What applications can this antibody be used for?

This mouse anti-TFRC recombinant antibody, specifically the scFv Fragment, can be used primarily in ELISA. Its specificity for the transferrin receptor makes it useful in studies focusing on iron metabolism and the cellular uptake of iron.

What is the significance of targeting TFRC?

TFRC, or transferrin receptor, is key in cellular iron uptake through transferrin binding and endocytosis. Understanding TFRC interactions can help in studies related to cancer, as many tumor cells show high transferrin receptor expression, making it a focus in cancer research.

Does the antibody come with any conjugation options?

While the base product comes unconjugated, Creative Biolabs offers options for various conjugations like PE, APC, Biotin, FITC, and HRP, allowing flexibility for different assay needs.

Mouse Anti-TFRC Recombinant Antibody (clone OX26); scFv Fragment

CAT#: FAMAB-0281-YC-S(P)

The OX26 murine monoclonal antibody scFv Fragment to the rat tansferrin receptor binds an exofacial epitope on this receptor.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to endosomes & lysosomes.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28598/546_F8_1_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/207_B2_1_blue_red_green.jpg

Subcellular Location Figure 3 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/208_B2_1_blue_red_green.jpg

Normal Tissue Figure 4 Cerebral cortex

Endothelial cells
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_B_9_5.jpg

Normal Tissue Figure 5 Colon

Glandular cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_8_3.jpg

Normal Tissue Figure 6 Testis

Leydig cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Pachytene spermatocytes
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_6_6.jpg

Normal Tissue Figure 7 Bone marrow

Hematopoietic cells
Staining:

High

Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_B_6_4.jpg

Normal Tissue Figure 8 Lymph node

Germinal center cells
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_8_8.jpg

RNA Expression Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)

Cell lines ordered by descending RNA expression order.

RNA Expression Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000072274-TFRC

❮

❯

Specifications

Host Species
Mouse

Type
Mouse scFv

Specificity
Rat TFRC

Species Reactivity
Rat

Clone
OX26

Applications
ELISA

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Trfr

Gene ID
64678

UniProt ID
G3V679

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for FAMAB-0281-YC-S(P). Click the button above to contact us or submit your feedback about this product.

Breast cancer biomarkers at key points during disease progression

Great for Iron Metabolism Studies

We have been using this antibody in our ongoing research on iron metabolism. Its specificity towards the transferrin receptor offered us clear insights into iron uptake processes, helping us develop more refined models for our studies.

Dependable Research Tool

The scFv fragment of the Mouse Anti-TFRC Antibody has been a reliable addition to our lab's toolbox. It showed precise results in our ELISA tests targeting the transferrin receptor. Easy to store and handle, definitely a great asset for our biochemical studies.

Q&As

What applications can this antibody be used for?

A: This mouse anti-TFRC recombinant antibody, specifically the scFv Fragment, can be used primarily in ELISA. Its specificity for the transferrin receptor makes it useful in studies focusing on iron metabolism and the cellular uptake of iron.
What is the significance of targeting TFRC?

A: TFRC, or transferrin receptor, is key in cellular iron uptake through transferrin binding and endocytosis. Understanding TFRC interactions can help in studies related to cancer, as many tumor cells show high transferrin receptor expression, making it a focus in cancer research.
Does the antibody come with any conjugation options?

A: While the base product comes unconjugated, Creative Biolabs offers options for various conjugations like PE, APC, Biotin, FITC, and HRP, allowing flexibility for different assay needs.

View the frequently asked questions answered by Creative Biolabs Support.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - FAMAB-0281-YC-S(P).pdf

MSDS

MSDS - FAMAB-0281-YC-S(P).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "Clone OX26"

CAT
Product Name

See other products for "TFRC"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-1176z	Mouse Anti-TFRC Recombinant Antibody (MOB-1176z)	ELISA, WB, IP, IF, IHC, FC	Mouse IgG1, κ
HPAB-0376-CN	Mouse Anti-TFRC Recombinant Antibody (HPAB-0376-CN)	ELISA, FC	Mouse IgG
HPAB-0377-CN	Mouse Anti-TFRC Recombinant Antibody (HPAB-0377-CN)	ELISA, FC	Mouse IgG
HPAB-0378-CN	Mouse Anti-TFRC Recombinant Antibody (HPAB-0378-CN)	ELISA, FC	Mouse IgG
HPAB-0379-CN	Human Anti-TFRC Recombinant Antibody (HPAB-0379-CN)	ELISA, FC	Humanized IgG

CAT	Product Name	Application	Type
MOB-1176z-F(E)	Recombinant Anti-Human TFRC Antibody Fab Fragment	WB, Neut, FuncS	Fab
HPAB-0376-CN-F(E)	Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0376-CN-F(E))	ELISA, FC	Mouse Fab
HPAB-0377-CN-F(E)	Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0377-CN-F(E))	ELISA, FC	Mouse Fab
HPAB-0378-CN-F(E)	Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0378-CN-F(E))	ELISA, FC	Mouse Fab
HPAB-0379-CN-F(E)	Human Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0379-CN-F(E))	ELISA, FC	Humanized Fab

