Anti-Human VTCN1 Recombinant Antibody scFv Fragment (12E1)

Name: Anti-Human VTCN1 Recombinant Antibody scFv Fragment (12E1)
SKU: TAB-1124CL-S(P)
Rating: 5 (1 reviews)

CAT#: TAB-1124CL-S(P)

The anti-B7-H4 antibiody specifically binds B7-H4 also known as O8E, the antibody can be used in the treatment of cancer, such as ovarian cancer, lung cancer and breast cancer.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line MCF7

Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane & cell junctions.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/1356_C9_3_selected.jpg

Normal Tissue Figure 2 IHC staining of human breast

Immunohistochemical staining of human breast shows moderate membranous positivity in glandular cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/ihc_selected.jpg

Normal Tissue Figure 3 Colon

Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_9_3.jpg

Normal Tissue Figure 4 Kidney

Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_8_5.jpg

Normal Tissue Figure 5 Testis

Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_4_6.jpg

Normal Tissue Figure 6 Breast

Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_B_3_4.jpg

Normal Tissue Figure 7 Lymph node

Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_7_8.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enriched (SK-BR-3)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134258-VTCN1

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Specifications

Host Species
Human

Type
Fully human antibody

Specificity
Human

Clone
12E1

Related Disease
Ovarian cancer, Lung cancer, Breast cancer

Target

Alternative Names
VTCN1; V-set domain containing T cell activation inhibitor 1; B7X; B7H4; B7S1; B7-H4; B7h. 5; VCTN1; PRO129

Gene ID
79679

UniProt ID
Q7Z7D3

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-1124CL-S(P).pdf

MSDS

MSDS - TAB-1124CL-S(P).pdf

COA

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