Anti-DLL4 Recombinant Antibody
CAT#: TAB-744
Recombinant human monoclonal antibody expressed in CHO binding to human DLL4. Anti-DLL4 Therapeutic Antibody is a human monoclonal antibody that binds to DLL4. It acts as an immunomodulator.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows strong membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_4_2_selected.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_9_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (BJ hTERT+, HUVEC TERT2, SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128917-DLL4
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG1 - kappa
- Species Reactivity
- Human
- Applications
- Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, IHC and most other immunological methods.
- Related Disease
- Cancers
Product Property
- Purity
- >95.0% as determined by analysis by RP-HPLC.
- Storage
- At -20°C for one year.
Target
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Functioning Well at Low Concentrations
This antibody yields good, efficient results even at low doses. It is very efficient and functions best in small amounts.
Simple Protocol Improvement
It was easy to optimize protocols with this antibody. The accurate information made it easy to achieve the best results without a lot of troubleshooting.
Excellent for Analyzing Pathways
I've found this antibody to be quite helpful in my route analysis research. It provides valuable insights by assisting in the identification of important proteins engaged in various pathways.
Q&As
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What's the proper way to prepare my samples for antibody labeling?
A: In order to decrease non-specific binding, samples should be processed in accordance with the particular guidelines of your assay, which usually include fixation, permeabilization (if necessary), and blocking.
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How do I titrate this antibody for my experiment?
A: To achieve the best signal-to-noise ratio, start with a wide range of dilutions (1:50, 1:100, 1:200, and 1:500), then test them simultaneously to determine the ideal concentration.
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Is there a recommended secondary antibody to pair with this one?
A: Indeed, it is advised that the secondary antibody be particular to the host species of the main antibody. For instance, employ an anti-mouse secondary if the main is mouse-derived.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "DLL4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-204 | Anti-Human DLL4 Recombinant Antibody (TAB-204) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG2 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-217CL | Human Anti-DLL4 Recombinant Antibody (TAB-217CL) | WB, IHC, IF, FC, Inhib | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-216MZ | Mouse Anti-DLL4 Recombinant Antibody (TAB-216MZ) | FC, FuncS | Mouse IgG |
| TAB-227MZ | Anti-Human DLL4 Recombinant Antibody (1C1) | ELISA, FC | |
| TAB-232MZ | Rat Anti-DLL4 Recombinant Antibody (TAB-232MZ) | ELISA, FC | Rat IgG1, κ |
| TAB-233MZ | Rat Anti-DLL4 Recombinant Antibody (TAB-233MZ) | ELISA, FC | Rat IgG2a, κ |
| TAB-234MZ | Rat Anti-DLL4 Recombinant Antibody (TAB-234MZ) | ELISA, FC | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-217MZ | Human Anti-DLL4 Recombinant Antibody (TAB-217MZ) | FC, FuncS | Chimeric (mouse/human) IgG |
| TAB-217MZ-S(P) | Mouse Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-217MZ-S(P)) | FC | Mouse scFv |
| TAB-217MZ-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-217MZ-F(E)) | FC | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-218MZ | Human Anti-DLL4 Recombinant Antibody (TAB-218MZ) | ELISA, FC, Neut | Human IgG |
| TAB-219MZ | Human Anti-DLL4 Recombinant Antibody (TAB-219MZ) | ELISA, FC, Neut, WB | Human IgG |
| TAB-220MZ | Human Anti-DLL4 Recombinant Antibody (TAB-220MZ) | ELISA, FC, Neut | Human IgG |
| TAB-221MZ | Human Anti-DLL4 Recombinant Antibody (TAB-221MZ) | ELISA, FC, Neut | Human IgG |
| TAB-222MZ | Human Anti-DLL4 Recombinant Antibody (TAB-222MZ) | Block, FC, FuncS, Inhib | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-707CQ | Hamster Anti-Dll4 Recombinant Antibody (clone HMD4-2) | Block | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4140 | Hi-Affi™ Rabbit Anti-DLL4 Recombinant Antibody (clone SI213DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0203-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0203-CN) | ELISA, WB, FC, IP | Human IgG1 |
| HPAB-0204-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0204-CN) | ELISA, WB, FC, IP | Human IgG1 |
| HPAB-0205-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0205-CN) | ELISA, WB, FC, IP | Human IgG4 |
| HPAB-0206-CN | Mouse Anti-DLL4 Recombinant Antibody (HPAB-0206-CN) | ELISA, WB, FC, IHC, IF, ICC | Mouse IgG2 |
| HPAB-0208-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0208-CN) | ELISA, WB, FC, IHC, IF, ICC | Humanized IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0203-CN-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0203-CN-F(E)) | ELISA, WB, FC, IP | Human Fab |
| HPAB-0207-CN-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0207-CN-F(E)) | ELISA, WB, FC, IHC, IF, ICC | Chimeric (mouse/human) Fab |
| HPAB-0152-LSX-F(E) | Mouse Anti-DLL4 Recombinant Antibody (clone 21H3); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0154-LSX-F(E) | Mouse Anti-DLL4 Recombinant Antibody (clone 9G8); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0156CQ-F(E) | Human Anti-DLL4 Recombinant Antibody Fab Fragment (HPAB-0156CQ-F(E)) | ELISA, FC, IHC, Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0152-LSX-S(P) | Mouse Anti-DLL4 Recombinant Antibody (clone 21H3); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0154-LSX-S(P) | Mouse Anti-DLL4 Recombinant Antibody (clone 9G8); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0155-LSX-S(P) | Mouse Anti-DLL4 Recombinant Antibody (clone 2H10); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0156CQ-S(P) | Human Anti-DLL4 Recombinant Antibody scFv Fragment (HPAB-0156CQ-S(P)) | ELISA, FC, IHC, Block | Human scFv |
| HPAB-0211-WJ-S(P) | Mouse Anti-DLL4 Recombinant Antibody (clone MMGZ01); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-204 | Afuco™ Anti-DLL4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-204) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1512-FY | Recombinant Llama Anti-DLL4 Single Domain Antibody (HPAB-1512-FY) | Block, ELISA, FC | Llama VHH |
| HPAB-1513-FY | Recombinant Llama Anti-DLL4 Single Domain Antibody (HPAB-1513-FY) | Block, ELISA, FC | Llama VHH |
| HPAB-1514-FY | Recombinant Llama Anti-DLL4 Single Domain Antibody (HPAB-1514-FY) | Block, ELISA, FC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY79 | AbPlus™ Anti-DLL4 Magnetic Beads (VS-0424-XY79) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY100 | Human Anti-DLL4 (clone 21H3RK) scFv-Fc Chimera | FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC215 | Recombinant Anti-DLL4 Vesicular Antibody, EV Displayed (VS-0425-YC215) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2018 | Anti-DLL4 Immunohistochemistry Kit | IHC |
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