Recombinant Anti-human HTT VHH Single Domain Antibody
CAT#: NAB-1905-VHH
Anti-human HTT VHH Single Domain Antibody is a recombinant protein produced in E. coli.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/55354_B_9_5_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/299_A6_2_red_green.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/298_A6_1_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Neuronal cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_B_8_5.jpg
Normal Tissue
Figure 6 Colon
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_7_3.jpg
Normal Tissue
Figure 7 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_9_5.jpg
Normal Tissue
Figure 8 Testis
Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_4_6.jpg
Normal Tissue
Figure 9 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_8_8.jpg
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Specifications
- Immunogen
- human huntingtin
- Host Species
- Llama
- Type
- Llama VHH
- Species Reactivity
- Human
- Molecule Class
- VHH Single Domain Antibody
- Applications
- This product is suitable for use in IHC, ICC, FC, FA, FUNC and most other immunological methods.
Product Property
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "HTT"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B023(A) | Recombinant Anti-human HTT Intrabody [(D-Arg)9] | ELISA, WB, ICC, FuncS | scFv-(D-Arg)9 |
| IAB-B023(G) | Recombinant Anti-human HTT Intrabody [+36 GFP] | IF, FC, WB, FuncS | scFv-(+36GFP) |
| IAB-B023(T) | Recombinant Anti-human HTT Intrabody [Tat] | WB, CO-IP, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-521 | Recombinant Human Anti-human HTT Antibody | WB, Neut, FuncS | IgG |
| HPAB-0123-YC | Mouse Anti-HTT Recombinant Antibody (HPAB-0123-YC) | IHC, WB, Inhib | Mouse IgG2a |
| HPAB-0125-YC | Human Anti-HTT Recombinant Antibody (HPAB-0125-YC) | ELISA, IHC | Humanized IgG |
| HPAB-0126-YC | Human Anti-HTT Recombinant Antibody (HPAB-0126-YC) | ELISA, IHC | Humanized IgG |
| MRO-0801-CN | Rabbit Anti-HTT Recombinant Antibody (clone JB89-34) | WB, IHC, FC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-521-S(P) | Recombinant Human Anti-human HTT Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| HPAB-0121-YC-S(P) | Mouse Anti-HTT Recombinant Antibody (clone MW1); scFv Fragment | ELISA, FC, WB, IHC | Mouse scFv |
| HPAB-0122-YC-S(P) | Mouse Anti-HTT Recombinant Antibody; scFv Fragment (HPAB-0122-YC-S(P)) | ELISA, FC, WB, IHC | Mouse scFv |
| HPAB-0123-YC-S(P) | Mouse Anti-HTT Recombinant Antibody; scFv Fragment (HPAB-0123-YC-S(P)) | ELISA, FC, WB, IHC | Mouse scFv |
| HPAB-0125-YC-S(P) | Human Anti-HTT Recombinant Antibody; scFv Fragment (HPAB-0125-YC-S(P)) | ELISA, IHC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-114CT | Human Anti-HTT Recombinant Antibody (TAB-114CT) | ELISA, WB | Human IgG1, κ |
| TAB-114CT-F(E) | Human Anti-HTT Recombinant Antibody; Fab Fragment (TAB-114CT-F(E)) | ELISA, WB | Human Fab |
| PABX-109 | Recombinant Human Anti-Huntingtin (Htt) Antibody | WB, Neut, FuncS | IgG |
| PABX-108-S (P) | Recombinant Mouse Anti-Huntingtin Antibody scFv Fragment (PABX-108-S (P)) | WB, ELISA, FuncS | scFv |
| PABX-109-F (E) | Recombinant Human Anti-Huntingtin(Htt) Antibody Fab Fragment | WB, Neut, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-115CT-S(P) | Mouse Anti-HTT Recombinant Antibody; scFv Fragment (TAB-115CT-S(P)) | ELISA, WB | Mouse scFv |
| TAB-116CT-S(P) | Mouse Anti-HTT Recombinant Antibody; scFv Fragment (TAB-116CT-S(P)) | ELISA, WB | Mouse scFv |
| TAB-117CT-S(P) | Mouse Anti-HTT Recombinant Antibody; scFv Fragment (TAB-117CT-S(P)) | ELISA, WB | Mouse scFv |
| PABX-108 | Recombinant Mouse Anti-Huntingtin Antibody (PABX-108) | WB, ELISA, FuncS | IgG |
| PABX-108-F (E) | Recombinant Mouse Anti-Huntingtin(Htt) Antibody Fab Fragment (PABX-108-F (E)) | WB, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1714 | Rabbit Anti-HTT Recombinant Antibody (clone DS1714AB) | WB, IHC-P, ICC | Rabbit IgG |
| MOR-0066-FY | Rabbit Anti-HTT Recombinant Antibody (clone AFY0037) | FC, ICC, IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0122-YC | Mouse Anti-HTT Recombinant Antibody (HPAB-0122-YC) | FuncS, WB, Inhib, IHC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0121-YC-F(E) | Mouse Anti-HTT Recombinant Antibody (clone MW1); Fab Fragment | ELISA, FC, WB, IHC | Mouse Fab |
| HPAB-0122-YC-F(E) | Mouse Anti-HTT Recombinant Antibody; Fab Fragment (HPAB-0122-YC-F(E)) | ELISA, FC, WB, IHC | Mouse Fab |
| HPAB-0123-YC-F(E) | Mouse Anti-HTT Recombinant Antibody; Fab Fragment (HPAB-0123-YC-F(E)) | ELISA, FC, WB, IHC | Mouse Fab |
| HPAB-0125-YC-F(E) | Human Anti-HTT Recombinant Antibody; Fab Fragment (HPAB-0125-YC-F(E)) | ELISA, IHC | Humanized Fab |
| HPAB-0126-YC-F(E) | Human Anti-HTT Recombinant Antibody; Fab Fragment (HPAB-0126-YC-F(E)) | ELISA, IHC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-039CN | Human Anti-HTT Recombinant Antibody (NS-039CN) | ELISA, DB, IHC, FuncS | Human IgG |
| NS-039CN-F(E) | Human Anti-HTT Recombinant Antibody; Fab Fragment (NS-039CN-F(E)) | ELISA | Human Fab |
| NS-039CN-S(P) | Human Anti-HTT Recombinant Antibody; scFv Fragment (NS-039CN-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABJ-0201 | Human Anti-HTT Recombinant Antibody (PABJ-0201) | ELISA, FuncS | Human VL |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1080 | Anti-HTT Immunohistochemistry Kit | IHC | |
| VS-0525-XY3360 | Anti-Mouse HTT Immunohistochemistry Kit | IHC | |
| VS-0525-XY3359 | Anti-Human HTT Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC384 | Recombinant Anti-HTT Vesicular Antibody, EV Displayed (VS-0425-YC384) | ELISA, FC, Neut, Cell-uptake |
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