Recombinant Rabbit Anti-STAT6 Antibody (clone R07-1H8) (CAT#: VS3-FY1402)
This product is a recombinant rabbit antibody that recognizes STAT6. This antibody has been reported for use in Western Blot. The clone R07-1H8 is specific for human, mouse, rat, Hamster STAT6. The antigen is synthetic peptide of human stat6.
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WB
Figure 1. Recombinant Rabbit Anti-STAT6 Antibody (clone R07-1H8) in WB.
Western Blot analysis of STAT6 in Jurkat, CHO-K1, Hela lysates using STAT6 Antibody.
Specifications
- Immunogen
- Synthetic peptide of human STAT6.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat, Hamster STAT6
- Species Reactivity
- Human, Mouse, Rat, Hamster
- Clone
- R07-1H8
- Applications
- Western Blot
- Conjugate
- Unconjugated
- MW
- Calculated MW: 94 kDa; Observed MW: 110 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- STAT6; Signal transducer and activator of transcription 6; IL-4 Stat
- Gene ID
- 6778
- UniProt ID
- P42226
- Sequence Similarities
- Belongs to the transcription factor STAT family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4 (PubMed:27796300).
Tyrosine phosphorylated following stimulation by IL3/interleukin-3 (By similarity).
Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling (PubMed:17210636).
Mono-ADP-ribosylated by PARP14.
- Protein Refseq
- NP_001171549.1; NP_001171550.1; NP_001171551.1
- Function
- Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0567MZ | Chicken Anti-STAT6 Polyclonal IgY | WB | Chicken antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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