AbPlus™ Anti-TFPI Magnetic Beads (VS-0724-YC647)
CAT#: VS-0724-YC647
The AbPlus Anti-TFPI Magnetic Beads (VS-0724-YC647) is an innovative affinity resin which is bound with anti-TFPI specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of TFPI protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human smooth muscle
Immunohistochemical staining of human smooth muscle shows distinct positivity in endothelial.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5575/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows distinct cytoplasmic positivity in endothelium.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endocrine cells Staining: High Intensity: Strong Endothelial cells Staining: High Intensity: Strong Quantity:>75% Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25% Peripheral nerve/ganglion Staining: Low Intensity: Weak
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_7_3.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_4_6.jpg
Normal Tissue
Figure 6 Placenta
Decidual cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/20842/46624_A_2_7.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HHSteC, HUVEC TERT2, LHCN-M2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000003436-TFPI
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-TFPI specific antibody
- Target
- TFPI
- Immunogen
- Recombinant human TFPI/LACI, aa 1-282.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
- Alternative Names
- Tissue Factor Pathway Inhibitor; Extrinsic Pathway Inhibitor; Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor); TFPI1; LACI; EPI; Lipoprotein-Associated Coagulation Inhibitor; Anti-Convertin; TFI;
- Gene ID
- 7035
- UniProt ID
- P10646
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "TFPI"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-734 | Anti-TFPI Recombinant Antibody (Concizumab) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG4 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2015CT | Recombinant Mouse anti-Human TFPI Monoclonal antibody (5H5) | ELISA, WB | |
| HPAB-0476-CN | Mouse Anti-TFPI Recombinant Antibody (HPAB-0476-CN) | ELISA | Mouse IgG |
| HPAB-0477-CN | Human Anti-TFPI Recombinant Antibody (HPAB-0477-CN) | ELISA, Neut | Chimeric (mouse/human) IgG1, κ |
| HPAB-0478-CN | Human Anti-TFPI Recombinant Antibody (HPAB-0478-CN) | ELISA, Neut | Humanized IgG1, κ |
| HPAB-0479-CN | Human Anti-TFPI Recombinant Antibody (HPAB-0479-CN) | ELISA, Neut | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3547 | Rabbit Anti-TFPI Recombinant Antibody (clone DS3547AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0476-CN-S(P) | Mouse Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0476-CN-S(P)) | ELISA | Mouse scFv |
| HPAB-0477-CN-S(P) | Mouse Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0477-CN-S(P)) | ELISA, Neut | Mouse scFv |
| HPAB-0478-CN-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0478-CN-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0479-CN-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0479-CN-S(P)) | ELISA, Neut | Human scFv |
| HPAB-0480-CN-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0480-CN-S(P)) | ELISA, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0429-YC-F(E) | Human Anti-TFPI Recombinant Antibody (clone TFPI-118); Fab Fragment | ELISA, FC, FuncS | Human Fab |
| HPAB-0431-YC-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-0431-YC-F(E)) | ELISA, FC | Human Fab |
| PFBC-539 | Human Anti-TFPI Recombinant Antibody (clone ch2F22); Fab Fragment | ELISA, FC, Neut | Chimeric (mouse/human) Fab |
| HPAB-2587LY-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-2587LY-F(E)) | ELISA, WB, FuncS | Human Fab |
| HPAB-2588LY-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-2588LY-F(E)) | ELISA, WB, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-734 | Afuco™ Anti-TFPI ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-734) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY189 | Human Anti-TFPI (clone Concizumab) scFv-Fc Chimera | ELISA, FC | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7198 | Anti-TFPI Immunohistochemistry Kit | IHC |
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