Rabbit Anti-HTT Recombinant Antibody (clone DS1714AB)
CAT#: MOR-1714
Recombinant Rabbit anti-HTT monoclonal antibody for WB, IHC-P, ICC, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/55354_B_9_5_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/299_A6_2_red_green.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/298_A6_1_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Neuronal cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_B_8_5.jpg
Normal Tissue
Figure 6 Colon
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_7_3.jpg
Normal Tissue
Figure 7 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_9_5.jpg
Normal Tissue
Figure 8 Testis
Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_4_6.jpg
Normal Tissue
Figure 9 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_8_8.jpg
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Specifications
- Immunogen
- Synthetic peptide, corresponding to residues in the N terminus of Human Huntingtin.
- Host Species
- Rabbit
- Derivation
- Phage display library
- Type
- Rabbit IgG
- Specificity
- Human HTT
- Species Reactivity
- Human
- Clone
- DS1714AB
- Applications
- WB, IHC-P, ICC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1905-VHH | Recombinant Anti-human HTT VHH Single Domain Antibody | IHC, ICC, FC, FA, FUNC | Llama VHH |
| PABJ-0201 | Human Anti-HTT Recombinant Antibody (PABJ-0201) | ELISA, FuncS | Human VL |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-521 | Recombinant Anti-human HTT Antibody | WB, Neut, FuncS | IgG |
| MHH-521 | Recombinant Human Anti-human HTT Antibody | WB, Neut, FuncS | IgG |
| MOB-0905CT | Recombinant Mouse anti-Human HTT Monoclonal antibody (3502D2b) | Dot, WB | |
| HPAB-0123-YC | Mouse Anti-HTT Recombinant Antibody (HPAB-0123-YC) | IHC, WB, Inhib | Mouse IgG2a |
| ZG-0756J | Rabbit Anti-HTT Recombinant Antibody (clone 6F2) | ELISA, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-521-F(E) | Recombinant Anti-human HTT Antibody Fab Fragment | IP, IF, FuncS | Fab |
| MHH-521-F(E) | Recombinant Human Anti-human HTT Antibody Fab Fragment | Neut, WB, FuncS | Fab |
| HPAB-0121-YC-F(E) | Mouse Anti-HTT Recombinant Antibody (clone MW1); Fab Fragment | ELISA, FC, WB, IHC | Mouse Fab |
| HPAB-0122-YC-F(E) | Mouse Anti-HTT Recombinant Antibody; Fab Fragment (HPAB-0122-YC-F(E)) | ELISA, FC, WB, IHC | Mouse Fab |
| HPAB-0123-YC-F(E) | Mouse Anti-HTT Recombinant Antibody; Fab Fragment (HPAB-0123-YC-F(E)) | ELISA, FC, WB, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-521-S(P) | Recombinant Anti-human HTT Antibody scFv Fragment | FC, Neut, Funcs | scFv |
| HPAB-0121-YC-S(P) | Mouse Anti-HTT Recombinant Antibody (clone MW1); scFv Fragment | ELISA, FC, WB, IHC | Mouse scFv |
| HPAB-0122-YC-S(P) | Mouse Anti-HTT Recombinant Antibody; scFv Fragment (HPAB-0122-YC-S(P)) | ELISA, FC, WB, IHC | Mouse scFv |
| HPAB-0123-YC-S(P) | Mouse Anti-HTT Recombinant Antibody; scFv Fragment (HPAB-0123-YC-S(P)) | ELISA, FC, WB, IHC | Mouse scFv |
| HPAB-0125-YC-S(P) | Human Anti-HTT Recombinant Antibody; scFv Fragment (HPAB-0125-YC-S(P)) | ELISA, IHC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B023(A) | Recombinant Anti-human HTT Intrabody [(D-Arg)9] | ELISA, WB, ICC, FuncS | scFv-(D-Arg)9 |
| IAB-B023(G) | Recombinant Anti-human HTT Intrabody [+36 GFP] | IF, FC, WB, FuncS | scFv-(+36GFP) |
| IAB-B023(T) | Recombinant Anti-human HTT Intrabody [Tat] | WB, CO-IP, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-114CT | Human Anti-HTT Recombinant Antibody (TAB-114CT) | ELISA, WB | Human IgG1, κ |
| TAB-114CT-S(P) | Human Anti-HTT Recombinant Antibody; scFv Fragment (TAB-114CT-S(P)) | ELISA, WB | Human scFv |
| TAB-114CT-F(E) | Human Anti-HTT Recombinant Antibody; Fab Fragment (TAB-114CT-F(E)) | ELISA, WB | Human Fab |
| PABX-109 | Recombinant Human Anti-Huntingtin (Htt) Antibody | WB, Neut, FuncS | IgG |
| PABX-109-F (E) | Recombinant Human Anti-Huntingtin(Htt) Antibody Fab Fragment | WB, Neut, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-115CT-S(P) | Mouse Anti-HTT Recombinant Antibody; scFv Fragment (TAB-115CT-S(P)) | ELISA, WB | Mouse scFv |
| TAB-116CT-S(P) | Mouse Anti-HTT Recombinant Antibody; scFv Fragment (TAB-116CT-S(P)) | ELISA, WB | Mouse scFv |
| TAB-117CT-S(P) | Mouse Anti-HTT Recombinant Antibody; scFv Fragment (TAB-117CT-S(P)) | ELISA, WB | Mouse scFv |
| TAB-115CT-F(E) | Mouse Anti-HTT Recombinant Antibody; Fab Fragment (TAB-115CT-F(E)) | ELISA, WB | Mouse Fab |
| TAB-116CT-F(E) | Mouse Anti-HTT Recombinant Antibody; Fab Fragment (TAB-116CT-F(E)) | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0122-YC | Mouse Anti-HTT Recombinant Antibody (HPAB-0122-YC) | FuncS, WB, Inhib, IHC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-039CN | Human Anti-HTT Recombinant Antibody (NS-039CN) | ELISA, DB, IHC, FuncS | Human IgG |
| NS-039CN-F(E) | Human Anti-HTT Recombinant Antibody; Fab Fragment (NS-039CN-F(E)) | ELISA | Human Fab |
| NS-039CN-S(P) | Human Anti-HTT Recombinant Antibody; scFv Fragment (NS-039CN-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0066-FY | Rabbit Anti-HTT Recombinant Antibody (clone AFY0037) | FC, ICC, IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1080 | Anti-HTT Immunohistochemistry Kit | IHC | |
| VS-0525-XY3360 | Anti-Mouse HTT Immunohistochemistry Kit | IHC | |
| VS-0525-XY3359 | Anti-Human HTT Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC384 | Recombinant Anti-HTT Vesicular Antibody, EV Displayed (VS-0425-YC384) | ELISA, FC, Neut, Cell-uptake |
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