861/27_A4_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human urinary bladder
Immunohistochemical staining of human urinary bladder shows strong cytoplasmic and nuclear positivity in urothelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1861/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1861/7497_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1861/7497_A_7_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1861/7497_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1861/7497_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1861/7497_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166888-STAT6/subcellular
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Specifications
- Immunogen
- Recombinant human STAT6 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human STAT6
- Species Reactivity
- Human, Mouse, Rat, Monkey
- Molecule Class
- STAT (Signal Transducers And Activators Of Transcription) Protein
- Applications
- WB, IF, ICC, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Hyper-IgE syndrome 6, autosomal dominant, with recurrent infections (HIES6)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunofluorescence: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- STAT6B; STAT6C; D12S1644; IL-4-STAT
- Gene ID
- 6778
- UniProt ID
- P42226
- Long Name
- Signal transducer and activator of transcription 6
- Cellular Localization
- Cytoplasm; Nucleus
- Post Translation Modifications
- Acetylation; ADP-ribosylation; Phosphoprotein
- Protein Refseq
- NP_001171549.1
- Function
- Activator; DNA-binding
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Related Diseases
Endometrial Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
Throid Cancer
Related Signaling Pathways
MAPK Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "STAT6"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0567MZ | Chicken Anti-STAT6 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3430 | Hi-Affi™ Recombinant Rabbit Anti-STAT6 Monoclonal Antibody (DS3430AB) | FC, ICC, IP, WB | IgG |
| MOR-4713 | Hi-Affi™ Recombinant Rabbit Anti-STAT6 Monoclonal Antibody (TH227DS) | WB, IF, ICC, IHC-P, FC, ChIP, ELISA | IgG |
| MOR-4745 | Hi-Affi™ Recombinant Rabbit Anti-STAT6 Monoclonal Antibody (TH259DS) | WB, IF, ICC, IHC-P, FC, ChIP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1443-CN | Recombinant Rabbit Anti-STAT6 Monoclonal Antibody (CBACN-534) | WB, IF, IHC, IP | Rabbit IgG |
| MRO-1444-CN | Recombinant Rabbit Anti-STAT6 Monoclonal Antibody (CBACN-535) | WB, IF, IHC, IP | Rabbit IgG |
| MRO-2202-CN | Rabbit Anti-STAT6 Polyclonal Antibody (MRO-2202-CN) | WB, IF, IHC, FC | Rabbit IgG |
| ZG-118R | Mouse Anti-STAT6 Recombinant Antibody (ZG-118R) | WB, ELISA, IF | Mouse IgG |
| VS7-0425-WR929 | Mouse Anti-STAT6 Monoclonal Antibody (clone 7D3) | WB, ICC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC633 | AbPlus™ Anti-STAT6 Magnetic Beads (VS-0724-YC633) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2198 | Anti-STAT6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6961 | Anti-Mouse STAT6 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6960 | Anti-Human STAT6 Immunohistochemistry Kit | IHC |
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