Anti-Human CD3 Recombinant Antibody (VH2/VK3) (CAT#: TAB-090LC)

Recombinant monoclonal antibody to CD3. VH2/VK3 is a humanized antibody that can be potentially used in the treatment of autoimmune disorders, infectious diseases and transplant rejection.


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FC

Figure 1 Quantitative binding competition of humanized mAb variants with labeled OKT to Jurkat cells.

Figure 1 Quantitative binding competition of humanized mAb variants with labeled OKT to Jurkat cells.

FuncS

Figure 2 T-cell proliferation assay of humanized MAbs

Figure 2 T-cell proliferation assay of humanized MAbs

FuncS

Figure 3 IL-2 secretion assay of selected humanized mutants.

Figure 3 IL-2 secretion assay of selected humanized mutants.

Figure 4 Stability study—comparison between humanized variant mAbs and OKT.

Figure 4 Stability study—comparison between humanized variant mAbs and OKT.


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Clone
  • VH2/VK3
  • Applications
  • ELISA, FC, FuncS
  • Related Disease
  • Autoimmune Disorders, infectious diseases, and Transplant rejection

Applications

  • Application Notes
  • This antibody has been tested for use in Flow Cytometry and Functional Assay. Please see the Published Data for further information.

Target

  • Alternative Names
  • CD3; CD3 T-Cell Co-receptor;CD3D; CD3E; CD3G

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone VH2/VK3"

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Chimeric Antibody

CAT Product Name Application Type
TAB-0417CL Chimeric Anti-Human CD3 Recombinant Antibody ELISA, FC, FuncS Chimeric (mouse/human)
TAB-0417CL-S(P) Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment ELISA, FC, FuncS Chimeric (mouse/human)
TAB-071LC Anti-Human CD3 Recombinant Antibody ELISA Chimeric antibody (mouse/human)
TAB-071LC-F(E) Anti-Human CD3 Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)
TAB-072LC-F(E) Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment ELISA Chimeric antibody (mouse/human)

Humanized Antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-339CQ Mouse Anti-CD3 Recombinant Antibody (clone SPV-T3b) FC, Block, IHC-Fr, IF, WB Mouse IgG2a
NEUT-340CQ Mouse Anti-CD3 Recombinant Antibody (clone UCHT1) FC, IHC-Fr, IHC-P, ICC, IP, WB, Activ, Block Mouse IgG1, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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