Recombinant Rabbit Anti-CSF1 Detection Antibody (clone R05-8L2) (CAT#: VS3-WK1749)
This antibody is a rabbit recombinant antibody against human CSF1. It was developed by immunization of rabbit with recombinant human CSF1 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R06-2G2 and R05-8L2 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R05-8L2 can be used in ELISA analysis to identify human CSF1.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1709_G12_12_cr5800dfbe06bb5_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1709_G12_12_cr5800dfbe06bb5_selected.jpg
Figure 2 IF staining of human cell line ASC TERT1
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1876_A10_31_blue_red_green.jpg
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1876_A10_31_blue_red_green.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear bodies.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1769_A4_33_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nuclear bodies.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76624/1769_A4_33_blue_red_green.jpg
Figure 4 RNA cell line category: Cell line enhanced (ASC diff, BJ hTERT+, GAMG, HHSteC, HSkMC, hTERT-RPE1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000184371-CSF1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000184371-CSF1
Specifications
- Immunogen
- Recombinant human CSF1 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CSF1
- Species Reactivity
- Human
- Clone
- R05-8L2
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Colony Stimulating Factor 1; Colony Stimulating Factor 1 (Macrophage); Macrophage Colony Stimulating Factor 1; Lanimostim; CSF-1; MCSF; Macrophage Colony-Stimulating Factor 1; M-CSF
- Gene ID
- 1435
- UniProt ID
- P09603
- Long Name
- Colony Stimulating Factor 1
- Cellular Localization
- Cell membrane, Membrane, Secreted
- Post Translation Modifications
- N-glycosylated.
- Protein Refseq
- NP_000748.3
- Function
- Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Recommended Products
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Isotype Control
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Related Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CSF1"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-245-S(P) | Recombinant Anti-human CSF1 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| HPAB-0150CQ-S(P) | Human Anti-CSF1 Recombinant Antibody; scFv Fragment (HPAB-0150CQ-S(P)) | ELISA, WB, FC, Inhib | Human scFv |
| HPAB-0151CQ-S(P) | Human Anti-CSF1 Recombinant Antibody; scFv Fragment (HPAB-0151CQ-S(P)) | ELISA, WB, FC, Inhib | Human scFv |
| HPAB-0110-WJ-S(P) | Human Anti-CSF1 Recombinant Antibody; scFv Fragment (HPAB-0110-WJ-S(P)) | ELISA, FC, WB | Human scFv |
| HPAB-0748-WJ-S(P) | Human Anti-CSF1 Recombinant Antibody (clone 88); scFv Fragment | ELISA, WB, FC | Human scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-187CL | Human Anti-CSF1 Recombinant Antibody (TAB-187CL) | ELISA | Human IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-501CQ | Mouse Anti-CSF1 Recombinant Antibody (clone 3V17) | Neut, WB | Mouse IgG2 |
| NEUT-502CQ | Mouse Anti-CSF1 Recombinant Antibody (clone CBL140) | Neut, WB | Mouse IgG2 |
| NEUT-503CQ | Mouse Anti-CSF1 Recombinant Antibody (clone CBL441) | WB, Neut | Mouse IgG2a |
| NEUT-505CQ | Rat Anti-Csf1 Recombinant Antibody (clone CBL205) | WB, Neut | Rat IgG2 |
| NEUT-506CQ | Rat Anti-Csf1 Recombinant Antibody (clone CBL535) | WB, Neut | Rat IgG2b |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-504CQ | Rat Anti-Csf1 Recombinant Antibody (clone 5A1) | Block | Rat IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0824 | Hi-Affi™ Rabbit Anti-CSF1 Recombinant Antibody (clone DS824AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-029ML | Anti-Human CSF1 Recombinant Antibody (Lacnotuzumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0532-CN-F(E) | Mouse Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0532-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0533-CN-F(E) | Mouse Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0533-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0534-CN-F(E) | Mouse Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0534-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0535-CN-F(E) | Human Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0535-CN-F(E)) | ELISA, FC, Neut | Humanized Fab |
| HPAB-0537-CN-F(E) | Human Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0537-CN-F(E)) | ELISA, FC | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0150CQ | Human Anti-CSF1 Recombinant Antibody (HPAB-0150CQ) | ELISA, WB, FC, Inhib, FuncS | Human IgG |
| HPAB-0151CQ | Human Anti-CSF1 Recombinant Antibody (HPAB-0151CQ) | ELISA, WB, FC, Inhib, FuncS | Human IgG |
| HPAB-0748-WJ | Human Anti-CSF1 Recombinant Antibody (clone 88) | ELISA, WB, FC | Human IgG |
| HPAB-0749-WJ | Human Anti-CSF1 Recombinant Antibody (clone 100) | ELISA, WB, FC | Human IgG |
| HPAB-0750-WJ | Human Anti-CSF1 Recombinant Antibody (clone 3.8.3) | ELISA, WB, FC | Human IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-029ML | Afuco™ Anti-CSF1 ADCC Recombinant Antibody (Lacnotuzumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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