Anti-Human CD3 Recombinant Antibody (VH2/VK3) (CAT#: TAB-090LC)

Recombinant monoclonal antibody to CD3. VH2/VK3 is a humanized antibody that can be potentially used in the treatment of autoimmune disorders, infectious diseases and transplant rejection.

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  • Published Data
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FC

Figure 1 Quantitative binding competition of humanized mAb variants with labeled OKT to Jurkat cells.

Figure 1 Quantitative binding competition of humanized mAb variants with labeled OKT to Jurkat cells.

FuncS

Figure 2 T-cell proliferation assay of humanized MAbs

Figure 2 T-cell proliferation assay of humanized MAbs

FuncS

Figure 3 IL-2 secretion assay of selected humanized mutants.

Figure 3 IL-2 secretion assay of selected humanized mutants.

Figure 4 Stability study—comparison between humanized variant mAbs and OKT.

Figure 4 Stability study—comparison between humanized variant mAbs and OKT.


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Clone
  • VH2/VK3
  • Applications
  • ELISA, FC, FuncS
  • Related Disease
  • Autoimmune Disorders, infectious diseases, and Transplant rejection

Applications

  • Application Notes
  • This antibody has been tested for use in Flow Cytometry and Functional Assay. Please see the Published Data for further information.

Target

  • Alternative Names
  • CD3; CD3 T-Cell Co-receptor;CD3D; CD3E; CD3G

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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TAB-0417CL Chimeric Anti-Human CD3 Recombinant Antibody ELISA, FC, FuncS Chimeric (mouse/human)
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TAB-0417CL-F(E) Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment ELISA, FC, FuncS Chimeric (mouse/human)
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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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