Recombinant Anti-VTCN1 Vesicular Antibody, EV Displayed (VS-0425-YC263) (CAT#: VS-0425-YC263)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• VTCN1

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• V-set domain containing T cell activation inhibitor 1

• Biological Process
• Adaptive immunity, Immunity

• Cellular Localization
• Plasma membrane, Cell Junctions, Focal adhesion sites

• Introduction
• This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

• Alternative Names
• B7-H4, B7H4, B7S1, B7x, FLJ22418

• Gene ID
• 79679

• UniProt ID
• Q7Z7D3

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