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ITGAE

Anti-ITGAE Products
- Anti-human ITGAE Fab Fragment (3G6) (TAB-742LC-F(E))
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- Application: ELISA, FC
- Anti-human ITGAE Fab Fragment (5E4) (TAB-741LC-F(E))
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- Application: ELISA, FC
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- Application: ELISA, FC
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, FC
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: FC
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- Application: ELISA, FC
- Anti-human ITGAE scFv Fragment (5E4 (IgG1)) (TAB-744LC-S(P))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, FC
- Anti-human ITGAE scFv Fragment (3G6 (IgG1)) (TAB-745LC-S(P))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC
- Recombinant Rat Anti-ITGAE Antibody (M290) (FN-104CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2a
- Application: IF, Neut, FC
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- Species Reactivity: Mouse
- Type: Armenian hamster IgG
- Application: FC, FuncS, IHC-Fr
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- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: FC, FuncS, IHC, IP
- Anti-human ITGAE Fab Fragment (5E4 (IgG1)) (TAB-744LC-F(E))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, FC
- Anti-human ITGAE Fab Fragment (3G6 (IgG1)) (TAB-745LC-F(E))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, FC, IHC, IP
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- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Mouse Anti-ITGAE Recombinant Antibody (clone OX62) (FAMAB-1581CQ)
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- Species Reactivity: Rat
- Type: Mouse IgG1
- Application: Depletion, IP, MACS, WB, FC, IF, IHC-Fr
- Mouse Anti-ITGAE Antibody (clone OX62), mRNA (FAMAB-1581CQ-mRNA)
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- Species Reactivity: Rat
- Rat Anti-Itgae Antibody (clone M290), mRNA (AGTO-G046S-mRNA)
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- Species Reactivity: Mouse
- Human Anti-ITGAE Antibody, mRNA (TAB-458CL-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC
- Recombinant Rat Anti-Itgae Antibody (MAB0828) (NEUT-1558CQ)
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- Species Reactivity: Mouse
- Type: IgG2
- Application: BL, FC, IHC-Fr, IP
- Anti-Itgae immunotoxin M290 (IgG)-Sap (AGTO-G046S)
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- Species Reactivity: Mouse
- Application: Cytotoxicity assay, Function study
- Anti-Human ITGAE Recombinant Antibody (TAB-458CL)
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- Species Reactivity: Human
- Type: Antibody
- Mouse Anti-NHP ITGAE Recombinant Antibody (clone 2G5.1) (VS-1024-XY71)
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- Species Reactivity: Cynomolgus monkey, Human, Non-human primate, Rhesus monkey
- Type: Mouse IgG2a
- Application: IHC, FC
- Anti-human ITGAE Fab Fragment (8D5) (TAB-743LC-F(E))
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- Application: ELISA, FC
- Anti-human ITGAE scFv Fragment (5E4) (TAB-741LC-S(P))
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- Application: ELISA, FC
- Anti-human ITGAE scFv Fragment (3G6) (TAB-742LC-S(P))
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- Application: ELISA, FC
- Anti-human ITGAE scFv Fragment (8D5) (TAB-743LC-S(P))
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- Application: ELISA, FC
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- Application: ELISA, FC
- Anti-CD103 (clone M290)-MCC-DM1 ADC (ADC-091LZY)
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- Target: CD103
- Linker: MCC (4-(Nmaleimidomethyl)cyclohexane-1 carboxylate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Chicken Anti-ITGAE Polyclonal IgY (BRD-0296MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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- Target: ITGAE
- Host Animal: Human
- Application: ELISA, FC, Cell-uptake
- Anti-ITGAE Immunohistochemistry Kit (VS-0525-XY3638)
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- Species Reactivity: Human
- Target: ITGAE
- Application: IHC
- Anti-Human ITGAE Immunohistochemistry Kit (VS-0525-XY3639)
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- Species Reactivity: Human, Monkey
- Target: ITGAE
- Application: IHC
- Anti-CD103 (clone M290)-mc-vc-PABc-MMAE ADC (ADC-089LZY)
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- Target: CD103
- Linker: mc-VC-PABc(maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE(monomethyl auristatin E)
- Anti-CD103 (clone M290)-mc-MMAF ADC (ADC-090LZY)
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- Target: CD103
- Linker: mc(maleimidocaproyl)
- Drug: MMAF(monomethyl auristatin F)
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.
Protein class
CD markers
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Low cell type specificity
Immune cell specificity
Immune cell enhanced (memory CD8 T-cell)
Cell line specificity
Cell line enriched (MOLT-4)
Interaction
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chains linked by a disulfide bond. Alpha-E associates with beta-7.
Molecular function
Integrin, Receptor
More Types Infomation