CytoStream™ Rabbit Anti-CXCR4 Polyclonal Antibody (VS13-YC278) (CAT#: VS13-YC278)

• Immunogen
• Recombinant human CXCR4 (aa 201-294) conjugated with KLH.

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse and Rat CXCR4

• Species Reactivity
• Human, Mouse, Rat, Rabbit (Predicted), Cow (Predicted)

• Applications
• WB, ELISA, IHC-P, IHC-Fr, FC, IF

• Conjugate
• NONE

• Related Disease
• Whim Syndrome; Macroglobulinemia

• Clonality
• Polyclonal

• Purification
• Affinity Chromatography purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• 0.01× TBS (pH 7.4) containing 50% Glycerol and 1% BSA.

• Preservative
• 0.03% Proclin 300

• Storage
• Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Shipping with ice pack.

• Application Notes
• Western blot (WB): 1/500-1/2000
  ELISA: 1/5000-1/10000
  Immunohistochemistry-paraffin (IHC-P): 1/100-1/500
  Immunohistochemistry-frozen (IHC-Fr): 1/100-1/500
  Flow cytometry (FC): 1 μg per 1x 10⁶ cells
  Immunofluorescence (IF): 1/100-1/500

• Alternative Names
• C-X-C Motif Chemokine Receptor 4; Leukocyte-Derived Seven Transmembrane Domain Receptor; Lipopolysaccharide-Associated Protein 3; Stromal Cell-Derived Factor 1 Receptor; Chemokine (C-X-C Motif) Receptor 4; LPS-Associated Protein 3; SDF-1 Receptor; CD184 Antigen; Fusin; LAP-3; LESTR; NPYRL; FB22; HM89; LCR1; Seven-Transmembrane-Segment Receptor, Spleen; Chemokine (C-X-C Motif), Receptor 4 (Fusin);

• Gene ID
• 7852

• UniProt ID
• P61073

• Long Name
• C-X-C Motif Chemokine Receptor 4

• Cellular Localization
• Cell membrane; Cell junction

• Protein Refseq
• XP_047301758.1; NP_001008540.1

• Function
• Involved in the AKT signaling cascade. Plays a role in regulation of cell migration, e.g.during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels.

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-061CQ
• Sheep Anti-Rabbit IgG (H&L) Antibody

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

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