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DLL4
This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.
Protein class
Disease related genes, Human disease related genes
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Adipocytes, Endothelial cells, Intestinal goblet cells, Hepatic stellate cells, Distal enterocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (BJ hTERT+, HUVEC TERT2, SCLC-21H)
Interaction
Interacts with NOTCH4. Interacts (via N-terminal DSL and MNNL domains) with NOTCH1 (via EGF-like domains).
Molecular function
Developmental protein
More Types Infomation
- Human Anti-DLL4 Recombinant Antibody (HPAB-0205-CN) (HPAB-0205-CN)
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- Species Reactivity: Human, Monkey
- Type: Human IgG4
- Application: ELISA, WB, FC, IP
Compare
- Human Anti-DLL4 Recombinant Antibody (HPAB-0204-CN) (HPAB-0204-CN)
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- Species Reactivity: Human, Monkey
- Type: Human IgG1
- Application: ELISA, WB, FC, IP
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0205-CN-F(E)) (HPAB-0205-CN-F(E))
-
- Species Reactivity: Human, Monkey
- Type: Human Fab
- Application: ELISA, WB, FC, IP
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0204-CN-F(E)) (HPAB-0204-CN-F(E))
-
- Species Reactivity: Human, Monkey
- Type: Human Fab
- Application: ELISA, WB, FC, IP
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0203-CN-F(E)) (HPAB-0203-CN-F(E))
-
- Species Reactivity: Human, Monkey
- Type: Human Fab
- Application: ELISA, WB, FC, IP
Compare
- Human Anti-DLL4 Recombinant Antibody (clone 4B4) (HPAB-0210-CN)
-
- Species Reactivity: Human, Monkey
- Type: Human IgG1
- Application: ELISA, WB, FC
Compare
- Human Anti-DLL4 Recombinant Antibody (clone 21H3RK) (HPAB-0209-CN)
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- Species Reactivity: Human, Monkey
- Type: Human IgG1
- Application: ELISA, WB, FC
Compare
- Human Anti-DLL4 Recombinant Antibody (HPAB-0208-CN) (HPAB-0208-CN)
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG2
- Application: ELISA, WB, FC, IHC, IF, ICC
Compare
- Mouse Anti-DLL4 Recombinant Antibody (HPAB-0206-CN) (HPAB-0206-CN)
-
- Species Reactivity: Human
- Type: Mouse IgG2
- Application: ELISA, WB, FC, IHC, IF, ICC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0076-CN-F(E)) (HPAB-0076-CN-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0075-CN-F(E)) (HPAB-0075-CN-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB, FC
Compare
- Human Anti-DLL4 Recombinant Antibody (HPAB-0076-CN) (HPAB-0076-CN)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB, FC
Compare
- Human Anti-DLL4 Recombinant Antibody (HPAB-0075-CN) (HPAB-0075-CN)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (HPAB-0205-CN-S(P)) (HPAB-0205-CN-S(P))
-
- Species Reactivity: Human, Monkey
- Type: Human scFv
- Application: ELISA, WB, FC, IP
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (HPAB-0204-CN-S(P)) (HPAB-0204-CN-S(P))
-
- Species Reactivity: Human, Monkey
- Type: Human scFv
- Application: ELISA, WB, FC, IP
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (HPAB-0203-CN-S(P)) (HPAB-0203-CN-S(P))
-
- Species Reactivity: Human, Monkey
- Type: Human scFv
- Application: ELISA, WB, FC, IP
Compare
- Human Anti-DLL4 Recombinant Antibody (HPAB-0207-CN) (HPAB-0207-CN)
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, WB, FC, IHC, IF, ICC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (HPAB-0076-CN-S(P)) (HPAB-0076-CN-S(P))
-
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (HPAB-0075-CN-S(P)) (HPAB-0075-CN-S(P))
-
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB, FC
Compare
- Human Anti-DLL4 Recombinant Antibody (HPAB-0203-CN) (HPAB-0203-CN)
-
- Species Reactivity: Human, Monkey
- Type: Human IgG1
- Application: ELISA, WB, FC, IP
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-239MZ-F(E)) (TAB-239MZ-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: IHC
Compare
- Rat Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-238MZ-F(E)) (TAB-238MZ-F(E))
-
- Species Reactivity: Human
- Type: Rat Fab
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-237MZ-F(E)) (TAB-237MZ-F(E))
-
- Species Reactivity: Human
