This immunotoxin was achieved by conjugating/fusing the Anti-TNFRSF8 scFv to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to TNFRSF8 overexpressed malignant lymphoma cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of malignant lymphoma.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-144 | Anti-Human CD30 Recombinant Antibody (Iratumumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-153 | Chimeric (Mouse/Human) Anti-TNFRSF8 Recombinant Antibody (clone Brentuximab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Human IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G062E | Anti-TNFRSF8 immunotoxin Ki-3 (scFv)-PE | Cytotoxicity assay, Function study | |
AGTO-G062S | Anti-TNFRSF8 immunotoxin Ki-3 (scFv)-Sap | Cytotoxicity assay, Function study | |
AGTO-L041E | anti-TNFRSF8 immunotoxin Ber-H2 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L041R | anti-TNFRSF8 immunotoxin Ber-H2 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L041S | anti-TNFRSF8 immunotoxin Ber-H2 (IgG)-Sap | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-635CL | Human Anti-TNFRSF8 Recombinant Antibody (TAB-635CL) | ELISA | Human IgG |
TAB-103LC | Anti-Human TNFRSF8 Recombinant Antibody | WB, FC, ELISA | Humanized antibody |
TAB-103LC-S(P) | Anti-Human TNFRSF8 Recombinant Antibody scFv Fragment | WB, FC, ELISA | Humanized antibody |
TAB-103LC-F(E) | Anti-Human TNFRSF8 Recombinant Antibody Fab Fragment | WB, FC, ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-139LC | Recombinant Anti-Human TNFRSF8 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-139LC-1 | Recombinant Anti-Human TNFRSF8 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0597MZ | Chicken Anti-TNFRSF8 Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2165CQ | Hamster Anti-Tnfrsf8 Recombinant Antibody (clone mCD30.1) | FC, Stim, Costim, Block | Hamster IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2166CQ | Hamster Anti-Tnfrsf8 Recombinant Antibody (clone 2SH12-5F) | Neut, FC | Hamster IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3617 | Rabbit Anti-TNFRSF8 Recombinant Antibody (clone DS3617AB) | WB, IHC-P | Rabbit IgG |
MOR-3618 | Rabbit Anti-TNFRSF8 Recombinant Antibody (clone DS3618AB) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0329-YC | Mouse Anti-TNFRSF8 Recombinant Antibody (HPAB-0329-YC) | ELISA, FC, Cyt, FuncS, Inhib | Mouse IgG |
HPAB-0330-YC | Human Anti-TNFRSF8 Recombinant Antibody (HPAB-0330-YC) | ELISA, FC, Cyt, FuncS, Inhib | Chimeric (mouse/human) IgG1, κ |
HPAB-0331-YC | Mouse Anti-TNFRSF8 Recombinant Antibody (HPAB-0331-YC) | ELISA, FC, Cyt, FuncS, Inhib | Mouse IgG |
HPAB-0332-YC | Human Anti-TNFRSF8 Recombinant Antibody (HPAB-0332-YC) | FC, Cyt, FuncS | Human IgG1, κ |
HPAB-0333-YC | Human Anti-TNFRSF8 Recombinant Antibody (HPAB-0333-YC) | FC, Cyt, FuncS | Human IgG, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0329-YC-S(P) | Mouse Anti-TNFRSF8 Recombinant Antibody; scFv Fragment (HPAB-0329-YC-S(P)) | ELISA, FC, Cyt, FuncS | Mouse scFv |
HPAB-0330-YC-S(P) | Human Anti-TNFRSF8 Recombinant Antibody; scFv Fragment (HPAB-0330-YC-S(P)) | ELISA, FC, Cyt, FuncS | Mouse scFv |
HPAB-0325CQ-S(P) | Human Anti-TNFRSF8 Recombinant Antibody; scFv Fragment (HPAB-0325CQ-S(P)) | ELISA, FC, FuncS, Cyt | Humanized scFv |
HPAB-0459-WJ-S(P) | Mouse Anti-TNFRSF8 Recombinant Antibody; scFv Fragment (HPAB-0459-WJ-S(P)) | ELISA | Mouse scFv |
FAMAB-0358WJ-S(P) | Human Anti-TNFRSF8 Recombinant Antibody (clone AK30); scFv Fragment | ELISA, WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0329-YC-F(E) | Mouse Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0329-YC-F(E)) | ELISA, FC, Cyt, FuncS | Mouse Fab |
HPAB-0330-YC-F(E) | Human Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0330-YC-F(E)) | ELISA, FC, Cyt, FuncS | Human Fab |
HPAB-0331-YC-F(E) | Mouse Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0331-YC-F(E)) | ELISA, FC, Cyt, FuncS | Mouse Fab |
HPAB-0332-YC-F(E) | Human Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0332-YC-F(E)) | FC, Cyt | Human Fab |
HPAB-0333-YC-F(E) | Human Anti-TNFRSF8 Recombinant Antibody; Fab Fragment (HPAB-0333-YC-F(E)) | FC, Cyt, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-144 | Afuco™ Anti-TNFRSF8 ADCC Recombinant Antibody (Iratumumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
AFC-TAB-153 | Afuco™ Anti-TNFRSF8 ADCC Recombinant Antibody (Brentuximab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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