Recombinant Anti-IL6R Vesicular Antibody, EV Displayed (VS-0425-YC677)
CAT#: VS-0425-YC677
The Recombinant Anti-IL6R Vesicular Antibody, EV Displayed (VS-0425-YC677) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to IL6R-expressed cells or tissues. IL6R is a subunit of the interleukin 6 receptor complex, important in immune response regulation, implicated in diseases like multiple myeloma and autoimmune disorders.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (THP-1, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160712-IL6R
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- IL6R
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Monkey
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Interleukin 6 receptor
- Molecular Function
- Receptor
- Introduction
- This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
- Alternative Names
- CD126, gp80, IL-1Ra, IL-6R, IL6RA
- Gene ID
- 3570
- UniProt ID
- P08887
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L080E | IL6-PE immunotoxin | Cytotoxicity assay, Functional assay | |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-245 | Human Anti-IL6R Recombinant Antibody Fab Fragment (PFBL-245) | WB, Neut, FuncS | Human Fab |
| HPAB-0251CQ-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (HPAB-0251CQ-F(E)) | ELISA, FC, Block | Human Fab |
| HPAB-0446-WJ-F(E) | Mouse Anti-IL6R Recombinant Antibody; Fab Fragment (HPAB-0446-WJ-F(E)) | ELISA | Mouse Fab |
| HPAB-0447-WJ-F(E) | Mouse Anti-IL6R Recombinant Antibody; Fab Fragment (HPAB-0447-WJ-F(E)) | ELISA | Mouse Fab |
| HPAB-0448-WJ-F(E) | Mouse Anti-IL6R Recombinant Antibody; Fab Fragment (HPAB-0448-WJ-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-690LC | Anti-human IL6R Recombinant Antibody (PM-1) (TAB-690LC) | ELISA | |
| TAB-694LC | Rabbit Anti-IL6R Recombinant Antibody (TAB-694LC) | ELISA | Rabbit IgG |
| TAB-695LC | Rabbit Anti-IL6R Recombinant Antibody (TAB-695LC) | ELISA | Rabbit IgG |
| TAB-690LC-S(P) | Anti-human IL6R scFv Fragment (PM-1) | ELISA | |
| TAB-694LC-S(P) | Rabbit Anti-IL6R Recombinant Antibody; scFv Fragment (TAB-694LC-S(P)) | ELISA | Rabbit scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-691LC | Human Anti-IL6R Recombinant Antibody (TAB-691LC) | ELISA | Humanized IgG2, κ |
| TAB-692LC | Anti-human IL6R Recombinant Antibody (TAB-692LC) | ELISA | Humanized antibody |
| TAB-696LC | Human Anti-IL6R Recombinant Antibody (TAB-696LC) | Block, ELISA, FC, Inhib | Humanized antibody |
| TAB-697LC | Human Anti-IL6R Recombinant Antibody (TAB-697LC) | ELISA | Humanized antibody |
| TAB-032ML | Anti-Human IL6R Recombinant Antibody (TAB-032ML) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1485CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL212) | FC, ELISA, Neut | Mouse IgG1, κ |
| NEUT-1486CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL261) | FC, Neut | Mouse IgG1 |
| NEUT-1487CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL279) | Neut, WB, ELISA, FC | Mouse IgG1 |
| NEUT-1489CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL425) | WB, FC, CyTOF, ELISA, Neut | Mouse IgG1 |
| NEUT-1491CQ | Mouse Anti-IL6R Recombinant Antibody (clone MM0409-6M30) | WB, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1488CQ | Mouse Anti-IL6R Recombinant Antibody (clone B-F19) | Block | Mouse IgG1 |
| NEUT-1490CQ | Mouse Anti-IL6R Recombinant Antibody (clone B-R6) | IHC-Fr, Inhib, FC, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0331-CN | Human Anti-IL6R Recombinant Antibody (HPAB-0331-CN) | ELISA, FC, Neut | Human IgG1, κ |
| HPAB-0332-CN | Human Anti-IL6R Recombinant Antibody (HPAB-0332-CN) | ELISA, FC, Block | Human IgG1, κ |
| HPAB-0333-CN | Human Anti-IL6R Recombinant Antibody (HPAB-0333-CN) | ELISA, FC, Block | Human IgG1, κ |
| HPAB-0034-WJ | Mouse Anti-IL6R Recombinant Antibody (clone 8C1D8B5) | ELISA, WB | Mouse IgG1 |
| HPAB-0165-YJ | Human Anti-IL6R Recombinant Antibody (HPAB-0165-YJ) | ELISA, Block, Inhib | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0331-CN-S(P) | Human Anti-IL6R Recombinant Antibody (HPAB-0331-CN-S(P)); scFv Fragment | ELISA, FC, Neut | Human scFv |
| HPAB-0332-CN-S(P) | Human Anti-IL6R Recombinant Antibody (HPAB-0332-CN-S(P)); scFv Fragment | ELISA, FC, Block | Human scFv |
| HPAB-0718-CN-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (HPAB-0718-CN-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0719-CN-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (HPAB-0719-CN-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0720-CN-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (HPAB-0720-CN-S(P)) | ELISA, Neut | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-026 | Afuco™ Anti-IL6R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-026) | ELISA, FC, IP, FuncS, IF, Neut, ICC | ADCC enhanced antibody |
| AFC-TAB-032ML | Afuco™ Anti-IL6R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-032ML) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-691LC | Afuco™ Anti-IL6R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-691LC) | ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY152 | AbPlus™ Anti-IL6R Magnetic Beads (B-R6) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY12 | Human Anti-IL6R scFv-Fc Chimera (VS-0325-FY12) | ELISA, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC585 | CytoStream™ Rabbit Anti-IL6R Recombinant Antibody (VS13-YC585) | WB, IHC-P, ICC, IF, FC, ELISA | Rabbit IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3539 | Anti-IL6R Immunohistochemistry Kit | IHC | |
| VS-0525-XY3540 | Anti-Mouse IL6R Immunohistochemistry Kit | IHC |
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