Human Anti-DLL4 Recombinant Antibody (TAB-221MZ)

Name: Human Anti-DLL4 Recombinant Antibody (TAB-221MZ)
SKU: TAB-221MZ
Rating: 5 (1 reviews)

CAT#: TAB-221MZ

This product is a recombinant human antibody that recognizes DLL4 (Delta-like ligand 4). The antibody was purified by affinity chromatography. It can be used for ELISA, FC, Neut and other applications. The antibody can inhibit the binding of human Notch-1 to DLL4 ligand. The IC₅₀ value of decreasing human DLL4-His bound to Notch 1-Fc is 3.72 nM.

Gene Expression

Normal Tissue Figure 1 IHC staining of human small intestine

Immunohistochemical staining of human small intestine shows strong membranous positivity in glandular cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_4_2_selected.jpg

Normal Tissue Figure 2 Colon

Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_9_3.jpg

Normal Tissue Figure 3 Liver

Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_8_4.jpg

Normal Tissue Figure 4 Kidney

Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_8_5.jpg

Normal Tissue Figure 5 Testis

Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_4_6.jpg

RNA Expression Figure 6 RNA cell line category: Group enriched (BJ hTERT+, HUVEC TERT2, SCLC-21H)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128917-DLL4

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Specifications

Immunogen
Human DLL4 protein

Host Species
Human

Derivation
Phage display library

Type
Human IgG

Specificity
Human

Species Reactivity
Human

Applications
ELISA, FC, Neut

Related Disease
Rheumatoid arthritis, systemic sclerosis, systemic Lupus erythematosus, atopic dermatitis, and the like

Product Property

Purity
>95% as determined by SDS-PAGE

Buffer
PBS

Preservative
No preservatives

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
DLL4; delta-like 4 (Drosophila); hdelta2; delta-like protein 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4

Gene ID
54567

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-221MZ.pdf

MSDS

MSDS - TAB-221MZ.pdf

COA

Certificate of Analysis Lookup

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