Can you describe the versatility of applications for the CCR5 antibody?

Our CCR5 antibody is validated for a wide range of applications including IF, IP, ELISA, FC, and neutral assays. This versatility makes it an excellent tool for research focused on human CCR5 expression on T lymphocytes, ensuring reliable performance across multiple experimental setups.

How does the humanized design contribute to its experimental consistency?

The antibody is humanized from a mouse source and expressed in CHO cells, which enhances both its specificity and reproducibility. With purity above 95% by SDS-PAGE, it provides clear and consistent results across various assays such as ELISA, IF, and IP, ideal for detailed receptor studies.

Anti-Human CCR5 Recombinant Antibody

CAT#: TAB-10000S

Recombinant humanized (from mouse) antibody expressed in CHO binding to human CCR5. Anti-Human CCR5 Therapeutic Antibody is a humanized monoclonal antibody targeted against the CCR5 receptor found on T lymphocytes of the human immune system. It is being investigated as a potential therapy in the treatment of HIV infection.

Gene Expression

RNA Expression Figure 1 RNA cell line category: Cell line enhanced (JURKAT, Karpas-707, U-266/84)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160791-CCR5

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Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Mouse

Derivation
Humanized (from mouse)

Type
IgG4

Species Reactivity
Human

Applications
Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.

Product Property

Purity
>95.0% as determined by analysis by SDS-PAGE.

Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

Alternative Names
CCR5;chemokine (C-C motif) receptor 5 (gene/pseudogene);chemokine (C C motif) receptor 5 , CMKBR5;C-C chemokine receptor type 5;CC CKR 5;CD195;CKR 5;CKR5;IDDM22;chemr13;HIV-1 fusion coreceptor;chemokine receptor CCR5;C-C motif chemokine receptor 5

Gene ID
1234

UniProt ID
P51681

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Breast cancer biomarkers at key points during disease progression

Valuable for Studies

I used the humanized CCR5 antibody in immunofluorescence and immunoprecipitation assays. The antibody offered excellent specificity in detecting CCR5 on T lymphocytes. The extensive quality data and high purity information were very useful for optimizing assay conditions in my research.

Impressive Specificity

The anti-CCR5 antibody delivered consistent performance in experiments such as ELISA and neutral assays. Its humanized design from mouse and expression in CHO cells ensured high specificity and minimal background. I was pleased with the reproducibility and detailed documentation provided for research applications.

Q&As

Can you describe the versatility of applications for the CCR5 antibody?

A: Our CCR5 antibody is validated for a wide range of applications including IF, IP, ELISA, FC, and neutral assays. This versatility makes it an excellent tool for research focused on human CCR5 expression on T lymphocytes, ensuring reliable performance across multiple experimental setups.
How does the humanized design contribute to its experimental consistency?

A: The antibody is humanized from a mouse source and expressed in CHO cells, which enhances both its specificity and reproducibility. With purity above 95% by SDS-PAGE, it provides clear and consistent results across various assays such as ELISA, IF, and IP, ideal for detailed receptor studies.

View the frequently asked questions answered by Creative Biolabs Support.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-10000S, RRID: AB_3111805)

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-10000S.pdf

MSDS

MSDS - TAB-10000S.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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