Recombinant Rabbit Anti-VEGFA Antibody (clone R04-6D7) (CAT#: VS3-FY1543)

This product is a recombinant rabbit antibody that recognizes VEGFA. This antibody has been reported for use in Western Blot. The clone R04-6D7 is specific for human, mouse, rat VEGFA. The antigen is human vegfa synthetic peptide.


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WB

Figure 1. Recombinant Rabbit Anti-VEGFA Antibody (clone R04-6D7) in WB.

Figure 1. Recombinant Rabbit Anti-VEGFA Antibody (clone R04-6D7) in WB.

Western Blot analysis of VEGFA in RAW264.7 lysates using VEGFA antibody.


Specifications

  • Immunogen
  • Human VEGFA Synthetic Peptide.
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse, Rat VEGFA
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R04-6D7
  • Applications
  • Western Blot
  • Conjugate
  • Unconjugated
  • MW
  • Calculated MW: 27 kDa; Observed MW: 25-50 kDa

Product Property

  • Purification
  • Affinity Purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% glycerol, 0.05% BSA
  • Preservative
  • 0.01% Sodium azide
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000

Target

  • Alternative Names
  • Vascular Endothelial Growth Factor A; Vascular Permeability Factor; VEGF; VPF; Vascular Endothelial Growth Factor A121; Vascular Endothelial Growth Factor A165; Vascular Endothelial Growth Factor; VEGF-A; MVCD1
  • Sequence Similarities
  • Belongs to the PDGF/VEGF growth factor family.
  • Cellular Localization
  • Secreted
  • Function
  • Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).
    Also binds the DEAR/FBXW7-AS1 receptor (PubMed:17446437).

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "VEGFA"

Humanized Antibody

CAT Product Name Application Type
TAB-H73 Anti-Human VEGFA Recombinant Antibody (Vanucizumab) WB, FC, IP, ELISA, Neut, FuncS, IF VH - C-kappa - CH2 - CH3 _ V-lambda - CH1 _ H-GAMMA-1 _ L-kappa
TAB-011 Anti-Human VEGF Recombinant Antibody (Bevacizumab) FC, IP, ELISA, Neut, FuncS, IF, ICC IgG1 - kappa
TAB-012-F(E) Anti-Human VEGF Recombinant Antibody Fab Fragment (Ranibizumab) IP, IF, FuncS, FC, Neut, ELISA, IHC Fab - G1 - kappa
TAB-307CQ Human Anti-VEGFA Recombinant Antibody (TAB-307CQ) Inhib Human IgG
TAB-307CQ-S(P) Human Anti-VEGFA Recombinant Antibody; scFv Fragment (TAB-307CQ-S(P)) ELISA, Neut Human scFv

Immunotoxin

CAT Product Name Application Type
AGTO-L043L anti-VEGFA immunotoxin Ng76 (scFv)-Luffin-β Cytotoxicity assay, Functional assay

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0623MZ Chicken Anti-VEGF Polyclonal IgY WB Chicken antibody

Neutralizing Antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-2259CQ Mouse Anti-VEGFA Recombinant Antibody (clone A.4.6.1) ELISA, IP, WB, Block, FC, IHC Mouse IgG1, κ
NEUT-2267CQ Mouse Anti-VEGFA Recombinant Antibody (clone A15136B) WB, Block Mouse IgG2b, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3835 Rabbit Anti-VEGFA Recombinant Antibody (clone DS3835AB) FC, ICC, IF, IHC-P, IP, WB Rabbit IgG
MOR-4758 Rabbit Anti-Vegfa Recombinant Antibody (clone TH272DS) WB Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-465CQ Afuco™ Anti-VEGFA ADCC Recombinant Antibody (Varisacumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody
AFC-TAB-011 Afuco™ Anti-VEGFA ADCC Recombinant Antibody (Bevacizumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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