Recombinant Mouse Anti-TPO Antibody (clone 9G3-6F3-9B7) (CAT#: VS3-FY1477)

This product is a recombinant mouse antibody that recognizes TPO. This antibody has been reported for use in Immunohistochemistry-Paraffin. The clone 9G3-6F3-9B7 is specific for human TPO. The antigen is synthetic peptide derived from human thyroid peroxidase (tpo).


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IHC-P

Figure 1. Recombinant Mouse Anti-TPO Antibody (clone 9G3-6F3-9B7) in IHC-P.

Figure 1. Recombinant Mouse Anti-TPO Antibody (clone 9G3-6F3-9B7) in IHC-P.

Immunohistochemical analysis of paraffin-embedded follicular thyroid carcinoma using thyroid peroxidase antibody. Antigen retrieval was performed using high pressure and high temperature sodium citrate pH 6.0.


Specifications

  • Immunogen
  • Synthetic peptide derived from human thyroid peroxidase (TPO).
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2b
  • Specificity
  • Human TPO
  • Species Reactivity
  • Human
  • Clone
  • 9G3-6F3-9B7
  • Applications
  • Immunohistochemistry-Paraffin
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Affinity Chromatography
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • PBS, pH 7.3, 50% glycerol, 0.5% BSA
  • Preservative
  • 0.02% Sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Immunohistochemistry-Paraffin: 1/100-1/500

Target

  • Alternative Names
  • Thyroid Peroxidase; EC 1.11.1.8; Thyroid Microsomal Antigen; Thyroperoxidase; EC 1.11.1; TDH2A; MSA; TPX
  • Sequence Similarities
  • Belongs to the peroxidase family. XPO subfamily.
  • Cellular Localization
  • Membrane
  • Post Translation Modifications
  • Glycosylated.
    Heme is covalently bound through a H2O2-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface.
    Cleaved in its N-terminal part.
  • Function
  • Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T3 and T4.

Recommended Products

Reconstitution Buffer

Recommended Dilution Buffer

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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