Mouse Anti-THY1 Recombinant Antibody (clone OX7) (CAT#: FAMAB-1301CQ)

This product is a recombinant mouse antibody that recognizes THY1. The antibody was purified by affinity chromatography. It can be used in WB, IHC.


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IHC

Figure 1 Histology of anti-Thy1.1 nephritis at day 9.

Figure 1 Histology of anti-Thy1.1 nephritis at day 9.

Amelioration of features by the use of MMF-loaded OX7-IL is shown. Formalin-fixed, methacrylate-embed-ded tissue specimens and toluidine blue staining were used. Magnification, ×60.

Suana, A. J., Tuffin, G., Frey, B. M., Knudsen, L., Mühlfeld, C., Rödder, S., & Marti, H. P. (2011). Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. Journal of pharmacology and experimental therapeutics, 337(2), 411-422.

IF

Figure 2 Immunofluorescence staining for collagen IV and fibronectin in anti-Thy1.1 nephritis at day 9.

Figure 2 Immunofluorescence staining for collagen IV and fibronectin in anti-Thy1.1 nephritis at day 9.

Nephritic animals treated with MMF-loaded OX7-IL show faint staining of fibronectin. Formalin-fixed paraffin-embedded tissue specimens were used. Magnification, 60×.

Suana, A. J., Tuffin, G., Frey, B. M., Knudsen, L., Mühlfeld, C., Rödder, S., & Marti, H. P. (2011). Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. Journal of pharmacology and experimental therapeutics, 337(2), 411-422.

Cyt

Figure 3 Cytotoxicity of MMF-OX7-IL was assessed by in situ end-labeling of DNA fragments.

Figure 3 Cytotoxicity of MMF-OX7-IL was assessed by in situ end-labeling of DNA fragments.

Cell nuclei of nephritic animals treated with MMF-loaded OX7-IL.

Suana, A. J., Tuffin, G., Frey, B. M., Knudsen, L., Mühlfeld, C., Rödder, S., & Marti, H. P. (2011). Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. Journal of pharmacology and experimental therapeutics, 337(2), 411-422.

IHC

Figure 4 Immunohistostaining for α-SMA in anti-Thy1.1 nephritis at day 9.

Figure 4 Immunohistostaining for α-SMA in anti-Thy1.1 nephritis at day 9.

Amelio-ration of these features in nephritic animals treated with MMF-loaded OX7-IL is shown.

Suana, A. J., Tuffin, G., Frey, B. M., Knudsen, L., Mühlfeld, C., Rödder, S., & Marti, H. P. (2011). Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. Journal of pharmacology and experimental therapeutics, 337(2), 411-422.


Specifications

  • Immunogen
  • Rat Thy- 1L+ antigen in complete Freund's adjuvant
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Rat CD90
  • Species Reactivity
  • Mouse, Rat
  • Clone
  • OX7
  • Applications
  • IHC, IF, Cyt

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Immunofluorescence, Immunohistochemistry and Cytotoxicity.

Target

  • Alternative Names
  • Thy-1 Cell Surface Antigen; Thy-1 Antigen; CDw90; Thy-1 Membrane Glycoprotein; Thy-1 T-Cell Antigen; CD90 Antigen; CD90;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone OX7"

See other products for "THY1"

Fab Fragment Antibody

CAT Product Name Application Type
MOB-1495z-F(E) Recombinant Anti-Human THY1 Antibody Fab Fragment FC, WB, FuncS Fab

Immunotoxin

CAT Product Name Application Type
AGTO-G060R Anti-THY1 immunotoxin OX7 (F (ab')2)-RTA Cytotoxicity assay, Function study
AGTO-G060S Anti-THY1 immunotoxin OX7 (F (ab')2)-Sap Cytotoxicity assay, Function study
AGTO-L040R anti-THY1 immunotoxin AT15E (IgG)-RTA Cytotoxicity assay, Functional assay
AGTO-L040S anti-THY1 immunotoxin AT15E (IgG)-Sap Cytotoxicity assay, Functional assay
AGTO-L060S anti-Thy1 immunotoxin OX7 (IgG)-Sap Cytotoxicity assay, Functional assay

Blocking Antibody

CAT Product Name Application Type
NEUT-2023CQ Rat Anti-THY1 Recombinant Antibody (clone YKIX337.217) Block, FC Rat IgG2b

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3568 Rabbit Anti-THY1 Recombinant Antibody (clone DS3568AB) ICC, IHC-P, WB Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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