Recombinant Anti-CD59 Vesicular Antibody, EV Displayed (VS-0425-YC183)
CAT#: VS-0425-YC183
The Recombinant Anti-CD59 Vesicular Antibody, EV Displayed (VS-0425-YC183) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD59-expressed cells or tissues. The CD59 is a protein involved in complement binding and is associated with diseases like hemolytic anemia. It participates in pathways including the creation of C4 and C2 activators and transport to the Golgi and modification.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/279_B8_2_selected.jpg
Subcellular Location
Figure 2 IHC staining of human urinary bladder
Immunohistochemical staining of human urinary bladder shows distinct membranous positivity in urothelial cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/ihc_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to the vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/1432_F1_2_blue_red_green.jpg
Subcellular Location
Figure 4 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/280_B8_1_blue_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/55053_B_8_5.jpg
Normal Tissue
Figure 6 Colon
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/55159_A_7_3.jpg
Normal Tissue
Figure 7 Urinary bladder
Urothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/55159_A_6_5.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (TIME, U-2197)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000085063-CD59
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD59
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD59 molecule (CD59 blood group)
- Cellular Localization
- Golgi apparatus, Vesicles
- Introduction
- CD59 (CD59 Molecule (CD59 Blood Group)) is a Protein Coding gene. Diseases associated with CD59 include Hemolytic Anemia, Cd59-Mediated, With Or Without Immune-Mediated Polyneuropathy and Hemolytic Anemia. Among its related pathways are Creation of C4 and C2 activators and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include complement binding.
- Alternative Names
- 16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20
- Gene ID
- 966
- UniProt ID
- P13987
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "CD59"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1088z | Mouse Anti-CD59 Recombinant Antibody (clone 18C6) | FC, IF, FuncS | Mouse IgM, κ |
| MOB-0520CT | Recombinant Mouse anti-Human CD59 Monoclonal antibody (2G6) | FC | |
| MRO-0311-CN | Rabbit Anti-CD59 Recombinant Antibody (clone JM10-71) | WB, IF, FC, IP | Rabbit IgG |
| ZG-0208U | Mouse Anti-CD59 Recombinant Antibody (clone 2E11B6) | ELISA, WB, IHC | Mouse IgG1 |
| VS3-WK768 | Mouse Anti-CD59 Recombinant Antibody (clone OV9A2) | FC, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-317LC | Mouse Anti-CD59 Recombinant Antibody (TAB-317LC) | WB, ELISA | Mouse IgG1 |
| TAB-318LC | Anti-Human CD59 Recombinant Antibody (1E8) | ELISA, FC | |
| TAB-320LC | Anti-Human CD59 Recombinant Antibody (AR36A36.11.1) | ELISA, WB, FC | |
| TAB-317LC-S(P) | Mouse Anti-CD59 Recombinant Antibody; scFv Fragment (TAB-317LC-S(P)) | WB, ELISA | Mouse scFv |
| TAB-318LC-S(P) | Anti-Human CD59 Recombinant Antibody scFv Fragment (1E8) | FC, ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-319LC | Human Anti-CD59 Recombinant Antibody (TAB-319LC) | ELISA, FC, Inhib | Human IgG1 |
| TAB-319LC-S(P) | Human Anti-CD59 Recombinant Antibody; scFv Fragment (TAB-319LC-S(P)) | ELISA | Human scFv |
| TAB-319LC-F(E) | Human Anti-CD59 Recombinant Antibody; Fab Fragment (TAB-319LC-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-321LC | Anti-Human CD59 Recombinant Antibody ((ch)AR36A36.11.1) | ELISA, FuncS, WB | Chimeric antibody (mouse/human) |
| TAB-321LC-S(P) | Anti-Human CD59 Recombinant Antibody scFv Fragment ((ch)AR36A36.11.1) | WB, ELISA | Chimeric antibody (mouse/human) |
| TAB-321LC-F(E) | Anti-Human CD59 Recombinant Antibody Fab Fragment ((ch)AR36A36.11.1) | WB, ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-322LC | Anti-Human CD59 Recombinant Antibody (HV3/KV3 ) | Cyt, ELISA | Humanized antibody |
| TAB-323LC | Anti-Human CD59 Recombinant Antibody (HV2/KV3) | Cyt, ELISA | Humanized antibody |
| TAB-324LC | Anti-Human CD59 Recombinant Antibody (HV2/KV4) | Cyt, ELISA | Humanized antibody |
| TAB-322LC-S(P) | Anti-Human CD59 Recombinant Antibody scFv Fragment (HV3/KV3 ) | WB, ELISA | Humanized antibody |
| TAB-323LC-S(P) | Anti-Human CD59 Recombinant Antibody scFv Fragment (HV2/KV3) | WB, ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-397CQ | Mouse Anti-CD59 Recombinant Antibody (clone MEM-43) | Neut, FC, IHC, IHC-P, IP, CyTOF® | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-398CQ | Rat Anti-CD59 Recombinant Antibody (clone YTH53.1) | Block, FC, ICC, IF, IHC-Fr, IHC-P, WB, FuncS | Rat IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0572 | Hi-Affi™ Rabbit Anti-CD59 Recombinant Antibody (clone DS572AB) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1953 | PE-A2/Human CD59 (SLSEKTVLL) MHC Tetramer | FCM | |
| MHC-LC1980 | PE-A*02:01/Human CD59 (SLSEKTVLL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1325 | AbPlus™ Anti-Cd59 Magnetic Beads (VS-0724-YC1325) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY58 | Human Anti-CD59 (clone 1E8) scFv-Fc Chimera | ELISA, FC, CDC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY62 | CytoStream™ Mouse Anti-CD59 Recombinant Antibody (clone MEM-43) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY368 | Anti-CD59 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1204 | Anti-Mouse CD59 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1203 | Anti-Human CD59 Immunohistochemistry Kit | IHC |
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