Human Anti-HIV-1 (clone 2F5) scFv-Fc Chimera
CAT#: VS-0125-FY68
The anti-HIV-1 single-chain antibody (scFv) Fc fusion protein 2F5 is a molecule of significant biomedical importance. This antibody targets core antigens of the HIV-1 virus and is capable of effectively neutralizing the virus. The design of the 2F5 antibody combines the flexibility of single-chain antibodies with the stability of the Fc portion, enhancing its ability to recognize and eliminate the virus. Research has shown that 2F5 can block the binding of HIV-1 to receptors on the surface of host cells, thereby preventing viral infection. This antibody holds great promise for applications in HIV vaccine development and therapeutic research.
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- Human immunodeficiency virus (HIV)
- Clone
- 2F5
- Applications
- Neutralization
- Related Disease
- HIV infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The potential function of scFv-Fc antibodies lies in their ability to target specific antigens and neutralize HIV-1, effectively preventing the virus from entering host cells. The scFv segment enables precise binding to the virus, while the Fc region has the potential to activate immune responses, enhancing the activity of effector cells such as macrophages and natural killer cells.
Target
- Alternative Names
- HIV-1 Env; Human immunodeficiency virus 1 Envelope glycoprotein; HIV-1; Human immunodeficiency virus 1; Envelope glycoprotein; Env
- UniProt ID
- P04578
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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