Anti-HIV-1 antibody is a Mouse antibody of IgG class that binds to an HIV-1. This antibody binds to a portion of the surface of the p51 palm subdomain and has no contacts with either the p66 subunit or the dsDNA. The segment of p51 containing the Fab28 epitope corresponds to the b12-b13-b14 sheet of p66.
Figure 1 Ribbon (Carson, 1987) diagram showing the overall structure of the HIV-1 RT/dsDNA/Fab28 complex.
The subdomains of the p66 and p51 subunits of HIV-1 RT are colored as follows: ®ngers, blue; palm, red; thumb, green; connection, yellow; and RNase H, orange. The bound dsDNA is shown with the template strand as a dark gray ribbon and the primer strand as a light gray ribbon; base-pairs are represented by bars. The monoclonal antibody fragment Fab28 is shown with the light chain in light gray and the heavy chain in dark gray.
Ding, J., Das, K., Hsiou, Y., Sarafianos, S. G., Clark Jr, A. D., Jacobo-Molina, A., ... & Arnold, E. (1998). Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 Å resolution. Journal of molecular biology, 284(4), 1095-1111.
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CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1889-sdAb | Recombinant Anti-HIV-1 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
PNBL-038 | Recombinant Anti-HIV-1 C186 gp120 VHH Single Domain Antibody (A12) | WB, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-068 | Anti-HIV-1 Recombinant Antibody (Suvizumab) | WB, ELISA, IP, FC, FuncS, Neut, IF | IgG1 - kappa |
PABX-094-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment (Fab4025) | WB, ELISA, FuncS | scFv |
PABX-099-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment | FC, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G037E | Anti-HIV-1 immunotoxin 3B3 (scFv)-PE | Cytotoxicity assay, Function study | |
AGTO-G037D | Anti-HIV-1 immunotoxin 3B3 (scFv)-DT | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-140 | Human Anti-HIV-1 Recombinant Antibody (clone VRC26.25); scFv Fragment | WB, ELISA, Neut, FuncS | Human scFv |
FAMAB-0176CQ-S(P) | Mouse Anti-HIV-1 Recombinant Antibody (clone KEL10); scFv Fragment | ELISA, Neut | Mouse scFv |
HPAB-AP363-YC-S(P) | Human Anti-HIV-1 Recombinant Antibody (clone A2); scFv Fragment | ELISA, Neut | Human scFv |
HPAB-1988-FY-S(P) | Human Anti-HIV-1 Recombinant Antibody (clone 2G9); scFv Fragment | FC, ELISA | Human scFv |
HPAB-1989-FY-S(P) | Human Anti-HIV-1 Recombinant Antibody (clone 9F11); scFv Fragment | FC, ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-140 | Human Anti-HIV-1 Recombinant Antibody (clone VRC26.25); Fab Fragment | WB, ELISA, Neut, FuncS | Human Fab |
FAMAB-0176CQ-F(E) | Mouse Anti-HIV-1 Recombinant Antibody (clone KEL10); Fab Fragment | ELISA, Neut | Mouse Fab |
HPAB-AP363-YC-F(E) | Human Anti-HIV-1 Recombinant Antibody (clone A2); Fab Fragment | ELISA, Neut | Human Fab |
HPAB-1988-FY-F(E) | Human Anti-HIV-1 Recombinant Antibody (clone 2G9); Fab Fragment | FC, ELISA | Human Fab |
HPAB-1989-FY-F(E) | Human Anti-HIV-1 Recombinant Antibody (clone 9F11); Fab Fragment | FC, ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-001 | Recombinant Human Anti-HIV-1 Antibody (1281) | WB, FuncS, Neut, SPR | IgG |
PABX-008-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment | WB, IHC, IF, FuncS | scFv |
PABX-095-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (Fab59.1) | Neut, ELISA, FuncS | scFv |
PABX-001-F (E) | Recombinant Human Anti-HIV-1 Antibody Fab Fragment (1281) | WB, FuncS | Fab |
PABX-087-F(E) | Human Anti-HIV-1 Recombinant Antibody; Fab Fragment (PABX-087-F(E)) | WB, ELISA, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-008 | Recombinant Mouse Anti-HIV-1 Antibody | WB, IHC, IF, FuncS | IgG |
PABX-084-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (83.1) | WB, ELISA, FuncS | scFv |
PABX-087-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment (2G12) | WB, ELISA, FuncS | scFv |
PABX-088-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment (447-52D) | WB, ELISA, IF, FuncS | scFv |
PABX-089-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (A10F9) | Neut, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-093-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (Fab28) | WB, ELISA, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC1376 | PE-A*02:01/HIV-1 (SLFNTVATL) MHC Tetramer | FCM | |
MHC-LC1377 | APC-A*02:01/HIV-1 (SLFNTVATL) MHC Tetramer | FCM | |
MHC-LC1378 | BV421-A*02:01/HIV-1 (SLFNTVATL) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4221 | Rabbit Anti-HIV-1 Recombinant Antibody (clone SI300DS) | ELISA, ICC, IF, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0176CQ | Mouse Anti-HIV-1 Recombinant Antibody (clone KEL10) | ELISA, Neut | Mouse IgG |
HPAB-1988-FY | Human Anti-HIV-1 Recombinant Antibody (clone 2G9) | FC, ELISA, Neut | Human IgM |
HPAB-1989-FY | Human Anti-HIV-1 Recombinant Antibody (clone 9F11) | FC, CMCD | Human IgM |
VS-0423-XY8 | Mouse Anti-HIV-1 Recombinant Antibody (clone CP503) | ELISA | Mouse IgG |
VS-0423-XY9 | Mouse Anti-HIV-1 Recombinant Antibody (clone CP506) | ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-068 | Afuco™ Anti-HIV-1 ADCC Recombinant Antibody (Suvizumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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