Human Anti-ITGA4 Recombinant Antibody (clone HP1/2); Fab Fragment
CAT#: PFBL-360
Recombinant Human Antibody (HP1/2) is capable of binding to α4 integrin, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-α4 integrin fab and CH1-3 region of human fab and a light chain (LC) encoding VL from anti-α4 integrin fab and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74961/1608_C10_1_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (fHDF/TERT166, HEL, JURKAT, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115232-ITGA4
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Specifications
- Immunogen
- Human integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
- Host Species
- Human
- Derivation
- Human
- Type
- Human Fab
- Specificity
- Human ITGA4
- Species Reactivity
- Human
- Clone
- HP1/2
- Applications
- FC, ELISA, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ITGA4; integrin; alpha 4 (antigen CD49D; alpha 4 subunit of VLA-4 receptor); IA4; CD49D; integrin alpha-4; 269C wild type; integrin alpha 4; integrin alpha-IV; VLA-4 subunit alpha; integrin alpha-4 subunit; CD49 antigen-like family member D; antigen CD49D; alpha-4 subunit of VLA-4 receptor; very late activation protein 4 receptor; alpha 4 subunit
- Gene ID
- 3676
- UniProt ID
- P13612
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone HP1/2"
- CAT
- Product Name
See other products for "ITGA4"
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| PSBL-249 | Human Anti-ITGA4 Recombinant Antibody (clone MAb 21.6); scFv Fragment | Neut, FuncS | Human scFv |
| PSBL-360 | Human Anti-ITGA4 Recombinant Antibody (clone HP1/2); scFv Fragment | FC, ELISA, FuncS | Human scFv |
| HPAB-1588WJ-S(P) | Mouse Anti-ITGA4 Recombinant Antibody; scFv Fragment (clone TA2) | ELISA, WB | Mouse scFv |
| HPAB-1620WJ-S(P) | Mouse Anti-ITGA4 Recombinant Antibody; scFv Fragment (clone HP1 / 2) | ELISA, WB | Mouse scFv |
| HPAB-1621WJ-S(P) | Human Anti-ITGA4 Recombinant Antibody; scFv Fragment (clone huHP1 / 2) | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-249 | Human Anti-ITGA4 Recombinant Antibody (clone MAb 21.6); Fab Fragment | Neut, FuncS | Human Fab |
| HPAB-0466-YJ-F(E) | Human Anti-ITGA4 Recombinant Antibody (clone IN9A); Fab Fragment | ELISA, FC, Block | Human Fab |
| HPAB-1588WJ-F(E) | Mouse Anti-ITGA4 Recombinant Antibody; Fab Fragment (clone TA2) | ELISA, WB | Mouse Fab |
| HPAB-1620WJ-F(E) | Mouse Anti-ITGA4 Recombinant Antibody; Fab Fragment (clone HP1 / 2) | ELISA, WB | Mouse Fab |
| HPAB-1621WJ-F(E) | Human Anti-ITGA4 Recombinant Antibody; Fab Fragment (clone huHP1 / 2) | ELISA, WB | Human Fab |
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-135 | Afuco™ Anti-ITGA4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-135) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
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| VS-0425-FY55 | Human Anti-ITGA4 scFv-Fc Chimera (VS-0425-FY55) | ELISA | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC410 | Recombinant Anti-ITGA4 Vesicular Antibody, EV Displayed (VS-0425-YC410) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
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| VS-0525-XY3623 | Anti-ITGA4 Immunohistochemistry Kit | IHC | |
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