


ALK

Anti-ALK Products
- Mouse Anti-ALK Recombinant Antibody (clone 26D9) (MOB-1446z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, FC, ICC, IF
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- Derivation: Mouse
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Mouse Anti-ALK Recombinant Antibody (clone BLK2) (MOB-0296MZ)
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- Species Reactivity: Human
- Type: Mouse IgG3
- Application: IHC
- Human Anti-ALK Antibody, mRNA (TAB-032CL-mRNA)
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- Species Reactivity: Human
- Mouse Anti-ALK Recombinant Antibody (VS-0224-XY7) (VS-0224-XY7)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, IF, ICC
- Mouse Anti-ALK/p80 Recombinant Antibody (VS3-FY2624) (VS3-FY2624)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, FC, ELISA
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- Class: Class I
- Antigen: Mutant anaplastic lymphoma kinase
- Antigen Species: Human
- Peptide: SLAMLDLLHV
- Conjugate: Unlabeled, Biotin, R-PE, APC
- Mouse Anti-ALK Recombinant Antibody (HPAB-1826LY) (HPAB-1826LY)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody (HPAB-1817LY) (HPAB-1817LY)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody (HPAB-1818LY) (HPAB-1818LY)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody (HPAB-1819LY) (HPAB-1819LY)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody (HPAB-1820LY) (HPAB-1820LY)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, WB, FC, Agonist
- Mouse Anti-ALK Recombinant Antibody (HPAB-1821LY) (HPAB-1821LY)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody (HPAB-1822LY) (HPAB-1822LY)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: FC, WB, ELISA, Inhib, FuncS
- Mouse Anti-ALK Recombinant Antibody (HPAB-1823LY) (HPAB-1823LY)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody (HPAB-1824LY) (HPAB-1824LY)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody (HPAB-1825LY) (HPAB-1825LY)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody (HPAB-0139-YC) (HPAB-0139-YC)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, WB, FC, Agonist
- Mouse Anti-ALK Recombinant Antibody (HPAB-0140-YC) (HPAB-0140-YC)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, FC, WB
- Mouse Anti-ALK Recombinant Antibody (HPAB-0141-YC) (HPAB-0141-YC)
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- Species Reactivity: Human
- Type: Mouse IgG, κ
- Application: ELISA, FC, RIA, Inhib
- Mouse Anti-ALK Recombinant Antibody (clone D10) (HPAB-0143-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC, Stim
- Mouse Anti-ALK Recombinant Antibody (HPAB-0138-YC) (HPAB-0138-YC)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: ELISA, FC, WB, Inhib
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-0138-YC-S(P)) (HPAB-0138-YC-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, FC, WB
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-0139-YC-S(P)) (HPAB-0139-YC-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, FC, WB
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-1824LY-F(E)) (HPAB-1824LY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-1825LY-F(E)) (HPAB-1825LY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-1826LY-F(E)) (HPAB-1826LY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-1818LY-F(E)) (HPAB-1818LY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-1819LY-F(E)) (HPAB-1819LY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-1820LY-F(E)) (HPAB-1820LY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-1821LY-F(E)) (HPAB-1821LY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-1822LY-F(E)) (HPAB-1822LY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-1823LY-F(E)) (HPAB-1823LY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-0141-YC-F(E)) (HPAB-0141-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, RIA
- Mouse Anti-ALK Recombinant Antibody (clone D10); Fab Fragment (HPAB-0143-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, Stim
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, WB, FuncS
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, WB
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, WB
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-1817LY-F(E)) (HPAB-1817LY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-0140-YC-S(P)) (HPAB-0140-YC-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, FC, WB
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-0141-YC-S(P)) (HPAB-0141-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, RIA
- Mouse Anti-ALK Recombinant Antibody (clone D10); scFv Fragment (HPAB-0143-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, Stim
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-0138-YC-F(E)) (HPAB-0138-YC-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, FC, WB
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-0139-YC-F(E)) (HPAB-0139-YC-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, FC, WB
- Mouse Anti-ALK Recombinant Antibody; Fab Fragment (HPAB-0140-YC-F(E)) (HPAB-0140-YC-F(E))
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, FC, WB
