Afuco™ Anti-Human FGFR4 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-273CL)
Anti-FGFR4 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The FGFR4 antibodies are suitable for diagnosing, preventing and/or treatment of diseases associated with FGFR4 expression. FGFR4 has been found to be expressed and/or influencing prognostic outcome in several types of cancer such as melanoma, breast, prostate, thyroid and pancreatic cancers.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human smooth muscle
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27273/ihc_selected.jpg
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27273/ihc_selected.jpg
Figure 2 IHC staining of human gall bladder
(Immunohistochemical staining of human gall bladder shows strong cytoplasmic and membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/ihc_selected.jpg
(Immunohistochemical staining of human gall bladder shows strong cytoplasmic and membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/ihc_selected.jpg
Figure 3 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5196/ihc_selected.jpg
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5196/ihc_selected.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_3.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_4.jpg
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_7_5.jpg
Figure 7 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_4_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_4_6.jpg
Figure 8 RNA cell line category: Group enriched (CACO-2, Hep G2, RH-30)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160867-FGFR4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160867-FGFR4
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Liver Cancer
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C
Target
- Alternative Names
- FGFR4; fibroblast growth factor receptor 4; TKF; JTK2; CD334; tyrosylprotein kinase; protein-tyrosine kinase; hydroxyaryl-protein kinase; tyrosine kinase related to fibroblast growth factor receptor
- Gene ID
- 2264
- UniProt ID
- B4DVP5
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-066WM | Anti-Human FGFR4 Recombinant Antibody (XPA.48.056) | ELISA, FC | Human Antibody |
| TAB-066WM-S(P) | Anti-Human FGFR4 Recombinant Antibody scFv Fragment (XPA.48.056) | ELISA, FC | Human Antibody |
| TAB-066WM-F(E) | Anti-Human FGFR4 Recombinant Antibody Fab Fragment (XPA.48.056) | ELISA, FC | Human Antibody |
| TAB-384CQ | Human Anti-FGFR4 Recombinant Antibody (TAB-384CQ) | ELISA | Human IgG |
| TAB-384CQ-F(E) | Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (TAB-384CQ-F(E)) | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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