Anti-CFTR Recombinant Antibody Products

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Anti-CFTR Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs provides an extensive selection of anti-CFTR recombinant antibodies tailored to support researchers globally in their cancer research endeavors. Our expert research team is committed to delivering high-quality antibodies and offers comprehensive technical support. Furthermore, we supply a range of efficacy data to serve as valuable references for your meaningful projects.

CFTR: A Potential Cancer Treatment Target

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), a protein primarily implicated in cystic fibrosis, has emerged as a promising therapeutic target for cancer. Mutations in the CFTR gene trigger the multi-organ condition cystic fibrosis (CF), which is caused by decreased or malfunctioning CFTR protein. Recent studies have highlighted CFTR's critical role in tumorigenesis, metastasis, and chemoresistance. These findings underscore the potential benefits of targeting CFTR for the development of innovative anticancer therapies.

Alternative Names

Cystic fibrosis transmembrane conductance regulator; CF transmembrane conductance regulator; ABC35; ABCC7; CF; CFTR/MRP; MRP7; TNR-dJ760C5.1.

Background

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. [provided by RefSeq, Aug 2017].

Anti-CFTR rAb Products

Creative Biolabs offers a comprehensive range of high-quality anti-CFTR recombinant antibodies, meticulously designed to support groundbreaking cancer research worldwide. Our products precisely target the CFTR protein, a key player in cancer-related pathways, facilitating a deeper understanding of its role in tumorigenesis and progression. Available in various formats to meet your specific research needs, our anti-CFTR antibodies are essential tools for unraveling the complexities of cancer biology.

Table 1. Featured anti-CFTR recombinant antibody products at Creative Biolabs.

Creative Quality Control

Creative Biolabs is committed to offering researchers an extensive selection of premium anti-CFTR antibodies. Each antibody undergoes rigorous testing to ensure it meets exceptional quality standards and performs effectively across diverse applications. Our unwavering commitment to quality ensures that our products adhere to the industry's highest benchmarks, delivering reliable and consistent results to support your scientific investigations.

Customer Reviews

Excellent

Lu***y
Camelid Anti-CFTR Recombinant Antibody (clone G3a) (PABS-0274)

The anti-CFTR recombinant antibodies from Creative Biolabs have been instrumental in our flow cytometry experiments. The high specificity and sensitivity of these antibodies have allowed us to accurately quantify CFTR expression levels in various cell lines. The consistent results we've obtained have significantly enhanced the reliability of our data.

6/Jul/2021

Excellent

Ev***s
Mouse Anti-CFTR Recombinant Antibody (clone CF3) (NEUT-458CQ)

We've been using Creative Biolabs' anti-CFTR antibodies for blocking experiments and have been extremely impressed with their performance. The antibodies effectively block CFTR function, allowing us to study the downstream effects of CFTR inhibition in a controlled manner. The high purity and low non-specific binding of these antibodies have been crucial in ensuring the accuracy of our results.

25/May/2022

Excellent

Le***s
Mouse Anti-CFTR Recombinant Antibody (clone 28C12) (MOB-1704z)

The anti-CFTR recombinant antibodies provided by Creative Biolabs have proven to be essential for our immunohistochemistry research. Their exceptional staining patterns and high signal-to-noise ratio have allowed us to clearly visualize CFTR expression across various tissue types. Additionally, the consistent reproducibility of the staining results has greatly benefited our studies.

15/Oct/2023

rAb Production

Creative Biolabs employs a cutting-edge recombinant antibody platform that harnesses the latest genetic engineering techniques to produce top-quality anti-CFTR antibodies. This innovative method facilitates efficient and adaptable antibody production, guaranteeing a consistent supply of antibodies that cater to the varied needs of researchers across different fields.

Featured Anti-CFTR Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-CFTR recombinant antibody production.

Fig.2 Gram-scale anti-CFTR recombinant antibody production.

rAb Modalities

Creative Biolabs provides an extensive range of premium anti-CFTR recombinant antibodies, offered in multiple formats to accommodate your unique research requirements.

Fig.3 Full-length anti-CFTR recombinant antibody production and modalities.

CFTR-Targeted Drug Information

Table 2. Public drug targeting CFTR.

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Creative Biolabs leads the way in antibody research, merging a strong theoretical background with extensive practical experience to provide high-quality, cost-effective anti-CFTR antibodies. To learn more about our selection of anti-CFTR antibody products and explore how they can elevate your research efforts, don't hesitate to contact us.