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    Anti-CD30 monoclonal antibody (MDX-1401) (CAT#: Gly-009CL)

    MDX-1401 is a fully human, non-fucosylated antibody that targets CD30, a marker for activated lymphocytes that is present on malignant cells of HL as well as other CD30-expressing cancers.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line HDLM-2
    Figure 1 IF staining of human cell line HDLM-2
    (Immunofluorescent staining of human cell line HDLM-2 shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14823/1962_A8_5_selected.jpg
    Figure 2 IHC staining of human testis
    Figure 2 IHC staining of human testis
    (Immunohistochemical staining of human testis shows strong cytoplasmic positivity in a subset of cells in seminiferus ducts.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32081/ihc_selected.jpg
    Figure 3 IHC staining of human tonsil
    Figure 3 IHC staining of human tonsil
    (Immunohistochemical staining of human tonsil shows leukocyte positivity in germinal center.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32082/ihc_selected.jpg
    Figure 4 IHC staining of human tonsil
    Figure 4 IHC staining of human tonsil
    (Immunohistochemical staining of human tonsil shows cytoplasmic positivity in leukocytes.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16/ihc_selected.jpg
    Figure 5 IF staining of human cell line EFO-21
    Figure 5 IF staining of human cell line EFO-21
    (Immunofluorescent staining of human cell line EFO-21 shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14823/1907_B6_1_blue_red_green.jpg
    Figure 6 IF staining of human cell line K-562
    Figure 6 IF staining of human cell line K-562
    (Immunofluorescent staining of human cell line K-562 shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14823/1993_D10_4_blue_red_green.jpg
    Normal Tissue
    Figure 7 Colon
    Figure 7 Colon
    (Endothelial cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16/165_A_8_3.jpg
    Figure 8 Appendix
    Figure 8 Appendix
    (Glandular cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16/165_A_2_2.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enriched (HDLM-2)
    Figure 9 RNA cell line category: Cell line enriched (HDLM-2)
    (Cell lines ordered by descending RNA expression order.)
    * https://v21.proteinatlas.org/ENSG00000120949-TNFRSF8
    Figure 9 RNA cell line category: Cell line enriched (HDLM-2)
    Figure 9 RNA cell line category: Cell line enriched (HDLM-2)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120949-TNFRSF8

    Specifications

    • Type
    • Fully human Ab
    • Class
    • Antineoplastics; Monoclonal antibodies
    • Mechanism of action
    • CD30 antigen inhibitors; Immunostimulants

    References

    • Synonyms
    • Lymphoma therapies; MDX-1401

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    IgG Antibodies Human Antibodies Chimeric Antibodies Immunotoxins Humanized Antibodies Fc Glycosylation Antibodies Low- or Non-fucosylated Oligosaccharide Antibodies Chicken IgY Antibodies Blocking Antibodies Neutralizing Antibodies Rabbit Monoclonal Antibodies ScFv Antibodies Fab Antibodies ADCC Enhanced Antibodies Agonistic Antibodies ScFv-Fc Chimeras FC Reagents & Kits Extracellular Vesicle Antibodies IHC Kits & Antibodies Biparatopic Antibodies
    CAT Product Name Application Type
    MOB-1158z Mouse Anti-TNFRSF8 Recombinant Antibody (clone 19C10) WB, FC, FuncS Mouse IgG2b
    HPAB-0329-YC Mouse Anti-TNFRSF8 Recombinant Antibody (HPAB-0329-YC) ELISA, FC, Cyt, FuncS, Inhib Mouse IgG
    HPAB-0330-YC Human Anti-TNFRSF8 Recombinant Antibody (HPAB-0330-YC) ELISA, FC, Cyt, FuncS, Inhib Chimeric (mouse/human) IgG1, κ
    HPAB-0331-YC Mouse Anti-TNFRSF8 Recombinant Antibody (HPAB-0331-YC) ELISA, FC, Cyt, FuncS, Inhib Mouse IgG
    HPAB-0250-FY Recombinant Human Anti-TNFRSF8 Antibody F, IH Human IgG1

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    For Research Use Only. Not For Clinical Use.

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