Recombinant Rabbit Anti-MMP14 Antibody (clone R05-6H5) (CAT#: VS3-FY938)
This product is a recombinant rabbit antibody that recognizes MMP14. This antibody has been reported for use in Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation. The clone R05-6H5 is specific for human, Hamster MMP14. The antigen is synthetic peptide of human mmp14.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
WB
Figure 1. Recombinant Rabbit Anti-MMP14 Antibody (clone R05-6H5) in WB.
Western Blot analysis of MMP14 in CHO-K1 lysates using MMP14 antibody.
IHC-P
Figure 2. Recombinant Rabbit Anti-MMP14 Antibody (clone R05-6H5) in IHC-P.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using an antibody to MMP14. High pressure and high temperature sodium citrate pH 6.0 for antigen retrieval.
Specifications
- Immunogen
- Synthetic peptide of human MMP14.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Hamster MMP14
- Species Reactivity
- Human, Hamster
- Clone
- R05-6H5
- Applications
- Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation
- Conjugate
- Unconjugated
- MW
- Calculated MW: 66 kDa; Observed MW: 66 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry-Paraffin: 1/50-1/100
Immunoprecipitation: 1/20
Target
- Alternative Names
- Matrix Metallopeptidase 14; Matrix Metallopeptidase 14 (Membrane-Inserted); Membrane-Type-1 Matrix Metalloproteinase; Membrane Type 1 Metalloprotease; EC 3.4.24.80; MT-MMP 1; MT1-MMP; MMP-14; MMP-X1
- Gene ID
- 4323
- UniProt ID
- P50281
- Sequence Similarities
- Belongs to the peptidase M10A family.
- Cellular Localization
- Cytoplasm, Membrane
- Post Translation Modifications
- The precursor is cleaved by a furin endopeptidase.
Tyrosine phosphorylated by PKDCC/VLK.
- Protein Refseq
- NP_004986.1
- Function
- Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (By similarity).
May be involved in actin cytoskeleton reorganization by cleaving PTK7 (PubMed:20837484).
Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2 (PubMed:12714657).
Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (PubMed:22330140).
Recommended Products
Secondary Antibody
Isotype Control
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MMP14"
Select a product category from the dropdown menu below to view related products.
Please select product type
Single Domain Antibody Products
Fab Antibody Products
ScFv Antibody Products
Human Antibody Products
Chicken IgY Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
IgM Antibody Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-865-VHH | Recombinant Anti-human MMP14 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS3-FY938. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
-2.png)
Application: IB, ELISA, FC, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, PD, Activ, PK, Stim
Application: Neut, ELISA, WB, SPR, IF, EM
Application: ELISA, WB, Microarray, Block
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
