Human Anti-ITGA4 Recombinant Antibody (clone HP1/2); Fab Fragment (CAT#: PFBL-360)
Recombinant Human Antibody (HP1/2) is capable of binding to α4 integrin, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-α4 integrin fab and CH1-3 region of human fab and a light chain (LC) encoding VL from anti-α4 integrin fab and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74961/1608_C10_1_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74961/1608_C10_1_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (fHDF/TERT166, HEL, JURKAT, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115232-ITGA4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115232-ITGA4
Specifications
- Immunogen
- Human integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
- Host Species
- Human
- Derivation
- Human
- Type
- Human Fab
- Specificity
- Human ITGA4
- Species Reactivity
- Human
- Clone
- HP1/2
- Applications
- FC, ELISA, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ITGA4; integrin; alpha 4 (antigen CD49D; alpha 4 subunit of VLA-4 receptor); IA4; CD49D; integrin alpha-4; 269C wild type; integrin alpha 4; integrin alpha-IV; VLA-4 subunit alpha; integrin alpha-4 subunit; CD49 antigen-like family member D; antigen CD49D; alpha-4 subunit of VLA-4 receptor; very late activation protein 4 receptor; alpha 4 subunit
- Gene ID
- 3676
- UniProt ID
- P13612
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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