Recombinant Mouse Anti-HIV-1 Antibody (Fab28) (CAT#: PABX-093)

Figure 1 Ribbon (Carson, 1987) diagram showing the overall structure of the HIV-1 RT/dsDNA/Fab28 complex.

The subdomains of the p66 and p51 subunits of HIV-1 RT are colored as follows: ®ngers, blue; palm, red; thumb, green; connection, yellow; and RNase H, orange. The bound dsDNA is shown with the template strand as a dark gray ribbon and the primer strand as a light gray ribbon; base-pairs are represented by bars. The monoclonal antibody fragment Fab28 is shown with the light chain in light gray and the heavy chain in dark gray.

Ding, J., Das, K., Hsiou, Y., Sarafianos, S. G., Clark Jr, A. D., Jacobo-Molina, A., ... & Arnold, E. (1998). Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 Å resolution. Journal of molecular biology, 284(4), 1095-1111.