Anti-Human CXCR2 Therapeutic Antibody (54B12) (CAT#: TAB-004MZ-VHH)

This antibody specifically binding to chemokine receptor CXCR2 may be used for treatment of diseases involving aberrant functioning of CXCR2.

  • Published Data
  • Datasheet
  • MSDS
  • COA

Figure 1 GRO-O concentration response curves in the presence of increasing concentrations of nanobody

The response curves obtained when the ability of two Nanobodies and a biparatopic Nanobody of the invention to block [35S]GTPγS release from CHO CXCR2 membranes stimulated with agonist Gro-α at is measured at increasing concentrations of Nanobody, the result for Nanobody 54B12.

Figure 2 GRO-O concentration response curves in the presence of increasing concentrations of nanobody

The response curves obtained when the ability of two Nanobodies and a biparatopic Nanobody of the invention to block [35S]GTPγS release from CHO-CXCR2 membranes stimulated with agonist Gro-α at is measured at increasing concentrations of Nanobody, the result for biparatopic Nanobody 54B12/163E3.


Specifications

  • Host Species
  • Human
  • Type
  • Single domain antibody
  • Specificity
  • Human
  • Clone
  • 54B12
  • Applications
  • ELISA, IHC, FuncS, SPR
  • Related Disease
  • Chronic obstructive pulmonary disease (COPD)

Applications

  • Application Notes
  • The antibody was validated for ELISA, Immunohistochemistry, Functional Assay, Surface plasmon resonance. For details, refer to Published Data.

Target

  • Alternative Names
  • CXCR2; chemokine (C-X-C motif) receptor 2; CD182; IL8R2; IL8RA; IL8RB; CMKAR2; CDw128b; C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; IL-8R B; GRO/MGSA receptor; IL-8 receptor type 2; interleukin 8 receptor B; chemokine (CXC) receptor 2; interleukin 8 receptor, beta; interleukin 8 receptor type 2; interleukin-8 receptor type B; CXCR2 gene for IL8 receptor type B; high affinity interleukin-8 receptor B

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

See other products for "CXCR2"

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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