- Type: Rat Fab
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-236MZ-F(E)) (TAB-236MZ-F(E))
-
- Species Reactivity: Human
- Type: Rat Fab
- Application: ELISA, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-239MZ-S(P)) (TAB-239MZ-S(P))
-
- Species Reactivity: Human
- Type: Human scFv
- Application: IHC
Compare
- Rat Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-238MZ-S(P)) (TAB-238MZ-S(P))
-
- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-237MZ-S(P)) (TAB-237MZ-S(P))
-
- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-236MZ-S(P)) (TAB-236MZ-S(P))
-
- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-235MZ-F(E)) (TAB-235MZ-F(E))
-
- Species Reactivity: Human
- Type: Rat Fab
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-234MZ-F(E)) (TAB-234MZ-F(E))
-
- Species Reactivity: Human
- Type: Rat Fab
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-233MZ-F(E)) (TAB-233MZ-F(E))
-
- Species Reactivity: Human
- Type: Rat Fab
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-232MZ-F(E)) (TAB-232MZ-F(E))
-
- Species Reactivity: Human
- Type: Rat Fab
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody (12.55) (TAB-231MZ)
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody (12.14) (TAB-230MZ)
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody (12.08) (TAB-229MZ)
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody (12.73) (TAB-228MZ)
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody (1C1) (TAB-227MZ)
-
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-235MZ-S(P)) (TAB-235MZ-S(P))
-
- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-234MZ-S(P)) (TAB-234MZ-S(P))
-
- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-233MZ-S(P)) (TAB-233MZ-S(P))
-
- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-232MZ-S(P)) (TAB-232MZ-S(P))
-
- Species Reactivity: Human
- Type: Rat scFv
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody Fab Fragment (12.55) (TAB-231MZ-F(E))
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody Fab Fragment (12.14) (TAB-230MZ-F(E))
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody Fab Fragment (12.08) (TAB-229MZ-F(E))
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody Fab Fragment (12.73) (TAB-228MZ-F(E))
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody Fab Fragment (1C1) (TAB-227MZ-F(E))
-
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody scFv Fragment (12.55) (TAB-231MZ-S(P))
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody scFv Fragment (12.14) (TAB-230MZ-S(P))
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody scFv Fragment (12.08) (TAB-229MZ-S(P))
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody scFv Fragment (12.73) (TAB-228MZ-S(P))
-
- Derivation: Phage display library
- Type: Human antibody
- Application: ELISA, FC
Compare
- Anti-Human DLL4 Recombinant Antibody scFv Fragment (1C1) (TAB-227MZ-S(P))
-
- Application: ELISA, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-226MZ-F(E)) (TAB-226MZ-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-225MZ-F(E)) (TAB-225MZ-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-224MZ-F(E)) (TAB-224MZ-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-223MZ-F(E)) (TAB-223MZ-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-226MZ) (TAB-226MZ)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-225MZ) (TAB-225MZ)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: Block, FC, FuncS, Inhib
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-224MZ) (TAB-224MZ)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: Block, FC, FuncS, Inhib
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-223MZ) (TAB-223MZ)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-226MZ-S(P)) (TAB-226MZ-S(P))
-
- Species Reactivity: Human
- Type: Human scFv
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-225MZ-S(P)) (TAB-225MZ-S(P))
-
- Species Reactivity: Human
- Type: Human scFv
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-224MZ-S(P)) (TAB-224MZ-S(P))
-
- Species Reactivity: Human
- Type: Human scFv
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-223MZ-S(P)) (TAB-223MZ-S(P))
-
- Species Reactivity: Human
- Type: Human scFv
