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ADAM17
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- Anti-Human ADAM17 Recombinant Antibody (TAB-015CL)
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- Derivation: Human
- Species Reactivity: Human
- Type: Antibody
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- Anti-Human ADAM17 Recombinant Antibody (B07) (TAB-0667CLV)
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- Species Reactivity: Cross-react with mouse ADAM17
- Type: Fully Human antibody
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- Anti-Human ADAM17 Recombinant Antibody (D1(A12)) (TAB-0669CLV)
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- Type: Human antibody
- Application: ELISA, PK, Inhib, IHC
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- Anti-Human ADAM17 Recombinant Antibody Fab Fragment (B07) (TAB-0667CLV-F(E))
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- Species Reactivity: Cross-react with mouse ADAM17
- Type: Fully Human antibody
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- Anti-Human ADAM17 Recombinant Antibody Fab Fragment (D1(A12)) (TAB-0669CLV-F(E))
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- Type: Human antibody
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- Anti-Human ADAM17 Recombinant Antibody scFv Fragment (B07) (TAB-0667CLV-S(P))
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- Species Reactivity: Cross-react with mouse ADAM17
- Type: Fully Human antibody
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- Anti-Human ADAM17 Recombinant Antibody (cl022C3) (TAB-0445CL)
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- Type: Chimeric (mouse/human)
- Application: ELISA, Inhib, FuncS
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- Anti-Human ADAM17 Recombinant Antibody (hzl022C3) (TAB-0446CL)
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- Type: Humanized Antibody
- Application: ELISA, Inhib, FuncS
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- Anti-Human ADAM17 Recombinant Antibody (hl022C3) (TAB-0447CL)
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- Derivation: Human
- Type: Human antibody
- Application: ELISA, Inhib, FuncS
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- Rabbit Anti-ADAM17 Recombinant Antibody (clone JM10-35) (MRO-0030-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IP, FC
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- PE-A*02:01/Human ADAM17 (YLIELIDRV) MHC Tetramer (MHC-CN0393)
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- Class: Class I
- Antigen: ADAM17
- Antigen Species: Human
- Peptide: YLIELIDRV
- Conjugate: PE
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- APC-A*02:01/Human ADAM17 (YLIELIDRV) MHC Tetramer (MHC-CN0394)
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- Class: Class I
- Antigen: ADAM17
- Antigen Species: Human
- Peptide: YLIELIDRV
- Conjugate: APC
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- Human Anti-ADAM17 Antibody, mRNA (TAB-015CL-mRNA)
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- Species Reactivity: Human
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- Anti-Human ADAM17 Recombinant Antibody scFv Fragment (D1(A12)) (TAB-0669CLV-S(P))
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- Type: Human antibody
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- Mouse Anti-ADAM17 Recombinant Antibody (clone 1F6) (MOB-0437MZ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, IF, IHC-P, WB
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- AbPlus™ Anti-ADAM17 Magnetic Beads (VS-0724-YC601) (VS-0724-YC601)
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- Target: ADAM17
- Target Species: Human
- Application: IP, Protein Purification
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- FITC-A*02:01/Human ADAM17 (YLIELIDRV) MHC Tetramer (MHC-CN0395)
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- Class: Class I
- Antigen: ADAM17
- Antigen Species: Human
- Peptide: YLIELIDRV
- Conjugate: FITC
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- A*02:01/Human ADAM17 (YLIELIDRV) MHC Tetramer (MHC-CN0396)
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- Class: Class I
- Antigen: ADAM17
- Antigen Species: Human
- Peptide: YLIELIDRV
- Conjugate: Unconjugated
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- Anti-Human ADAM17 Recombinant Antibody scFv Fragment (cl022C3) (TAB-0445CL-S(P))
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- Type: Chimeric (mouse/human)
- Application: ELISA, Inhib, FuncS
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- Anti-Human ADAM17 Recombinant Antibody scFv Fragment (hzl022C3) (TAB-0446CL-S(P))
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- Type: Humanized Antibody
- Application: ELISA, Inhib, FuncS
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- Anti-Human ADAM17 Recombinant Antibody scFv Fragment (hl022C3) (TAB-0447CL-S(P))
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- Derivation: Human
- Type: Human antibody
- Application: ELISA, Inhib, FuncS
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- Anti-Human ADAM17 Recombinant Antibody Fab Fragment (cl022C3) (TAB-0445CL-F(E))
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- Type: Chimeric (mouse/human)
- Application: ELISA, Inhib, FuncS
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- Anti-Human ADAM17 Recombinant Antibody Fab Fragment (hzl022C3) (TAB-0446CL-F(E))
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- Type: Humanized Antibody
- Application: ELISA, Inhib, FuncS
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- Anti-Human ADAM17 Recombinant Antibody Fab Fragment (hl022C3) (TAB-0447CL-F(E))
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- Derivation: Human
- Type: Human antibody
- Application: ELISA, Inhib, FuncS
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- Anti-Human ADAM17 Recombinant Antibody Fab Fragment (ml022C3) (TAB-0444CL-F(E))
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- Application: ELISA, Inhib, FuncS
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- Anti-Human ADAM17 Recombinant Antibody scFv Fragment (ml022C3) (TAB-0444CL-S(P))
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- Application: ELISA, Inhib, FuncS
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: IP, IF, Biosensors, FuncS
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- Recombinant Anti-human ADAM17 Antibody Fab Fragment (MOB-38-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, WB, FuncS
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- Recombinant Anti-human ADAM17 Antibody scFv Fragment (MOB-38-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, IP, FuncS
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- Anti-Human ADAM17 Recombinant Antibody scFv Fragment (C6-30) (TAB-0668CLV-S(P))
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- Anti-Human ADAM17 Recombinant Antibody Fab Fragment (C6-30) (TAB-0668CLV-F(E))
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- Anti-Human ADAM17 Recombinant Antibody (C6-30) (TAB-0668CLV)
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- Anti-Human ADAM17 Recombinant Antibody (ml022C3) (TAB-0444CL)
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- Application: ELISA, Inhib, FuncS
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- Anti-ADAM17 Immunohistochemistry Kit (VS-0325-XY41)
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- Species Reactivity: Human, Mouse, Rat
- Target: ADAM17
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, IF, IP, FC
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- Anti-Human ADAM17 Immunohistochemistry Kit (VS-0525-XY149)
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- Species Reactivity: Human
- Target: ADAM17
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
Protein class
CD markers, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Suprabasal keratinocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with MAD2L1, MAPK14 and MUC1 (PubMed:12441351, 20188673). Interacts with iRhom1/RHBDF1 and iRhom2/RHBDF2 (PubMed:29897333). Interacts with FRMD8 via its interaction with iRhom1/RHBDF1 and iRhom2/RHBDF2 (PubMed:29897333).
Molecular function
Hydrolase, Metalloprotease, Protease
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