Human Anti-CD6 Recombinant Antibody (clone OX-126)
CAT#: NEUT-400CQ
This antibody is a human monoclonal antibody that binds specifically to CD6, and it can neutralize the bioactivity of CD6.
Gene Expression
Normal Tissue
Figure 1 High expression in lymph node.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2489/6144_A_8_8_val_selected.jpg
Normal Tissue
Figure 2 Low expression in cerebral cortex.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2489/6144_B_8_5_val_selected.jpg
Normal Tissue
Figure 3 Colon
Enterocytes - Mucosal lymphoid cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2489/6144_A_8_3.jpg
Normal Tissue
Figure 4 Lymph node
Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2489/6144_A_7_8.jpg
Normal Tissue
Figure 5 Tonsil
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2489/6144_A_5_8.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (JURKAT, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000013725-CD6
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Specifications
- Immunogen
- A fusion protein consisting of human CD6 domain 3 and rat CD4 domains 3 and 4.
- Host Species
- Human
- Type
- Human IgG1, κ
- Specificity
- Human CD6
- Species Reactivity
- Human
- Clone
- OX-126
- Applications
- FC, IHC, IF, FuncS, Depletion, Block
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Protein A affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "CD6"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-247 | Anti-Human CD6 Recombinant Antibody (TAB-247) | WB, IF, IP, Neut, FuncS, ELISA, FC | IgG1 - kappa |
| TAB-325LC | Human Anti-CD6 Recombinant Antibody (TAB-325LC) | Cyt, FC | Humanized antibody |
| TAB-325LC-S(P) | Human Anti-CD6 Recombinant Antibody; scFv Fragment (TAB-325LC-S(P)) | FC, ELISA | Humanized scFv |
| TAB-325LC-F(E) | Human Anti-CD6 Recombinant Antibody; Fab Fragment (TAB-325LC-F(E)) | FC, ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-399CQ | Mouse Anti-CD6 Recombinant Antibody (clone OX-124) | Block | Mouse IgG1, κ |
| NEUT-401CQ | Rat Anti-Cd6 Recombinant Antibody (clone CBL311) | Block | Rat IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0573 | Hi-Affi™ Rabbit Anti-CD6 Recombinant Antibody (clone DS573AB) | IHC-P, IP, WB | Rabbit IgG |
| MOR-0574 | Hi-Affi™ Rabbit Anti-CD6 Recombinant Antibody (clone DS574AB) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-247 | Afuco™ Anti-CD6 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-247) | IF, IP, Neut, FuncS, ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0043-YC-S(P) | Human Anti-CD6 Recombinant Antibody; scFv Fragment (HPAB-N0043-YC-S(P)) | ELISA, FC | Human scFv |
| HPAB-0009-YJ-S(P) | Mouse Anti-CD6 Recombinant Antibody (clone IOR T1); scFv Fragment | FuncS, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0043-YC-F(E) | Human Anti-CD6 Recombinant Antibody; Fab Fragment (HPAB-N0043-YC-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-0009-YJ-F(E) | Mouse Anti-CD6 Recombinant Antibody (clone IOR T1); Fab Fragment | FuncS, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1643CQ | Mouse Anti-CD6 Recombinant Antibody (clone OX52) | IP, FC, IHC-Fr | Mouse IgG2a |
| FAMAB-1644CQ | Mouse Anti-CD6 Recombinant Antibody (clone OX129) | FC, IF | Mouse IgG2a |
| VS3-XY385 | Mouse Anti-CD6 Recombinant Antibody (clone 1G6A4) | ELISA, WB, IHC, FC | Mouse IgG2b |
| VS3-XY386 | Mouse Anti-CD6 Recombinant Antibody (clone 2D12C6) | ELISA, WB, IHC, FC | Mouse IgG2b |
| VS3-XY387 | Mouse Anti-CD6 Recombinant Antibody (clone 8D5B4C11) | ELISA, WB, IHC, FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY63 | CytoStream™ Rat Anti-CD6 Recombinant Antibody (VS-0225-XY63) | FC | Rat IgG2a, lambda |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY90 | Mouse Anti-CD6 (clone IOR-T1) scFv-Fc Chimera | ELISA | Mouse IgG2a, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC197 | Recombinant Anti-CD6 Vesicular Antibody, EV Displayed (VS-0425-YC197) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1206 | Anti-CD6 Immunohistochemistry Kit | IHC |
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