Anti-HIV-1 Recombinant Antibody (TAB-068)
CAT#: TAB-068
Recombinant monoclonal antibody to HIV-1. It is a 'first in class' humanized IgG1 monoclonal antibody. It selectively targets CD6, a pan T cell marker involved in co-stimulation, adhesion and maturation of T cells. It, by binding to CD6, down regulates T cell activation, causes reduction in synthesis of pro-inflammatory cytokines and possibly plays an important role by reducing T cell infiltration at sites of inflammation. A double blind, placebo controlled, phase III treat -Plaq study of it successfully met the pre-specified primary end-point of significant improvement in PASI-75 (Psoriasis Area and Severity Index) score after 12 weeks of treatment in patients with moderate to severe psoriasis compared to placebo. Biocon has received marketing authorization for the drug from the Drugs Controller General of India (DCGI).
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- undefined
- Derivation
- Humanized
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native HIV-1 antigen.
- Species Reactivity
- HIV-1
- Applications
- Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.
- Related Disease
- HIV-1 infection, AIDS
Product Property
- Purity
- >95.0% as determined by analysis by RP-HPLC.
- Storage
- Store at -20°C. Avoid multiple freeze/thaw cycles.
Target
- Alternative Names
- Suvizumab;1116433-11-4;Alzumab;Suvizumab;HIV 1;HTLV3;Human Immunodeficiency Virus 1
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G037E | Anti-HIV-1 immunotoxin 3B3 (scFv)-PE | Cytotoxicity assay, Function study | |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-140 | Human Anti-HIV-1 Recombinant Antibody (clone VRC26.25); Fab Fragment | WB, ELISA, Neut, FuncS | Human Fab |
| FAMAB-0176CQ-F(E) | Mouse Anti-HIV-1 Recombinant Antibody (clone KEL10); Fab Fragment | ELISA, Neut | Mouse Fab |
| HPAB-0158-YJ-F(E) | Human Anti-HIV-1 Recombinant Antibody; Fab Fragment (HPAB-0158-YJ-F(E)) | ELISA, Neut, Inhib | Human Fab |
| HPAB-AP363-YC-F(E) | Human Anti-HIV-1 Recombinant Antibody (clone A2); Fab Fragment | ELISA, Neut | Human Fab |
| HPAB-1988-FY-F(E) | Human Anti-HIV-1 Recombinant Antibody (clone 2G9); Fab Fragment | FC, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-770CQ | Mouse Anti-HIV-1 Recombinant Antibody (clone 10 (03-002)) | EIA, WB, IHC, IP | Mouse IgG1 |
| MRO-771CQ | Mouse Anti-HIV-1 Recombinant Antibody (MRO-771CQ) | ELISA, WB | Mouse IgG1 |
| FAMAB-0176CQ | Mouse Anti-HIV-1 Recombinant Antibody (clone KEL10) | ELISA, Neut | Mouse IgG |
| HPAB-0158-YJ | Human Anti-HIV-1 Recombinant Antibody (HPAB-0158-YJ) | ELISA, Neut, Inhib | Chimeric (mouse/human) IgA1, κ |
| HPAB-AP363-YC | Human Anti-HIV-1 Recombinant Antibody (clone A2) | FuncS, FC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-001 | Recombinant Human Anti-HIV-1 Antibody (1281) | WB, FuncS, Neut, SPR | IgG |
| PABX-008-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment | WB, IHC, IF, FuncS | scFv |
| PABX-095-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (Fab59.1) | Neut, ELISA, FuncS | scFv |
| PABX-001-F (E) | Recombinant Human Anti-HIV-1 Antibody Fab Fragment (1281) | WB, FuncS | Fab |
| PABX-087-F(E) | Human Anti-HIV-1 Recombinant Antibody; Fab Fragment (PABX-087-F(E)) | WB, ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-008 | Recombinant Mouse Anti-HIV-1 Antibody | WB, IHC, IF, FuncS | IgG |
| PABX-084-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (83.1) | WB, ELISA, FuncS | scFv |
| PABX-087-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment (2G12) | WB, ELISA, FuncS | scFv |
| PABX-088-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment (447-52D) | WB, ELISA, IF, FuncS | scFv |
| PABX-089-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (A10F9) | Neut, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-093-S (P) | Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (Fab28) | WB, ELISA, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-094-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment (Fab4025) | WB, ELISA, FuncS | scFv |
| PABX-099-S (P) | Recombinant Human Anti-HIV-1 Antibody scFv Fragment | FC, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1376 | PE-A*02:01/HIV-1 (SLFNTVATL) MHC Tetramer | FCM | |
| MHC-LC1377 | APC-A*02:01/HIV-1 (SLFNTVATL) MHC Tetramer | FCM | |
| MHC-LC1378 | BV421-A*02:01/HIV-1 (SLFNTVATL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4221 | Rabbit Anti-HIV-1 Recombinant Antibody (clone SI300DS) | ELISA, ICC, IF, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0176CQ-S(P) | Mouse Anti-HIV-1 Recombinant Antibody (clone KEL10); scFv Fragment | ELISA, Neut | Mouse scFv |
| HPAB-0158-YJ-S(P) | Mouse Anti-HIV-1 Recombinant Antibody; scFv Fragment (HPAB-0158-YJ-S(P)) | ELISA, Neut, Inhib | Mouse scFv |
| HPAB-AP363-YC-S(P) | Human Anti-HIV-1 Recombinant Antibody (clone A2); scFv Fragment | ELISA, Neut | Human scFv |
| HPAB-1988-FY-S(P) | Human Anti-HIV-1 Recombinant Antibody (clone 2G9); scFv Fragment | FC, ELISA | Human scFv |
| HPAB-1989-FY-S(P) | Human Anti-HIV-1 Recombinant Antibody (clone 9F11); scFv Fragment | FC, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-068 | Afuco™ Anti-HIV-1 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-068) | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1988-FY | Human Anti-HIV-1 Recombinant Antibody (clone 2G9) | FC, ELISA, Neut | Human IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY67 | Human Anti-HIV-1 (clone 3D6) scFv-Fc Chimera | Neut | Human IgG1, scFv-Fc |
| VS-0125-FY68 | Human Anti-HIV-1 (clone 2F5) scFv-Fc Chimera | Neut | Human IgG1, scFv-Fc |
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