Anti-Human VTCN1 Recombinant Antibody (2F9) (CAT#: TAB-1123CL)

Name: Anti-Human VTCN1 Recombinant Antibody (2F9)
SKU: TAB-1123CL
Rating: 5 (1 reviews)

The anti-B7-H4 antibiody specifically binds B7-H4 also known as O8E, the antibody can be used in the treatment of cancer, such as ovarian cancer, lung cancer and breast cancer.

Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

We require custom production

Published Data
Gene Expression
Datasheet
MSDS
COA

ADCC

Figure 1 The results of antibody dependent cellular cytotoxicity (ADCC) assays demonstrating that human monoclonal anti-O8E antibodies kill O8E transfected SKOV3 cells in an ADCC dependent manner.

Figure 1 The results of antibody dependent cellular cytotoxicity (ADCC) assays demonstrating that human monoclonal anti-O8E antibodies kill O8E transfected SKOV3 cells in an ADCC dependent manner.

ADCC

Figure 2 The results of antibody dependent cellular cytotoxicity (ADCC) assays demonstrating that human monoclonal anti-O8E antibodies kill human breast cancer cell line SKBR3 in a concentration and ADCC dependent manner.

Subcellular Location

Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/1356_C9_3_selected.jpg

Normal Tissue

Figure 2 IHC staining of human breast
(Immunohistochemical staining of human breast shows moderate membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/ihc_selected.jpg

Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_9_3.jpg

Figure 4 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_8_5.jpg

Figure 5 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_4_6.jpg

Figure 6 Breast
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_B_3_4.jpg

Figure 7 Lymph node
(Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54200/147470_A_7_8.jpg

RNA Expression

Figure 8 RNA cell line category: Cell line enriched (SK-BR-3)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134258-VTCN1

Datasheet

MSDS

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Host Species
Human

Type
Fully human antibody

Specificity
Human

Clone
2F9

Applications
ADCC

Related Disease
Ovarian cancer, Lung cancer, Breast cancer

Applications

Application Notes
This antibody has been tested for use in Antibody-dependent Cellular Cytotoxicity Assay.

Target

Alternative Names
VTCN1; V-set domain containing T cell activation inhibitor 1; B7X; B7H4; B7S1; B7-H4; B7h. 5; VCTN1; PRO129

Gene ID
79679

UniProt ID
Q7Z7D3

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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CAT	Product Name	Application	Type
MOB-2216z	Mouse Anti-VTCN1 Recombinant Antibody (clone 21A2)	WB, ELISA	Mouse IgG1
TAB-1120CL	Human Anti-VTCN1 Recombinant Antibody (TAB-1120CL)	FuncS	Human IgG
HPAB-0305-CN	Mouse Anti-VTCN1 Recombinant Antibody (clone 5F6)	ELISA, FC, IHC	Mouse IgG
MRO-1675-CN	Rabbit Anti-VTCN1 Polyclonal Antibody (MRO-1675-CN)	WB, IF, IHC, FC	Rabbit IgG
MRO-1676-CN	Rabbit Anti-VTCN1 Polyclonal Antibody (MRO-1676-CN)	WB, IF, IHC, FC	Rabbit IgG

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CAT	Product Name	Application	Type
TAB-1110CL	Human Anti-VTCN1 Recombinant Antibody (TAB-1110CL)	ELISA, FC	Chimeric (Mouse/Human) IgG4
TAB-1112CL	Human Anti-VTCN1 Recombinant Antibody (TAB-1112CL)	ELISA, FC	Chimeric (Mouse/Human) IgG4
TAB-1110CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1110CL-S(P))	ELISA, FC	Human scFv
TAB-1112CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1112CL-S(P))	ELISA, FC	Human scFv
TAB-1114CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1114CL-S(P))	ELISA, FC	Human scFv

CAT	Product Name	Application	Type
TAB-1101CL-S(P)	Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1101CL-S(P))	ELISA, WB, FC, FuncS	Mouse scFv
TAB-1109CL-S(P)	Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1109CL-S(P))	ELISA, FC	Mouse scFv
TAB-1111CL-S(P)	Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1111CL-S(P))	ELISA, FC	Mouse scFv
TAB-1113CL-S(P)	Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1113CL-S(P))	ELISA, FC	Mouse scFv
TAB-1115CL-S(P)	Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1115CL-S(P))	ELISA	Mouse scFv

CAT	Product Name	Application	Type
TAB-1102CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1102CL-S(P))	ELISA	Humanized scFv
TAB-1103CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1103CL-S(P))	ELISA	Humanized scFv
TAB-1104CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1104CL-S(P))	ELISA	Humanized scFv
TAB-1105CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1105CL-S(P))	ELISA	Humanized scFv
TAB-1106CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1106CL-S(P))	ELISA	Humanized scFv

CAT	Product Name	Application	Type
TAB-1117CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1117CL-S(P))	ELISA, FC, FuncS	Human scFv
TAB-1118CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1118CL-S(P))	ELISA, FC, FuncS	Human scFv
TAB-1119CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1119CL-S(P))	ELISA, FC, FuncS	Human scFv
TAB-1121CL-S(P)	Anti-Human VTCN1 Recombinant Antibody scFv Fragment (11G1)	ELISA	Fully human antibody
TAB-1122CL-S(P)	Anti-Human VTCN1 Recombinant Antibody scFv Fragment (2A7)	ELISA	Fully human antibody

CAT	Product Name	Application	Type
TAB-1120CL-S(P)	Human Anti-VTCN1 Recombinant Antibody; scFv Fragment (TAB-1120CL-S(P))	FuncS	Human scFv
HPAB-0305-CN-S(P)	Mouse Anti-VTCN1 Recombinant Antibody (clone 5F6); scFv Fragment	ELISA, FC, IHC	Mouse scFv
HPAB-0306-CN-S(P)	Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (HPAB-0306-CN-S(P))	ELISA, FC, IHC, IF	Mouse scFv
HPAB-0307-CN-S(P)	Mouse Anti-VTCN1 Recombinant Antibody; scFv Fragment (HPAB-0307-CN-S(P))	ELISA, FC, IHC, IF	Mouse scFv
HPAB-N0297-YC-S(P)	Mouse Anti-VTCN1 Recombinant Antibody (clone B7H4/1E10); scFv Fragment	ELISA, WB	Mouse scFv

CAT	Product Name	Application	Type
HPAB-0305-CN-F(E)	Mouse Anti-VTCN1 Recombinant Antibody (clone 5F6); Fab Fragment	ELISA, FC, IHC	Mouse Fab
HPAB-0306-CN-F(E)	Mouse Anti-VTCN1 Recombinant Antibody; Fab Fragment (HPAB-0306-CN-F(E))	ELISA, FC, IHC, IF	Mouse Fab
HPAB-0307-CN-F(E)	Mouse Anti-VTCN1 Recombinant Antibody; Fab Fragment (HPAB-0307-CN-F(E))	ELISA, FC, IHC, IF	Mouse Fab
HPAB-0335CQ-F(E)	Human Anti-VTCN1 Recombinant Antibody Fab Fragment (HPAB-0335CQ-F(E))	ELISA, FC	Human Fab
HPAB-0336CQ-F(E)	Human Anti-VTCN1 Recombinant Antibody Fab Fragment (HPAB-0336CQ-F(E))	ELISA, FC	Human Fab