Mouse Anti-VTCN1 Recombinant Antibody (clone 5F6) (CAT#: HPAB-0305-CN)
An isolated antibody targeting human B7-H4 expressed on many human cancers including but not limited to breast, ovarian, and renal cancers can be applied to produce CAR cells, which are safe and effective in patients and can be used to treat human tumors expressing the B7-H4 surface protein.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/1356_C9_3_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/1356_C9_3_selected.jpg
Figure 2 IHC staining of human breast
(Immunohistochemical staining of human breast shows moderate membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/ihc_selected.jpg
(Immunohistochemical staining of human breast shows moderate membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/ihc_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_9_3.jpg
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_9_3.jpg
Figure 4 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_8_5.jpg
Figure 5 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_4_6.jpg
Figure 6 Breast
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_B_3_4.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_B_3_4.jpg
Figure 7 Lymph node
(Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_7_8.jpg
(Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_7_8.jpg
Figure 8 RNA cell line category: Cell line enriched (SK-BR-3)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134258-VTCN1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134258-VTCN1
Specifications
- Immunogen
- Human B7-H4 signal and extracellular domains fused to the Fc region of human IgG1 (KLH-conjugated huB7-H4-Fc)
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human VTCN1
- Species Reactivity
- Human
- Clone
- 5F6
- Applications
- ELISA, FC, IHC
- Related Disease
- Tumor
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1110CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1110CL) | ELISA, FC | Chimeric (Mouse/Human) IgG4 |
| TAB-1112CL | Human Anti-VTCN1 Recombinant Antibody (TAB-1112CL) | ELISA, FC | Chimeric (Mouse/Human) IgG4 |
| TAB-1110CL-S(P) | Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1110CL-S(P)) | ELISA, FC | Human scFv |
| TAB-1112CL-S(P) | Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1112CL-S(P)) | ELISA, FC | Human scFv |
| TAB-1114CL-S(P) | Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1114CL-S(P)) | ELISA, FC | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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