Anti-Human CXCR2 Recombinant Antibody (54B12) (CAT#: TAB-004MZ-VHH)
This antibody specifically binding to chemokine receptor CXCR2 may be used for treatment of diseases involving aberrant functioning of CXCR2.
Specific Inquiry
Figure 1 GRO-O concentration response curves in the presence of increasing concentrations of sdAb
The response curves obtained when the ability of two sdAbs and a biparatopic sdAb of the invention to block [35S]GTPγS release from CHO CXCR2 membranes stimulated with agonist Gro-α at is measured at increasing concentrations of sdAb, the result for sdAb 54B12.
Figure 2 GRO-O concentration response curves in the presence of increasing concentrations of sdAb
The response curves obtained when the ability of two sdAbs and a biparatopic sdAb of the invention to block [35S]GTPγS release from CHO-CXCR2 membranes stimulated with agonist Gro-α at is measured at increasing concentrations of sdAb, the result for biparatopic sdAb 54B12/163E3.
Specifications
- Host Species
- Human
- Type
- Single domain antibody
- Specificity
- Human
- Clone
- 54B12
- Applications
- ELISA, IHC, FuncS, SPR
- Related Disease
- Chronic obstructive pulmonary disease (COPD)
Applications
- Application Notes
- The antibody was validated for ELISA, Immunohistochemistry, Functional Assay, Surface plasmon resonance. For details, refer to Published Data.
Target
- Alternative Names
- CXCR2; chemokine (C-X-C motif) receptor 2; CD182; IL8R2; IL8RA; IL8RB; CMKAR2; CDw128b; C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; IL-8R B; GRO/MGSA receptor; IL-8 receptor type 2; interleukin 8 receptor B; chemokine (CXC) receptor 2; interleukin 8 receptor, beta; interleukin 8 receptor type 2; interleukin-8 receptor type B; CXCR2 gene for IL8 receptor type B; high affinity interleukin-8 receptor B
- Gene ID
- 3579
- UniProt ID
- P25025
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-050 | Recombinant Anti-Human CXCR2 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-002MZ-VHH | Anti-Human CXCR2 Recombinant Antibody (2B2) | FC, Inhib | Single domain antibody |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-117MZ | Anti-Human CXCR2 Recombinant Antibody (HY29) | FC, FuncS, Inhib | Humanized antibody |
| TAB-118MZ | Anti-Human CXCR2 Recombinant Antibody (HY29GL) | FC, FuncS, Inhib | Humanized antibody |
| TAB-117MZ-S(P) | Anti-Human CXCR2 Recombinant Antibody scFv Fragment (HY29) | ELISA | Humanized antibody |
| TAB-118MZ-S(P) | Anti-Human CXCR2 Recombinant Antibody scFv Fragment (HY29GL) | ELISA | Humanized antibody |
| TAB-117MZ-F(E) | Anti-Human CXCR2 Recombinant Antibody Fab Fragment (HY29) | ELISA | Humanized antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-119MZ-F(E) | Anti-Human CXCR2 Recombinant Antibody Fab Fragment (CX2-Mab#1) | ELISA | Human antibody |
| TAB-120MZ-F(E) | Anti-Human CXCR2 Recombinant Antibody Fab Fragment (CX2-Mab#2) | ELISA | Human antibody |
| TAB-121MZ-F(E) | Anti-Human CXCR2 Recombinant Antibody Fab Fragment (CX2-Mab#3) | ELISA | Human antibody |
| TAB-122MZ-F(E) | Anti-Human CXCR2 Recombinant Antibody Fab Fragment (CX2-Mab#4) | ELISA | Human antibody |
| TAB-123MZ-F(E) | Anti-Human CXCR2 Recombinant Antibody Fab Fragment (CX2-Mab#5) | ELISA | Human antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2067MZ | Recombinant Mouse Anti-Human CXCR2 Antibody (clone 20) | ELISA, ELISA, FC, IHC-P, WB | Mouse antibody |
| HPAB-0306-YC | Human Anti-CXCR2 Recombinant Antibody (clone HY29) | ELISA, FC, FuncS | Humanized IgG1 |
| HPAB-0417-CN | Human Anti-CXCR2 Recombinant Antibody (clone ZY05KA-G08) | ELISA | Chimeric (mouse/human) IgG |
| VS-0723-WK66 | Human Anti-CXCR2 Recombinant Antibody (VS-0723-WK66) | FC | Chimeric (rabbit/human) IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-671CQ | Mouse Anti-CXCR2 Recombinant Antibody (clone CBL044) | FC, IHC, Neut | Mouse IgG2 |
| NEUT-672CQ | Mouse Anti-CXCR2 Recombinant Antibody (clone MM0222-7J40) | IHC-Fr, Neut, FC | Mouse IgG2a |
| NEUT-673CQ | Mouse Anti-CXCR2 Recombinant Antibody (clone CBL790) | FC, IHC, CyTOF®, Neut | Mouse IgG2a |
| NEUT-674CQ | Mouse Anti-CXCR2 Recombinant Antibody (clone CBL791) | Neut, FC | Mouse IgG2a |
| NEUT-675CQ | Rat Anti-Cxcr2 Recombinant Antibody (clone CBL867) | FC, Neut | Rat IgG2 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0306-YC-S(P) | Human Anti-CXCR2 Recombinant Antibody (clone HY29); scFv Fragment | ELISA, FC, FuncS | Humanized scFv |
| HPAB-0417-CN-S(P) | Mouse Anti-CXCR2 Recombinant Antibody (clone ZY05KA-G08); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0306-YC-F(E) | Human Anti-CXCR2 Recombinant Antibody (clone HY29); Fab Fragment | ELISA, FC, FuncS | Humanized Fab |
| HPAB-0417-CN-F(E) | Human Anti-CXCR2 Recombinant Antibody (clone ZY05KA-G08); Fab Fragment | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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