Recombinant Rabbit Anti-ITGA2B Antibody (clone R01-1C2)
CAT#: VS3-FY769
This product is a recombinant rabbit antibody that recognizes ITGA2B. This antibody has been reported for use in Western Blot. The clone R01-1C2 is specific for human, rat ITGA2B. The antigen is synthetic peptide of human cd41.
Gene Expression
Tested Data
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31169/1877_G7_33_selected.jpg
Normal Tissue
Figure 2 Bone marrow
Hematopoietic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31168/73889_B_5_4.jpg
RNA Expression
Figure 3 RNA cell line category: Group enriched (HEL, HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000005961-ITGA2B
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WB
Figure 1. Recombinant Rabbit Anti-ITGA2B Antibody (clone R01-1C2) in WB.
Western Blot analysis of CD41 in C6, Hela lysates using Integrin α IIb antibody.
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Specifications
- Immunogen
- Synthetic peptide of human CD41.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Rat ITGA2B
- Species Reactivity
- Human, Rat
- Clone
- R01-1C2
- Applications
- Western Blot
- Conjugate
- Unconjugated
- MW
- Calculated MW: 113 kDa; Observed MW: 137 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Integrin Subunit Alpha 2b
- Gene ID
- 3674
- UniProt ID
- P08514
- Sequence Similarities
- Belongs to the integrin alpha chain family.
- Cellular Localization
- Membrane
- Protein Refseq
- NP_000410.2
- Function
- Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| PFBL-740 | Human Anti-ITGA2B Recombinant Antibody (clone RUC-2); Fab Fragment | Block | Human Fab |
| HPAB-0275-YC-F(E) | Mouse Anti-ITGA2B Recombinant Antibody; Fab Fragment (HPAB-0275-YC-F(E)) | ELISA, FuncS | Mouse Fab |
| HPAB-0276-YC-F(E) | Mouse Anti-ITGA2B Recombinant Antibody; Fab Fragment (HPAB-0276-YC-F(E)) | FuncS | Mouse Fab |
| HPAB-0277-YC-F(E) | Human Anti-ITGA2B Recombinant Antibody; Fab Fragment (HPAB-0277-YC-F(E)) | FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-740 | Human Anti-ITGA2B Recombinant Antibody (clone RUC-2); scFv Fragment | Block | Human scFv |
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| HPAB-0276-YC-S(P) | Mouse Anti-ITGA2B Recombinant Antibody; scFv Fragment (HPAB-0276-YC-S(P)) | FuncS | Mouse scFv |
| HPAB-0277-YC-S(P) | Human Anti-ITGA2B Recombinant Antibody; scFv Fragment (HPAB-0277-YC-S(P)) | FuncS | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0056MZ | Recombinant Mouse Anti-Human CD41 Antibody (clone TZ.23) | WB, IP, FC | Mouse antibody |
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| HPAB-0276-YC | Mouse Anti-ITGA2B Recombinant Antibody (HPAB-0276-YC) | FuncS | Mouse IgG1, κ |
| HPAB-0277-YC | Human Anti-ITGA2B Recombinant Antibody (HPAB-0277-YC) | FuncS | Humanized IgG |
| VS1-YJ27 | Mouse Anti-ITGA2B Recombinant Antibody (clone M148) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1546CQ | Recombinant Mouse Anti-ITGA2B Antibody (HIP8) | CyTOF, FuncS, FC, IFC, IHC, Neut | IgG1, κ |
| CAT | Product Name | Application | Type |
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| NEUT-1547CQ | Recombinant Mouse Anti-ITGA2B Antibody (PAC1) | FC, IP, WB, BL | IgM, κ |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| VS-1124-YJ7 | Human Anti-ITGA2B Recombinant Autoantibody (clone 2E7) | ELISA, FuncS | Human IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY85 | Human Anti-ITGA2B scFv-Fc Chimera (VS-0425-FY85) | FC, Block | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC591 | Recombinant Anti-ITGA2B Vesicular Antibody, EV Displayed (VS-0425-YC591) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3618 | Anti-ITGA2B Immunohistochemistry Kit | IHC | |
| VS-0525-XY3619 | Anti-Mouse ITGA2B Immunohistochemistry Kit | IHC |
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