CAT	Product Name	Application	Type
MOB-1176z-S(P)	Recombinant Anti-Human TFRC Antibody scFv Fragment	ELISA, WB, IF, FuncS	scFv
HPAB-0376-CN-S(P)	Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-0376-CN-S(P))	ELISA, FC	Mouse scFv
HPAB-0377-CN-S(P)	Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-0377-CN-S(P))	ELISA, FC	Mouse scFv
HPAB-0378-CN-S(P)	Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-0378-CN-S(P))	ELISA, FC	Mouse scFv
HPAB-0379-CN-S(P)	Human Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-0379-CN-S(P))	ELISA, FC	Humanized scFv

CAT	Product Name	Application
AGTO-G067E	Anti-TFRC immunotoxin HB21 (scFv)-PE	Cytotoxicity assay, Function study
AGTO-G067D	Anti-TFRC immunotoxin HB21 (scFv)-DT	Cytotoxicity assay, Function study
AGTO-G067G	Anti-TFRC immunotoxin HB21 (scFv)-Gel	Cytotoxicity assay, Function study
AGTO-G067R	Anti-TFRC immunotoxin HB21 (scFv)-RTA	Cytotoxicity assay, Function study
AGTO-G067S	Anti-TFRC immunotoxin HB21 (scFv)-Sap	Cytotoxicity assay, Function study

CAT	Product Name	Application	Type
TAB-615CT	Anti-Human TfR Recombinant Antibody (6-90)	ELISA, WB, IP

CAT	Product Name	Application
TAB-616CT	Anti-Human TfR Recombinant Antibody (55-31)	ELISA, WB, IP
TAB-617CT	Anti-Human TfR Recombinant Antibody (122-72)	ELISA, WB, IP
TAB-618CT	Anti-Human TfR Recombinant Antibody (5D7-54.17)	ELISA, WB, IP
TAB-615CT-S(P)	Anti-Human TfR Recombinant Antibody scFv Fragment (6-90)	ELISA, WB, IP
TAB-616CT-S(P)	Anti-Human TfR Recombinant Antibody scFv Fragment (55-31)	ELISA, WB, IP

CAT	Product Name	Application	Type
TAB-611CT-S(P)	Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-611CT-S(P))	ELISA	Humanized scFv
TAB-612CT-S(P)	Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-612CT-S(P))	ELISA	Humanized scFv
TAB-613CT-S(P)	Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-613CT-S(P))	ELISA	Humanized scFv
TAB-614CT-S(P)	Humanized Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-614CT-S(P))	ELISA	Humanized scFv
TAB-611CT-F(E)	Humanized Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-611CT-F(E))	ELISA	Humanized Fab

CAT	Product Name	Application	Type
TAB-619CT-F(E)	Human Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-619CT-F(E))	ELISA, WB	Human Fab
TAB-620CT-F(E)	Human Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-620CT-F(E))	ELISA, WB	Human Fab
TAB-621CT-F(E)	Anti-Human TfR Recombinant Antibody Fab Fragment (LUCA31)	ELISA, WB, FC	Human antibody
TAB-623CT-F(E)	Anti-Human TfR Recombinant Antibody Fab Fragment (3TF12)	WB	Human antibody
TAB-624CT-F(E)	Anti-Human TfR Recombinant Antibody Fab Fragment (3TF2)	WB	Human antibody

CAT	Product Name	Application	Type
NEUT-1999CQ	Rat Anti-Tfrc Recombinant Antibody (clone RI7217)	FC, ICC, IP, WB, Block	Rat IgG2a, κ

CAT	Product Name	Application	Type
MOR-3548	Rabbit Anti-TFRC Recombinant Antibody (clone DS3548AB)	FC, IP, WB	Rabbit IgG

CAT	Product Name	Application	Type
MHC-LC3370	PE-DRB1*13:02/Human TFRC (NPGGYVAYSKAATVTGKL) MHC Tetramer	FCM
MHC-LC3371	PE-DRB1*13:02/Human TFRC (NPGGYVAYSKAATVTG) MHC Tetramer	FCM

CAT	Product Name	Application	Type
VS-0724-YC1481	AbPlus™ Anti-TFRC Magnetic Beads (VS-0724-YC1481)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0225-XY205	CytoStream™ Mouse Anti-TFRC Recombinant Antibody (clone OX-26)	FC, IHC, IP	Mouse IgG2a, kappa
VS-0225-XY206	CytoStream™ Rat Anti-TFRC Recombinant Antibody (clone RI7217)	FC	Rat IgG2a, kappa

