Recombinant Human Anti-human ADAM17 Antibody scFv Fragment

Name: Recombinant Human Anti-human ADAM17 Antibody scFv Fragment
SKU: MHH-38-S(P)
Rating: 5 (1 reviews)

CAT#: MHH-38-S(P)

Recombinant Human Antibody scFv Fragment raises against Human ADAM17, expressed in E. coli.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/if_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51575/if_selected.jpg

Normal Tissue Figure 3 IHC staining of human small intestine

Immunohistochemical staining of human small intestine shows membranous and cytoplasmic positivity.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/ihc_selected.jpg

Normal Tissue Figure 4 Cerebral cortex

Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_B_8_5.jpg

Normal Tissue Figure 5 Colon

Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_7_3.jpg

Normal Tissue Figure 6 Liver

Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_9_4.jpg

Normal Tissue Figure 7 Kidney

Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_7_5.jpg

Normal Tissue Figure 8 Testis

Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_4_6.jpg

Normal Tissue Figure 9 Placenta

Trophoblastic cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_2_7.jpg

Normal Tissue Figure 10 Lymph node

Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10738/26587_A_9_8.jpg

RNA Expression Figure 11 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000151694-ADAM17

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Specifications

Immunogen
Human ADAM metallopeptidase domain 17

Host Species
Human

Derivation
Human

Type
scFv

Specificity
Tested positive against native Human ADAM metallopeptidase domain 17

Species Reactivity
Human

Applications
Antibody assay: Immunoprecipitation; Immunofluorescence; Biosensors; Functional Study

Product Property

Purity
95% by HPLC

Storage
Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.

Target

Alternative Names
ADAM17; ADAM metallopeptidase domain 17; CSVP; TACE; NISBD; ADAM18; CD156B; NISBD1; disintegrin and metalloproteinase domain-containing protein 17; TNF-alpha convertase; snake venom-like protease; TNF-alpha converting enzyme; ADAM metallopeptidase domain

Gene ID
6868

UniProt ID
B2RNB2

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MHH-38-S(P).pdf

MSDS

MSDS - MHH-38-S(P).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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CAT	Product Name	Application	Type
MOB-38-F(E)	Recombinant Anti-human ADAM17 Antibody Fab Fragment	ELISA, WB, FuncS	Fab
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CAT	Product Name	Application	Type
MOB-38-S(P)	Recombinant Anti-human ADAM17 Antibody scFv Fragment	ELISA, WB, IP, FuncS	scFv

CAT	Product Name	Application
TAB-0444CL	Anti-Human ADAM17 Recombinant Antibody (ml022C3)	ELISA, Inhib, FuncS
TAB-0444CL-S(P)	Anti-Human ADAM17 Recombinant Antibody scFv Fragment (ml022C3)	ELISA, Inhib, FuncS
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CAT	Product Name	Application	Type
TAB-0445CL	Anti-Human ADAM17 Recombinant Antibody (cl022C3)	ELISA, Inhib, FuncS	Chimeric (mouse/human)
TAB-0445CL-S(P)	Anti-Human ADAM17 Recombinant Antibody scFv Fragment (cl022C3)	ELISA, Inhib, FuncS	Chimeric (mouse/human)
TAB-0445CL-F(E)	Anti-Human ADAM17 Recombinant Antibody Fab Fragment (cl022C3)	ELISA, Inhib, FuncS	Chimeric (mouse/human)

CAT	Product Name	Application	Type
TAB-0446CL	Anti-Human ADAM17 Recombinant Antibody (hzl022C3)	ELISA, Inhib, FuncS	Humanized Antibody
TAB-0446CL-S(P)	Anti-Human ADAM17 Recombinant Antibody scFv Fragment (hzl022C3)	ELISA, Inhib, FuncS	Humanized Antibody
TAB-0446CL-F(E)	Anti-Human ADAM17 Recombinant Antibody Fab Fragment (hzl022C3)	ELISA, Inhib, FuncS	Humanized Antibody

CAT	Product Name	Application	Type
TAB-0447CL	Anti-Human ADAM17 Recombinant Antibody (hl022C3)	ELISA, Inhib, FuncS	Human antibody
TAB-0447CL-S(P)	Anti-Human ADAM17 Recombinant Antibody scFv Fragment (hl022C3)	ELISA, Inhib, FuncS	Human antibody
TAB-0447CL-F(E)	Anti-Human ADAM17 Recombinant Antibody Fab Fragment (hl022C3)	ELISA, Inhib, FuncS	Human antibody
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CAT	Product Name	Application	Type
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CAT	Product Name	Application
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MHC-CN0395	FITC-A*02:01/Human ADAM17 (YLIELIDRV) MHC Tetramer	FCM, IHC
MHC-CN0396	A*02:01/Human ADAM17 (YLIELIDRV) MHC Tetramer	FCM, IHC
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