Human Anti-TPO Recombinant Antibody (clone WR1.7) (CAT#: FAMAB-1281CQ)
This product is a recombinant human antibody that recognizes TPO. The antibody was purified by affinity chromatography. It can be used in Competition, RIA, FC.
Specific Inquiry
ELISA
Figure 1 Binding of anti-TPO antibodies (human Fabs, rabbit antipeptides, and mouse mAbs) to human TPO.
ELISA experiments were performedby coating human TPO at 1μg/ml.
Bresson, D., Rebuffat, S. A., Nguyen, B., Banga, J. P., Gardas, A., & Peraldi-Roux, S. (2005). New insights into the conformational dominant epitopes on thyroid peroxidase recognized by human autoantibodies. Endocrinology, 146(6), 2834-2844.
Inhib
Figure 2 Inhibition of human Fabs bind-ing to TPO by rabbit polyclonal anti-peptide antibodies.
The binding of hu-man anti-TPO-specific Fab WR1.7 were inhibited by rabbit antipeptide anti-bodies (P1, P12, P14, P18, P24, P43,P50, P760-779, and S10).
Bresson, D., Rebuffat, S. A., Nguyen, B., Banga, J. P., Gardas, A., & Peraldi-Roux, S. (2005). New insights into the conformational dominant epitopes on thyroid peroxidase recognized by human autoantibodies. Endocrinology, 146(6), 2834-2844.
Specifications
- Host Species
- Human
- Type
- Human IgE
- Specificity
- TPO
- Species Reactivity
- Human
- Clone
- WR1.7
- Applications
- ELISA, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Inhibition and Enzyme-Linked Immunosorbent Assay.
Target
- Alternative Names
- Thyroid Peroxidase; EC 1.11.1.8; Thyroid Microsomal Antigen; Thyroperoxidase; EC 1.11.1; TDH2A; MSA; TPX
- Gene ID
- 7173
- UniProt ID
- P07202
Related Resources
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone WR1.7"
See other products for "TPO"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-999-S(P) | Recombinant Anti-TPO Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| MHH-999-S(P) | Recombinant Human Anti-TPO Antibody scFv Fragment | WB, FC, FuncS | scFv |
| PSBW-123 | Human Anti-TPO Recombinant Antibody (clone TR1.9); scFv Fragment | WB, ELISA | Human scFv |
| HPAB-2017-FY-S(P) | Human Anti-TPO Recombinant Antibody (clone FY-019); scFv Fragment | ELISA | Human scFv |
| FAMAB-0042JF-S(P) | Human Anti-TPO Recombinant Antibody (clone ICA5); scFv Fragment | WB, ELISA, FuncS | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-999-F(E) | Recombinant Human Anti-TPO Antibody Fab Fragment | IP, IF, FuncS | Fab |
| PFBW-123 | Human Anti-TPO Recombinant Antibody (clone TR1.9); Fab Fragment | WB, ELISA | Human Fab |
| FAMAB-0013JF-F(E) | Human Anti-TPO Recombinant Antibody (clone A12); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0014JF-F(E) | Human Anti-TPO Recombinant Antibody (clone B8); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| FAMAB-0364JF-F(E) | Human Anti-TPO Recombinant Antibody (clone RI-34); Fab Fragment | ELISA, FuncS | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABW-123 | Human Anti-TPO Recombinant Antibody (clone TR1.9) | Inhib | Human IgG |
| FAMAB-0364JF | Human Anti-TPO Recombinant Antibody (clone RI-34) | ELISA, FuncS | Human IgG |
| ZG-0120C | Mouse Anti-TPO Recombinant Antibody (clone ABT-TPO) | IHC-P, IF | Mouse IgG |
| ZG-0121C | Mouse Anti-TPO Recombinant Antibody (clone PT0857) | WB | Mouse IgG |
| VS3-FY1477 | Recombinant Mouse Anti-TPO Antibody (clone 9G3-6F3-9B7) | IHC-P | Mouse IgG2b |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2215CQ | Mouse Anti-TPO Recombinant Antibody (clone CBL296) | Neut, ELISA | Mouse IgG2b |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3658 | Rabbit Anti-TPO Recombinant Antibody (clone DS3658AB) | IHC-P, IP, WB | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC4548 | PE-DQB1*03:02/Human TPO (IDVWLGGLAENFLP) MHC Tetramer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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