Mouse Anti-CD59 Recombinant Antibody (clone YTH 53.1) (CAT#: FAMAB-1074CQ)

This product is a recombinant mouse antibody that recognizes CD59. The antibody was purified by affinity chromatography. It can be used in FC.


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Figure 1 Enhancement of complement-mediated cell lysis by F(ab')2 fragments of YTH 53.1.

Figure 1 Enhancement of complement-mediated cell lysis by F(ab')2 fragments of YTH 53.1.

Each incubation contained 50 ul of F(ab')2 fragments (50 ug/ml) (●) or medium (○), 50 ul of partner antibody or medium (control), 50 ul of 51Cr-labeled cells, and 50 ul of complement.

Davies, A. L. E. X. A. N. D. R. A., Simmons, D. L., Hale, G., Harrison, R. A., Tighe, H., Lachmann, P. J., & Waldmann, H. (1989). CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. The Journal of experimental medicine, 170(3), 637-654.


Specifications

  • Immunogen
  • T lymphocytes in human PBMC
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • CD59
  • Species Reactivity
  • Human
  • Clone
  • YTH 53.1
  • Applications
  • FC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CD59 Molecule (CD59 Blood Group); CD59 Antigen P18-20 (Antigen Identified By Monoclonal Antibodies 16.3A5, EJ16, EJ30, EL32 And G344); CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; Membrane Inhibitor Of Reactive Lysis; 20 KDa Homologous Restriction Factor; MEM43 Antigen; 1F5 Antigen; Protectin; HRF-20; MAC-IP; MIC11; MSK21; HRF20; MACIF; MIN1; MIN2; MIN3; MIRL; Surface Anitgen Recognized By Monoclonal Antibody 16.3A5

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone YTH 53.1"

See other products for "CD59"

Chimeric Antibody

CAT Product Name Application Type
TAB-321LC Anti-Human CD59 Recombinant Antibody ((ch)AR36A36.11.1) ELISA, FuncS, WB Chimeric antibody (mouse/human)
TAB-321LC-S(P) Anti-Human CD59 Recombinant Antibody scFv Fragment ((ch)AR36A36.11.1) WB, ELISA Chimeric antibody (mouse/human)
TAB-321LC-F(E) Anti-Human CD59 Recombinant Antibody Fab Fragment ((ch)AR36A36.11.1) WB, ELISA Chimeric antibody (mouse/human)

Humanized Antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-397CQ Mouse Anti-CD59 Recombinant Antibody (clone MEM-43) Neut, FC, IHC, IHC-P, IP, CyTOF® Mouse IgG2a

Blocking Antibody

CAT Product Name Application Type
NEUT-398CQ Rat Anti-CD59 Recombinant Antibody (clone YTH53.1) Block, FC, ICC, IF, IHC-Fr, IHC-P, WB, FuncS Rat IgG2b

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0572 Hi-Affi™ Rabbit Anti-CD59 Recombinant Antibody (clone DS572AB) WB, IHC Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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