Recombinant Anti-VTCN1 Vesicular Antibody, EV Displayed (VS-0425-YC263)
CAT#: VS-0425-YC263
The Recombinant Anti-VTCN1 Vesicular Antibody, EV Displayed (VS-0425-YC263) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to VTCN1-expressed cells or tissues. The VTCN1 is a B7 family protein involved in tumor progression, expressed on antigen-presenting cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/1356_C9_3_selected.jpg
Normal Tissue
Figure 2 IHC staining of human breast
Immunohistochemical staining of human breast shows moderate membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/ihc_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_4_6.jpg
Normal Tissue
Figure 6 Breast
Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_B_3_4.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enriched (SK-BR-3)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134258-VTCN1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- VTCN1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- V-set domain containing T cell activation inhibitor 1
- Biological Process
- Adaptive immunity, Immunity
- Cellular Localization
- Plasma membrane, Cell Junctions, Focal adhesion sites
- Introduction
- This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
- Alternative Names
- B7-H4, B7H4, B7S1, B7x, FLJ22418
- Gene ID
- 79679
- UniProt ID
- Q7Z7D3
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Datasheet
MSDS
COA
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1102CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1102CL) | ELISA | Humanized IgG1, κ |
| TAB-1103CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1103CL) | ELISA | Humanized IgG1, κ |
| TAB-1104CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1104CL) | ELISA | Humanized IgG1, κ |
| TAB-1105CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1105CL) | ELISA | Humanized IgG1, κ |
| TAB-1106CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1106CL) | ELISA | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1110CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1110CL) | ELISA, FC | Chimeric (Mouse/Human) IgG4 |
| TAB-1112CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1112CL) | ELISA, FC | Chimeric (Mouse/Human) IgG4 |
| TAB-1114CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1114CL) | ELISA, FC | Chimeric (Mouse/Human) IgG4 |
| TAB-1110CL-S(P) | Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1110CL-S(P)) | ELISA, FC | Human scFv |
| TAB-1112CL-S(P) | Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1112CL-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1116CL | Mouse Anti-VTCN1 Recombinant Antibody (TAB-1116CL) | ELISA | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1117CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1117CL) | ELISA, FC, FuncS | Human IgG |
| TAB-1118CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1118CL) | ELISA, FC, FuncS | Human IgG |
| TAB-1119CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1119CL) | ELISA, FC, FuncS | Human IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1101CL-S(P) | Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1101CL-S(P)) | ELISA, WB, FC, FuncS | Mouse scFv |
| TAB-1109CL-S(P) | Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1109CL-S(P)) | ELISA, FC | Mouse scFv |
| TAB-1111CL-S(P) | Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1111CL-S(P)) | ELISA, FC | Mouse scFv |
| TAB-1113CL-S(P) | Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1113CL-S(P)) | ELISA, FC | Mouse scFv |
| TAB-1115CL-S(P) | Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1115CL-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2275CQ | Rat Anti-Vtcn1 Recombinant Antibody (clone 188) | FC, FuncS, Neut | Rat IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3857 | Rabbit Anti-VTCN1 Recombinant Antibody (clone DS3857AB) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0405-YC-S(P) | Mouse Anti-VTCN1 Recombinant Antibody (clone 278M1); scFv Fragment | FC | Mouse scFv |
| HPAB-N0406-YC-S(P) | Human Anti-VTCN1 Recombinant Antibody (clone 278M1 L2H2); scFv Fragment | FC, Inhib | Human scFv |
| HPAB-0335CQ-S(P) | Human Anti-VTCN1 Recombinant Antibody scFv Fragment (HPAB-0335CQ-S(P)) | ELISA, FC | Human scFv |
| HPAB-0336CQ-S(P) | Human Anti-VTCN1 Recombinant Antibody scFv Fragment (HPAB-0336CQ-S(P)) | ELISA, FC | Human scFv |
| HPAB-0337CQ-S(P) | Human Anti-VTCN1 Recombinant Antibody scFv Fragment (HPAB-0337CQ-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0405-YC-F(E) | Mouse Anti-VTCN1 Recombinant Antibody (clone 278M1); Fab Fragment | FC | Mouse Fab |
| HPAB-N0406-YC-F(E) | Human Anti-VTCN1 Recombinant Antibody (clone 278M1 L2H2); Fab Fragment | FC, Inhib | Human Fab |
| HPAB-N0297-YC-F(E) | Mouse Anti-VTCN1 Recombinant Antibody (clone B7H4/1E10); Fab Fragment | ELISA, WB | Mouse Fab |
| HPAB-1811-FY-S(P) | Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (HPAB-1811-FY-S(P)) | ELISA | Human scFv |
| HPAB-1812-FY-S(P) | Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (HPAB-1812-FY-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY232 | CytoStream™ Mouse Anti-VTCN1 Recombinant Antibody (clone MIH43) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2478 | Anti-VTCN1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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