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-1817LY-S(P)) (HPAB-1817LY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-1818LY-S(P)) (HPAB-1818LY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-1819LY-S(P)) (HPAB-1819LY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-1820LY-S(P)) (HPAB-1820LY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-1821LY-S(P)) (HPAB-1821LY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-1822LY-S(P)) (HPAB-1822LY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-1823LY-S(P)) (HPAB-1823LY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-1824LY-S(P)) (HPAB-1824LY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-1825LY-S(P)) (HPAB-1825LY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Mouse Anti-ALK Recombinant Antibody; scFv Fragment (HPAB-1826LY-S(P)) (HPAB-1826LY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, WB, FC
- Anti-Human ALK Recombinant Antibody (TAB-032CL)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Antibody
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Antibody Host: Mouse
- Antibody Reactivity: Human
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FCM
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ICC, FCM
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- Species Reactivity: Human
- Target: ALK
- Host Animal: Mouse
- Application: ELISA, FC, Stim, Cell-uptake
- Anti-ALK Immunohistochemistry Kit (VS-0525-XY319)
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- Species Reactivity: Human
- Target: ALK
- Application: IHC
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For Research Use Only. Not For Clinical Use.
At Creative Biolabs, our advanced platforms enable us to deliver comprehensive antibody solutions that meet our clients' specific needs, thereby supporting your meaningful research and discovery efforts globally. We strive to empower our clients to achieve their scientific goals quickly and precisely by prioritizing exceptional value and providing unparalleled technical support. Trust Creative Biolabs to be your partner in making ground-breaking research discoveries.
ALK: A Prominent Target in Cancer Therapy
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase belonging to the insulin receptor superfamily. The activation of this gene is crucial in the pathogenesis of various human malignancies, including anaplastic large-cell lymphoma, neuroblastoma, inflammatory myofibroblastic tumors, and lung cancer. Given its limited expression in adult tissues, targeting ALK in cancer treatment is promising, with the expectation of minimal toxic effects. This makes ALK an attractive therapeutic target for developing novel cancer treatments.
Alternative Names
Anaplastic lymphoma kinase; CD246; NBLST3; anaplastic lymphoma receptor tyrosine kinase; ALK receptor tyrosine kinase; ALK (gene); anaplastic lymphoma kinase (Ki-1); Ki-1; NBLST3; Tcrz ALK CD246; NBLST3 ALK receptor tyrosine kinase ALK tyrosine kinase receptor.
Background
Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins
Intracellular, Membrane (different isoforms)
Group enriched (Oligodendrocyte precursor cells, Inhibitory neurons)
Not detected in immune cells
Cell line enriched (SH-SY5Y)
Homodimer; homodimerizes following heparin- and ligand-binding (PubMed:16317043, PubMed:25605972, PubMed:34646012, PubMed:34819673). Interacts with CBL, IRS1, PIK3R1 and PLCG1 (PubMed:15226403). Interacts with FRS2 and SHC1 (PubMed:15226403, PubMed:16878150, PubMed:17274988). Interacts with PTN and MDK (PubMed:11278720, PubMed:12122009).
Kinase, Receptor, Transferase, Tyrosine-protein kinase
Anti-ALK Recombinant Antibody Products
Leveraging our advanced antibody engineering platform in Shirley, we have developed a series of innovative and effective anti-ALK recombinant antibody products. Meanwhile, we provide these premium products for clients around the world to aid your challenging antibody discovery and development projects. Please click the provided link to get more details of your interested products.
Cat. No. | Product Name | Target Species | Host Species | Applications |
HPAB-1826LY | Mouse Anti-ALK Recombinant Antibody | Human, Mouse | Mouse IgG | ELISA, WB, FC |
HPAB-1825LY | Mouse Anti-ALK Recombinant Antibody | Human, Mouse | Mouse IgG | ELISA, WB, FC |
HPAB-1824LY | Mouse Anti-ALK Recombinant Antibody | Human, Mouse | Mouse IgG | ELISA, WB, FC |
HPAB-1823LY | Mouse Anti-ALK Recombinant Antibody | Human, Mouse | Mouse IgG | ELISA, WB, FC |
HPAB-1822LY | Mouse Anti-ALK Recombinant Antibody | Human, Mouse | Mouse IgG | FC, WB, ELISA, Inhib, FuncS |
NS-004CN | Human Anti-ALK Recombinant Antibody (clone ESBA521) | Human | Human IgG | ELISA, WB, FuncS |
Creative Quality Control
We are dedicated to empowering the biopharmaceutical community by fostering innovation in research and development with top-tier product quality and outstanding support. Customer satisfaction is at the core of our operations, which is why we meticulously maintain a robust quality management system. This ensures that our products consistently meet and often surpass industry standards. By doing so, we enhance the efficiency of the drug development process and provide exceptional value to our customers.
Customer Reviews

