CytoStream™ Rabbit Anti-CXCR4 Polyclonal Antibody (VS13-YC278)

CAT#: VS13-YC278

The CytoStream™ Rabbit Anti-CXCR4 Polyclonal Antibody is specific for human, mouse and rat CXCR4. CXCR4 participates in chemokine receptor interactions, associated with HIV infection facilitation and uterine implantation processes through chemotactic activity. The anti-CXCR4 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1 μg per 1x 10⁶ cells).

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (Daudi, JURKAT, Karpas-707, MOLT-4, REH, U-266/70, U-698)

Specifications

  • Immunogen
  • Recombinant human CXCR4 (aa 201-294) conjugated with KLH.
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat CXCR4
  • Species Reactivity
  • Human, Mouse, Rat, Rabbit (Predicted), Cow (Predicted)
  • Applications
  • WB, ELISA, IHC-P, IHC-Fr, FC, IF
  • Conjugate
  • NONE
  • Related Disease
  • Whim Syndrome; Macroglobulinemia

Product Property

  • Clonality
  • Polyclonal
  • Purification
  • Affinity Chromatography purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 0.01× TBS (pH 7.4) containing 50% Glycerol and 1% BSA.
  • Preservative
  • 0.03% Proclin 300
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Shipping with ice pack.

Applications

  • Application Notes
  • Western blot (WB): 1/500-1/2000
    ELISA: 1/5000-1/10000
    Immunohistochemistry-paraffin (IHC-P): 1/100-1/500
    Immunohistochemistry-frozen (IHC-Fr): 1/100-1/500
    Flow cytometry (FC): 1 μg per 1x 10⁶ cells
    Immunofluorescence (IF): 1/100-1/500

Target

  • Alternative Names
  • C-X-C Motif Chemokine Receptor 4; Leukocyte-Derived Seven Transmembrane Domain Receptor; Lipopolysaccharide-Associated Protein 3; Stromal Cell-Derived Factor 1 Receptor; Chemokine (C-X-C Motif) Receptor 4; LPS-Associated Protein 3; SDF-1 Receptor; CD184 Antigen; Fusin; LAP-3; LESTR; NPYRL; FB22; HM89; LCR1; Seven-Transmembrane-Segment Receptor, Spleen; Chemokine (C-X-C Motif), Receptor 4 (Fusin);
  • Long Name
  • C-X-C Motif Chemokine Receptor 4
  • Cellular Localization
  • Cell membrane; Cell junction
  • Function
  • Involved in the AKT signaling cascade. Plays a role in regulation of cell migration, e.g.during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Secondary Antibody

Isotype Control

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