Mouse Anti-CFTR Recombinant Antibody (clone CF3) (CAT#: NEUT-458CQ)
This antibody is a mouse monoclonal antibody that binds specifically to CFTR, and it can neutralize the bioactivity of CFTR.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_1_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_1_3_val_selected.jpg
Figure 2 Low expression in skeletal muscle.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1951/160344_B_3_6_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1951/160344_B_3_6_val_selected.jpg
Figure 3 Low expression in lymph node
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_9_8_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_9_8_val_selected.jpg
Figure 4 Pancreas
(Exocrine glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_1_3.jpg
(Exocrine glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21939/169902_A_1_3.jpg
Figure 5 RNA cell line category: Group enriched (CACO-2, MOLT-4, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000001626-CFTR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000001626-CFTR
Specifications
- Immunogen
- Synthetic Peptide: G (103) RIIASYDPDNKEER (117)
- Host Species
- Mouse
- Type
- Mouse IgM
- Specificity
- Human CFTR
- Species Reactivity
- Human, Mouse, Chicken, Rat
- Clone
- CF3
- Applications
- Block, FC, ICC, IF, IHC, IHC-P, IP, WB
- Conjugate
- Unconjugated
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CFTR; cystic fibrosis transmembrane conductance regulator; CF; MRP7; ABC35; ABCC7; CFTR/MRP; TNR-CFTR; dJ760C5.1
- Gene ID
- 1080
- UniProt ID
- P13569
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Single Domain Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1704z | Mouse Anti-CFTR Recombinant Antibody (clone 28C12) | WB, IF, IHC | Mouse IgG1 |
| MOB-0481CT | Recombinant Mouse anti-Human CFTR Monoclonal antibody (N4B8) | FC, IHC-Fr, IHC-P | |
| MRO-1772-CN | Rabbit Anti-CFTR Polyclonal Antibody (MRO-1772-CN) | WB, IF, IHC, FC | Rabbit IgG |
| PABS-0273 | Camelid Anti-CFTR Recombinant Antibody (PABS-0273) | Thermal shift assay (DSF), Isothermal titration microcalorimertry (ITC), Differential scanning calorimetry (DSC), FC, pull-down, ELISA, FuncS | Camelid VHH |
| PABS-0274 | Camelid Anti-CFTR Recombinant Antibody (clone G3a) | Thermal shift assay (DSF), Isothermal titration microcalorimertry (ITC), Differential scanning calorimetry (DSC), FC, Pull-down, ELISA, FuncS | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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