Rat Anti-Mouse Tgfbr1 Recombinant Antibody (VS-0224-XY93), PE (CAT#: VS-0224-XY93)
The product is a rat monoclonal antibody which recognizes mouse transforming growth factor, beta receptor I (Tgfbr1). It was purified by protein A or G affinity chromatography. This product has been determined by Enzyme-linked immunosorbent assay, Western blot and Flow cytometry.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/56473/985_F7_2_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/56473/985_F7_2_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows distinct cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2441/ihc_selected.jpg
(Immunohistochemical staining of human tonsil shows distinct cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2441/ihc_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_B_9_5.jpg
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_B_9_5.jpg
Figure 4 Cerebellum
(Cells in granular layer Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Purkinje cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_B_8_8.jpg
(Cells in granular layer Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Purkinje cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_B_8_8.jpg
Figure 5 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_A_7_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_A_7_3.jpg
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31481/66574_A_8_5.jpg
Figure 7 RNA cell line category: Cell line enhanced (RH-30)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106799-TGFBR1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000106799-TGFBR1
Specifications
- Immunogen
- S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Tgfbr1 extracellular domain (Ala21-Glu121).
- Host Species
- Rat
- Type
- Rat IgG2a
- Specificity
- Mouse Tgfbr1
- Species Reactivity
- Mouse
- Applications
- ELISA, Western Blot, Flow Cytometry
- Conjugate
- PE
- Related Disease
- Multiple Self-Healing Squamous Epithelioma; Loeys-Dietz Syndrome 1
Product Property
- Purification
- Protein A or G purified
- Buffer
- A saline solution containing BSA
- Preservative
- Sodium Azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested in Flow cytometry (10 µL/106 cells).
Target
- Alternative Names
- ALK5; ESK2; Alk-5; TGFR-1; TbetaRI; AU017191; TbetaR-I
- Gene ID
- 21812
- UniProt ID
- Q64729
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Related Resources
JAK-STAT Signaling Pathway
TGF-β Signaling Pathway
Pancreatic Cancer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TGFBR1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4032z | Mouse Anti-TGFBR1 Recombinant Antibody (clone 43H12) | WB, ELISA, IHC | Mouse IgG1 |
| MOB-2021CT | Recombinant Mouse anti-Human TGFBR1 Monoclonal antibody (9B22) | IHC-P | |
| ZG-0114C | Mouse Anti-TGFBR1 Recombinant Antibody (clone ABT-TGFR1) | IHC-P, IF | Mouse IgG |
| ZG-0115C | Mouse Anti-TGFBR1 Recombinant Antibody (clone ABT-TGFR2) | IHC-P, IF | Mouse IgG |
| VS3-CJ919 | Mouse Anti-TGFBR1 Recombinant Antibody (VS3-CJ919) | IHC | Mouse IgG2a |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L077E | TGFα-PE immunotoxin | Cytotoxicity assay, Functional assay |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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