Human Anti-HIV-1 (clone 2F5) scFv-Fc Chimera (CAT#: VS-0125-FY68)

The anti-HIV-1 single-chain antibody (scFv) Fc fusion protein 2F5 is a molecule of significant biomedical importance. This antibody targets core antigens of the HIV-1 virus and is capable of effectively neutralizing the virus. The design of the 2F5 antibody combines the flexibility of single-chain antibodies with the stability of the Fc portion, enhancing its ability to recognize and eliminate the virus. Research has shown that 2F5 can block the binding of HIV-1 to receptors on the surface of host cells, thereby preventing viral infection. This antibody holds great promise for applications in HIV vaccine development and therapeutic research.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
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  • Fc Engineering:
  • Modalities:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Species Reactivity
  • Human immunodeficiency virus (HIV)
  • Clone
  • 2F5
  • Applications
  • Neutralization
  • Related Disease
  • HIV infection

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Stabilizer
  • No Stabilizers
  • Sterility
  • 0.2 μM filtered
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • The potential function of scFv-Fc antibodies lies in their ability to target specific antigens and neutralize HIV-1, effectively preventing the virus from entering host cells. The scFv segment enables precise binding to the virus, while the Fc region has the potential to activate immune responses, enhancing the activity of effector cells such as macrophages and natural killer cells.

Target

  • Alternative Names
  • HIV-1 Env; Human immunodeficiency virus 1 Envelope glycoprotein; HIV-1; Human immunodeficiency virus 1; Envelope glycoprotein; Env

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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CAT Product Name Application Type
NAB-1889-sdAb Recombinant Anti-HIV-1 VHH Single Domain Antibody WB, ICC, ChiP, FA, ELISA Llama VHH
PNBL-038 Recombinant Anti-HIV-1 C186 gp120 VHH Single Domain Antibody (PNBL-038) WB, FuncS Llama VHH

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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