VTCN1

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Anti-VTCN1 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs offers extensive support for users of the VTCN1 recombinant antibody, ensuring that researchers have all the resources they need to achieve successful outcomes. Our dedicated team of skilled scientists is on hand to provide guidance on experimental design, refining assay conditions, and addressing any troubleshooting issues that may arise. We prioritize the success of your research by being available to respond to any questions related to product application, storage, and handling. Furthermore, we provide essential validation data and tailored protocols, empowering researchers to attain dependable and reproducible results when utilizing the antibody in their studies.

VTCN1: A Versatile and Crucial Target for Tumor

VTCN1 (also known as B7H4) has emerged as a potential therapeutic target due to its negative costimulatory properties and its abnormal expression in various tumors. The elevated levels of VTCN1 observed in numerous cancers correlate with the modulation of several pathways that allow tumors to escape detection by the immune system. With minimal expression in normal tissues and significant overexpression in cancerous cells, VTCN1 presents itself as a compelling candidate for immunotherapy, potentially offering a safer alternative to treatments targeting anti-PD-1 and PD-L1.

Alternative Names

V-set domain-containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; B7 homolog 4; B7H4; B7-H4; B7h.5; B7X; B7S1.

Background

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein have been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Anti-VTCN1 rAb Products

Our anti-VTCN1 recombinant antibody products provide a comprehensive range of formulations and conjugation options to suit different experimental needs, including monoclonal antibodies, polyclonal antibodies, ADCs, and recombinant antibody fragments. These recombinant antibodies are engineered to enhance efficacy and precision, rendering them essential research instruments for investigating the function of VTCN1 in cancer progression and possibly for creating targeted cancer treatments. Below, we present a selection of antibodies that effectively inhibit VTCN1.

Table 1. Featured anti-VTCN1 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs offers VTCN1 recombinant antibody products that undergo a rigorous quality assurance process, guaranteeing the utmost product excellence. Our comprehensive quality control program enables us to deliver dependable and high-performance VTCN1 recombinant antibodies, meeting the demands of researchers and clinicians engaged in immunotherapy and cancer research.

Customer Reviews

Excellent

Ra***v
Human Anti-VTCN1 Recombinant Antibody (clone sc209) (HPAB-0335CQ) (CAT#: HPAB-0335CQ)

I recently purchased the Human Anti-VTCN1 Recombinant Antibody (clone sc209) for my research on cancer immunotherapy, and I couldn't be more satisfied with the results. The antibody demonstrated exceptional specificity and sensitivity in my ELISA assay, allowing for accurate quantification of VTCN1 levels in my samples. The comprehensive data sheet provided was invaluable, detailing optimal conditions for use. The product worked wonderfully, and the customer support crew was really attentive and helpful. A satisfying purchase.

17/Oct/2022

Excellent

Ta***c
Anti-Human VTCN1 Recombinant Antibody (TAB-664CL) (CAT#: TAB-664CL)

I recently employed the Anti-Human VTCN1 Recombinant Antibody from Creative Biolabs for my IHC studies, and I was very pleased with its performance. The antibody exhibited remarkable specificity, allowing for precise detection of VTCN1 in my tissue sections. The staining results were both reproducible and clear, significantly enhancing my research into cancer biomarkers.

20/Mar/2023

Excellent

Tr***y
Human Anti-VTCN1 Recombinant Antibody (HPAB-1811-FY) (CAT#: HPAB-1811-FY)

I purchased the Human Anti-VTCN1 Recombinant Antibody from Creative Biolabs to perform an antibody-dependent cellular cytotoxicity (ADCC) assay, and I couldn't be more pleased with the outcome. The antibody showed remarkable efficacy in engaging effector cells, leading to significant target cell lysis in my experiments. Its reliability and performance have made a substantial impact on my research into immune responses against tumor cells. Highly recommended!

11/Jun/2023

rAb Production

Our innovative anti-VTCN1 recombinant antibody production platform leverages genetically modified cells to efficiently produce and release antibodies that specifically bind to the VTCN1 protein. This approach enables large-scale, cost-efficient manufacturing of high-quality antibodies.

Featured Anti-VTCN1 Recombinant Antibody Production Platforms
Fig.4 Milligram-scale anti-VTCN1 recombinant antibody production.

Fig.5 Gram-scale anti-VTCN1 recombinant antibody production.

rAb Modalities

Creative Biolabs is dedicated to delivering a diverse range of high-quality anti-VTCN1 recombinant antibodies in various formats, ensuring that researchers have access to the latest and most advanced tools for their investigations.

Fig.6 Full-length anti-VTCN1 recombinant antibody production and modalities.

VTCN1-Targeted Drug Information

Table 2. Public drug targeting VTCN1.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Creative Biolabs offers an extensive selection of tailor-made anti-VTCN1 recombinant antibodies designed to meet diverse research requirements. Whether your project needs large-scale production or smaller batches, our dedicated team is here to ensure you receive premium-quality products along with swift delivery and exceptional customer support. Reach out to us today to discover more about our anti-VTCN1 antibodies and how we can assist you in achieving your research objectives.