Mouse Anti-ALK Recombinant Antibody (clone 26D9) (CAT#: MOB-1446z)

Mouse Anti-ALK Recombinant Antibody (HPAB-1817LY) (CAT#: HPAB-1817LY)

Hi-Affi™ Rabbit Anti-ALK Recombinant Antibody (clone DS147AB) (CAT#: MOR-0147)
Anti-ALK Recombinant Antibody Production
Our advanced serum-free mammalian cell expression platform provides an end-to-end solution from gene synthesis to the scalable production of high-quality anti-ALK recombinant antibodies. With over five years devoted to refining our processes, we offer cost-efficient and swift production, ensuring rapid delivery of various antibody quantities.
Featured Anti-ALK Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-ALK recombinant antibody production.
Fig.2 Gram-scale anti-ALK recombinant antibody production.
Anti-ALK Recombinant Antibody Modalities
Creative Biolabs prides itself on providing a wide array of cutting-edge recombinant antibodies tailored for researchers. Our portfolio of anti-ALK antibodies is available in multiple formats, including full-length, Fab, and scFv. Backed by our profound knowledge and years of experience in antibody engineering, we are well-equipped to offer bespoke solutions that cater to your unique research requirements.
Fig.3 Full-Length Anti-ALK Recombinant Antibody Production and Modalities
ALK-Targeted Drug Information
Table 1. ALK-targeted drug information.
Company | Highest Phase | Classification | Condition |
Celldex Therapeutics (Originator) | Preclinical |
Cancer Immunotherapy Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) |
Neuroblastoma |
Celldex Therapeutics (Originator) | Preclinical |
Cancer Immunotherapy Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) (Second-Generation CAR) |
Neuroblastoma |
Universita degli Studi di Torino (Originator) | Preclinical |
Cancer Immunotherapy Cancer Vaccines DNA Vaccines |
Neuroblastoma |
AIST (Originator) | Preclinical |
Oligopeptides, less than 10 AA Peptide-Drug Conjugates |
Cancer |
Co-D Therapeutics University of Wisconsin-Madison (Originator) Wisconsin Alumni Research Foundation (Originator) |
Preclinical |
Fixed-Dose Combinations Micelles Microparticles Natural Products Rapamycins Taxanes |
Angiosarcoma Cancer, breast Cancer, lung (non-small cell) (NSCLC) |
CovX (Originator) | Preclinical | Immunoconjugates | Cancer, breast |
Istituto Giannina Gaslini (Originator) | Preclinical |
Nanoparticles Small Interfering RNA (SiRNAs) |
Neuroblastoma |
Kuur Therapeutics Novartis (Originator) |
Preclinical |
Cancer Immunotherapy Monoclonal Antibodies |
Cancer Glioblastoma |
Children's Hospital of Philadelphia (Originator) University of Pittsburgh (Originator) |
Biological Testing |
Cancer Immunotherapy Chimeric Antigen Receptor-Modified T Cells (CAR T Cells) |
Neuroblastoma |
Children's Hospital of Philadelphia (Originator) University of Pittsburgh (Originator) |
Biological Testing |
Bispecific Antibody Fusions Cancer Immunotherapy Fc Fusion Proteins Polypeptides, from 41 AA Single-Chain V-Domain Antibody Fragment (scFv) Single-Domain Antibodies |
Neuroblastoma |
(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)
If you would like to learn more about our anti-ALK recombinant antibody products, please feel free to get in touch with us at your convenience.