Recombinant Anti-ITGA4 Vesicular Antibody, EV Displayed (VS-0425-YC410)
CAT#: VS-0425-YC410
The Recombinant Anti-ITGA4 Vesicular Antibody, EV Displayed (VS-0425-YC410) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ITGA4-expressed cells or tissues. The ITGA4 is an integrin alpha chain, forming dimers with other subunits, playing roles in cell motility and serving as a therapeutic target.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74961/1608_C10_1_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (fHDF/TERT166, HEL, JURKAT, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115232-ITGA4
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ITGA4
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Integrin subunit alpha 4
- Biological Process
- Cell adhesion
- Molecular Function
- Integrin, Receptor
- Cellular Localization
- Plasma membrane
- Introduction
- The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
- Alternative Names
- CD49D
- Gene ID
- 3676
- UniProt ID
- P13612
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC410. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ITGA4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-135 | Anti-Human Integrin alpha 4 beta 7 Recombinant Antibody (Etrolizumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L029G | anti-ITGA4 immunotoxin 15A8 (IgG)-Gel | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-249 | Human Anti-ITGA4 Recombinant Antibody (clone MAb 21.6) | Neut, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-360 | Human Anti-ITGA4 Recombinant Antibody (clone HP1/2) | FC, ELISA, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-249 | Human Anti-ITGA4 Recombinant Antibody (clone MAb 21.6); scFv Fragment | Neut, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-360 | Human Anti-ITGA4 Recombinant Antibody (clone HP1/2); scFv Fragment | FC, ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-249 | Human Anti-ITGA4 Recombinant Antibody (clone MAb 21.6); Fab Fragment | Neut, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-360 | Human Anti-ITGA4 Recombinant Antibody (clone HP1/2); Fab Fragment | FC, ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-717LC | Anti-human ITGA4 Recombinant Antibody (IN 10) (TAB-717LC) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-717LC-S(P) | Anti-human ITGA4 scFv Fragment (IN 10) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-717LC-F(E) | Anti-human ITGA4 Fab Fragment (IN 10) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1193MZ | Recombinant Mouse Anti-Human ITGA4 Antibody (clone 55I7) | FC, IHC-Fr, IP, WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-122 | Recombinant Mouse Anti-Integrin alpha 4 Antibody (ACT-1) | Neut, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-122-S (P) | Recombinant Mouse Anti-Integrin alpha 4 Antibody scFv Fragment (ACT-1) | Neut, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-122-F (E) | Recombinant Mouse Anti-Integrin alpha 4 Antibody Fab Fragment (ACT-1) | Neut, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1549CQ | Recombinant Mouse Anti-ITGA4 Antibody (NEUT-1549CQ) | BL | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1550CQ | Recombinant Rat Anti-Itga4 Antibody (9C10(MFR4.B)) | FC, BL, IHC | IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1551CQ | Recombinant Rat Anti-Itga4 Antibody (R1-2) | FC, IP, BL, IHC | IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1552CQ | Recombinant Rat Anti-Itga4 Antibody (PS/2) | FC, BL | IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1553CQ | Recombinant Rat Anti-Itga4 Antibody (CBL914) | FC, Neut | IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1873 | Hi-Affi™ Recombinant Rabbit Anti-ITGA4 Monoclonal Antibody (DS1873AB) | ICC, IF, IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0848-CN | Recombinant Rabbit Anti-ITGA4 Monoclonal Antibody (JA09-36) | WB, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-135 | Afuco™ Anti-ITGA4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-135) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FN-044CQ | Recombinant Mouse Anti-ITGA4 Antibody (BU49) | FC, Block | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0466-YJ-S(P) | Human Anti-ITGA4 Recombinant Antibody (clone IN9A); scFv Fragment | ELISA, FC, Block | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0466-YJ-F(E) | Human Anti-ITGA4 Recombinant Antibody (clone IN9A); Fab Fragment | ELISA, FC, Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1588WJ-F(E) | Mouse Anti-ITGA4 Recombinant Antibody; Fab Fragment (clone TA2) | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1620WJ-F(E) | Mouse Anti-ITGA4 Recombinant Antibody; Fab Fragment (clone HP1 / 2) | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1588WJ-S(P) | Mouse Anti-ITGA4 Recombinant Antibody; scFv Fragment (clone TA2) | ELISA, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1620WJ-S(P) | Mouse Anti-ITGA4 Recombinant Antibody; scFv Fragment (clone HP1 / 2) | ELISA, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY55 | Human Anti-ITGA4 scFv-Fc Chimera (VS-0425-FY55) | ELISA | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3623 | Anti-ITGA4 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3624 | Anti-Mouse ITGA4 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA
-5.jpg)
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: FC
Application: ELISA, FuncS
Application: ELISA, Vaccine, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