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-239MZ) (TAB-239MZ)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: IHC
Compare
- Rat Anti-DLL4 Recombinant Antibody (TAB-238MZ) (TAB-238MZ)
-
- Species Reactivity: Human
- Type: Rat IgG2a, κ
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody (TAB-237MZ) (TAB-237MZ)
-
- Species Reactivity: Human
- Type: Rat IgG2a, κ
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody (TAB-236MZ) (TAB-236MZ)
-
- Species Reactivity: Human
- Type: Rat IgG2a, κ
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody (TAB-235MZ) (TAB-235MZ)
-
- Species Reactivity: Human
- Type: Rat IgG2a, κ
- Application: ELISA, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-222MZ-F(E)) (TAB-222MZ-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-221MZ-F(E)) (TAB-221MZ-F(E))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-220MZ-F(E)) (TAB-220MZ-F(E))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-219MZ-F(E)) (TAB-219MZ-F(E))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-222MZ-S(P)) (TAB-222MZ-S(P))
-
- Species Reactivity: Human
- Type: Human scFv
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-221MZ-S(P)) (TAB-221MZ-S(P))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-220MZ-S(P)) (TAB-220MZ-S(P))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-219MZ-S(P)) (TAB-219MZ-S(P))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-222MZ) (TAB-222MZ)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: Block, FC, FuncS, Inhib
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-221MZ) (TAB-221MZ)
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, Neut
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-220MZ) (TAB-220MZ)
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, Neut
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-219MZ) (TAB-219MZ)
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, Neut, WB
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-218MZ-F(E)) (TAB-218MZ-F(E))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
Compare
- Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-217MZ-F(E)) (TAB-217MZ-F(E))
-
- Species Reactivity: Human
- Type: Chimeric antibody (mouse/human)
- Application: FC
Compare
- Mouse Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-216MZ-F(E)) (TAB-216MZ-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-218MZ-S(P)) (TAB-218MZ-S(P))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
Compare
- Mouse Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-217MZ-S(P)) (TAB-217MZ-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
Compare
- Mouse Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-216MZ-S(P)) (TAB-216MZ-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-217CL) (TAB-217CL)
-
- Species Reactivity: Human
- Type: Human IgG
- Application: WB, IHC, IF, FC, Inhib
Compare
- Rat Anti-DLL4 Recombinant Antibody (TAB-234MZ) (TAB-234MZ)
-
- Species Reactivity: Human
- Type: Rat IgG2a, κ
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody (TAB-233MZ) (TAB-233MZ)
-
- Species Reactivity: Human
- Type: Rat IgG2a, κ
- Application: ELISA, FC
Compare
- Rat Anti-DLL4 Recombinant Antibody (TAB-232MZ) (TAB-232MZ)
-
- Species Reactivity: Human
- Type: Rat IgG1, κ
- Application: ELISA, FC
Compare
-
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG2 - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-218MZ) (TAB-218MZ)
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, Neut
Compare
- Human Anti-DLL4 Recombinant Antibody (TAB-217MZ) (TAB-217MZ)
-
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: FC, FuncS
Compare
- Mouse Anti-DLL4 Recombinant Antibody (TAB-216MZ) (TAB-216MZ)
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, FuncS
Compare
- Min-23 scaffold protein anti-Human DLL4 (SMI-L141)
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- Scaffold Name: Min-23
- Target: DLL4
- Species Reactivity: Human
- Derivation: Ribosome display
Compare
- Anti-DLL4 Recombinant Antibody (TAB-744)
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- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: WB, Neut, ELISA, IF, IP, FuncS, FC
Compare
More Infomation
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