Human Anti-CXCR4 Recombinant Antibody (clone hz515H7VH1D76NVL2); Fab Fragment (CAT#: HPAB-0044-YC-F(E))
Chemokine receptor 4 (also known as fusin, CD 184, LESTR or HUMSTR) exists as two isoforms comprising 352 or 360 amino acids. Targeting cancer metastases by interfering with CXCR4 receptor was demonstrated in vivo using a monoclonal antibody directed against CXCR4 receptor.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (Daudi, JURKAT, Karpas-707, MOLT-4, REH, U-266/70, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121966-CXCR4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121966-CXCR4
Figure 1 RNA cell line category: Cell line enhanced (Daudi, JURKAT, Karpas-707, MOLT-4, REH, U-266/70, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121966-CXCR4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121966-CXCR4
Specifications
- Immunogen
- Recombinant NIH3T3-CXCR4cells and/or peptides corresponding to CXCR4 extracellular N-term and loops
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human CXCR4
- Species Reactivity
- Human
- Clone
- hz515H7VH1D76NVL2
- Applications
- Block, Cyt, FC
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Chemokine (C-X-C Motif) Receptor 4; Leukocyte-Derived Seven Transmembrane Domain Receptor; Lipopolysaccharide-Associated Protein 3; Stromal Cell-Derived Factor 1 Receptor; LPS-Associated Protein 3; SDF-1 Receptor; CD184 Antigen; Fusin; LAP-3; LESTR; NPYRL; FB22; HM89; LCR1; Seven-Transmembrane-Segment Receptor, Spleen; Chemokine (C-X-C Motif), Receptor 4 (Fusin); Seven Transmembrane Helix Receptor; Neuropeptide Y Receptor Y3; Neuropeptide Y3 Receptor; D2S201E; HSY3RR; NPYY3R; CXC-R4; CXCR-4; CD184; NPY3R; WHIMS; NPYR; LAP3; WHIM
- Gene ID
- 7852
- UniProt ID
- P61073
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1224z | Mouse Anti-CXCR4 Recombinant Antibody (clone 12B3) | FC, ICC, IHC, FuncS | Mouse IgG2a |
| HPAB-1685-FY | Human Anti-CXCR4 Recombinant Antibody (clone Hz515H7-VH1-D76N-VL2) | ELISA, FC | Humanized IgG1 |
| HPAB-1686-FY | Human Anti-CXCR4 Recombinant Antibody (HPAB-1686-FY) | FC | Human IgG1 |
| HPAB-1687-FY | Human Anti-CXCR4 Recombinant Antibody (HPAB-1687-FY) | FC | Human IgG1 |
| HPAB-1688-FY | Human Anti-CXCR4 Recombinant Antibody (HPAB-1688-FY) | FC | Human IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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