Recombinant Rabbit Anti-ITGA2B Antibody (clone R01-1C2) (CAT#: VS3-FY769)
This product is a recombinant rabbit antibody that recognizes ITGA2B. This antibody has been reported for use in Western Blot. The clone R01-1C2 is specific for human, rat ITGA2B. The antigen is synthetic peptide of human cd41.
Specific Inquiry
WB
Figure 1. Recombinant Rabbit Anti-ITGA2B Antibody (clone R01-1C2) in WB.
Western Blot analysis of CD41 in C6, Hela lysates using Integrin α IIb antibody.
Specifications
- Immunogen
- Synthetic peptide of human CD41.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Rat ITGA2B
- Species Reactivity
- Human, Rat
- Clone
- R01-1C2
- Applications
- Western Blot
- Conjugate
- Unconjugated
- MW
- Calculated MW: 113 kDa; Observed MW: 137 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Integrin Subunit Alpha 2b
- Gene ID
- 3674
- UniProt ID
- P08514
- Sequence Similarities
- Belongs to the integrin alpha chain family.
- Cellular Localization
- Membrane
- Protein Refseq
- NP_000410.2
- Function
- Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-015-F(E) | Anti-Human CD41 Recombinant Antibody Fab Fragment (Abciximab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | Fab - G1 - kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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