CAT	Product Name	Application	Type
VS-0425-YC571	Recombinant Anti-TFRC Vesicular Antibody, EV Displayed (VS-0425-YC571)	ELISA, FC, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-XY7200	Anti-Mouse TFRC Immunohistochemistry Kit	IHC
VS-0525-XY7201	Anti-Rat TFRC Immunohistochemistry Kit	IHC

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 2 Anti-Human IGF1R Antibody (TAB-199) in WB

Human Anti-IGF1R Recombinant Antibody (TAB-199) (CAT# TAB-199)
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC

Figure 3 Anti-VEGFR-1 Recombinant Antibody (TAB-177) in DB

Anti-Human VEGFR-1 Recombinant Antibody (TAB-177) (CAT# TAB-177)
Application: IF, IP, Neut, FuncS, ELISA, FC, WB

Figure 9 Anti-Human BAFF Recombinant Antibody in ELISA

Anti-Human BAFF Recombinant Antibody (TAB-216) (CAT# TAB-216)
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC

Figure 2 Anti-Human Met (TAB-190-F(E)) in ELISA

Anti-Human Met(Onartuzumab) (CAT# TAB-190-F(E))
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

Figure 3 Anti-ERBB3 Recombinant Antibody (TAB-892) in DB

Anti-Human ERBB3/ErbB 3 Recombinant Antibody (Seribantumab) (CAT# TAB-892)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 3 Anti-ErbB2 Antibody (TAB-053) in Dot Blot

Anti-Human ERBB2 Recombinant Antibody (TAB-053) (CAT# TAB-053)
Application: FuncS, IF, Neut, ELISA, FC, IP, WB

Figure 6 Anti-Human VEGF Recombinant Antibody (TAB-011) in ELISA

Anti-Human VEGF Recombinant Antibody (Bevacizumab) (CAT# TAB-011)
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC

Figure 2 Human CD27 Recombinant Antibody (TAB-H74) in HPLC

Human Anti-Human CD27 Recombinant Antibody (TAB-H74) (CAT# TAB-H74)
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC

Figure 3 Anti-CD40 Antibody (TAB-126CL) in Dot Blot

Human Anti-CD40 Recombinant Antibody (TAB-126CL) (CAT# TAB-126CL)
Application: Block, Cyt, FuncS, Inhib

Figure 1 Anti-Human ENG Recombinant Antibody (TAB-232CL) in SDS-PAGE

Anti-Human ENG Recombinant Antibody (TAB-232CL) (CAT# TAB-232CL)
Application:

Figure 2 Mouse Anti-EREG Recombinant Antibody (PABL-084) in HPLC

Mouse Anti-EREG Recombinant Antibody (clone 9E5) (CAT# PABL-084)
Application: ELISA, WB, FuncS

Figure 3 Anti-RABV G Recombinant Antibody (MRO-730LC) in WB

Anti-RABV G Recombinant Antibody (MRO-730LC) (CAT# MRO-730LC)
Application: ELISA, Neut, WB

Figure 1 Mouse Anti-ROR1 Recombinant Antibody (HPAB-0308-CN) in SDS-PAGE

Mouse Anti-ROR1 Recombinant Antibody (HPAB-0308-CN) (CAT# HPAB-0308-CN)
Application: ELISA, FC

Figure 3 Anti-CD40 Antibody in (MOB-120CQ) Dot Blot

Human Anti-CD40 Recombinant Antibody (MOB-120CQ) (CAT# MOB-120CQ)
Application: ELISA, IHC, IF, IP, FC, FuncS

Figure 4 Anti-SIRPA Recombinant Antibody (NS-080CN) in ELISA

Human Anti-SIRPA Recombinant Antibody (clone 29-AM3-35) (CAT# NS-080CN)
Application: ELISA, Inhib, FuncS

Figure 3 Anti-MAPT Recombinant Antibody (NS-090CN) in ELISA

Mouse Anti-MAPT Recombinant Antibody (NS-090CN) (CAT# NS-090CN)
Application: WB, ELISA, IHC, IP, SPR, FuncS

Figure 2 Recombinant Mouse Anti-CD22 Antibody (HPAB-N0324-YC) in HPLC

Mouse Anti-CD22 Recombinant Antibody (HPAB-N0324-YC) (CAT# HPAB-N0324-YC)
Application: FuncS

Figure 7 Anti-EBV gH/gL Antibody (PABC-419) in ELISA

Recombinant Mouse Anti-EBV gH/gL Antibody (CL40) (CAT# PABC-419)
Application: ELISA, Inhib, FC, Neut

Figure 2 Human Anti-FRβ Recombinant Antibody (m909) (HPAB-0792-FY) in ELISA.

Human Anti-FRβ Recombinant Antibody (HPAB-0792-FY) (CAT# HPAB-0792-FY)
Application: ELISA

Figure 3 Anti-TPO Recombinant Antibody (FAMAB-0014JF) in DB

Human Anti-TPO Recombinant Antibody (clone B8) (CAT# FAMAB-0014JF)
Application: WB, ELISA, IHC

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.