This product is a monoclonal antibody against CD59. This is a humanized antibody that could potentially be used to treat prostate, breast and lung cancer. CD59 is an 18-20 kDa glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein expressed in a variety of normal and cancer tissues.
Figure 1 demonstrates the binding of humanized variants, chimeric and murine AR36A36.11.1 to the human breast cancer cell line MDA-MB-231.
Figure 2 demonstrates the in vitro CDC activity of murine and humanized variants of AR36 A36.11.1 on the human breast cancer cell line MD A-MB-231.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-317LC | Mouse Anti-CD59 Recombinant Antibody (TAB-317LC) | WB, ELISA | Mouse IgG1 |
TAB-318LC | Anti-Human CD59 Recombinant Antibody (1E8) | ELISA, FC | |
TAB-320LC | Anti-Human CD59 Recombinant Antibody (AR36A36.11.1) | ELISA, WB, FC | |
TAB-317LC-S(P) | Mouse Anti-CD59 Recombinant Antibody; scFv Fragment (TAB-317LC-S(P)) | WB, ELISA | Mouse scFv |
TAB-318LC-S(P) | Anti-Human CD59 Recombinant Antibody scFv Fragment (1E8) | FC, ELISA |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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