Recombinant Mouse Anti-CEA Soluble TCR

Name: Recombinant Mouse Anti-CEA Soluble TCR
SKU: scTCR-025CQ-S(P)
Rating: 5 (1 reviews)

CAT#: scTCR-025CQ-S(P)

Recombinant Mouse single-chain TCR (scTCR) recognizes CEA peptide (IMIGVLVGV) in the context of HLA-A*0201. The scTCR is responsible for the specificity of T cells.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HaCaT

Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19758/1660_G5_2_selected.jpg

Subcellular Location Figure 2 IHC staining of human duodenum

Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in a subset of leukocytes.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11041/ihc_selected.jpg

Normal Tissue Figure 3 Colon

Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Gradient
Gradient: Ascending
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21/19_A_7_3.jpg

Normal Tissue Figure 4 Rectum

Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21/19_A_6_3.jpg

RNA Expression Figure 5 RNA cell line category: Cell line enriched (OE19)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105388-CEACAM5

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Specifications

Host Species
Mouse

Target
CEA

Species Reactivity
Human

Epitope
IMIGVLVGV

MHC
HLA-A*0201

Type
Single-Chain TCR

Related Disease
Colorectal cancer

Target

Alternative Names
CEA; CD66e; CEACAM5; carcinoembryonic antigen related cell adhesion molecule 5

Gene ID
1048

UniProt ID
P06731

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Datasheet

Datasheet - scTCR-025CQ-S(P).pdf

MSDS

MSDS - scTCR-025CQ-S(P).pdf

COA

Certificate of Analysis Lookup

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