Recombinant Mouse anti-Human HMGB1 Monoclonal antibody (19N10B7)
CAT#: MOB-0839CT
Recombinant Mouse monoclonal antibody to Human HMGB1, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RH-30
Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73663/2043_F12_32_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5873/617_A1_1_selected.jpg
Subcellular Location
Figure 3 IHC staining of human bone marrow
Immunohistochemical staining of human bone marrow shows strong nuclear positivity in hematopoietic cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_B_4_4_selected.jpg
Subcellular Location
Figure 4 IHC staining of human esophagus
Immunohistochemical staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5873/ihc_selected.jpg
Subcellular Location
Figure 5 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5873/613_A1_1_red_green.jpg
Subcellular Location
Figure 6 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5873/610_A1_1_red_green.jpg
Normal Tissue
Figure 7 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_B_8_5.jpg
Normal Tissue
Figure 8 Colon
Endocrine cells
Staining: High
Intensity: Strong
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_A_9_3.jpg
Normal Tissue
Figure 9 Liver
Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_A_8_4.jpg
Normal Tissue
Figure 10 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_A_7_5.jpg
Normal Tissue
Figure 11 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_A_8_8.jpg
RNA Expression
Figure 12 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000189403-HMGB1
❮
❯
Specifications
- Immunogen
- This immunogen is full-length recombinant human HMGB1 protein, encompassing amino acids 1 to 216, fused with a tag.
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- 19N10B7
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Flow Cytometry; Immunocytochemistry/Immunofluorescence; Immunohistochemistry paraffin embedded sections; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein A purified
- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Preservative: None Constituents: 1X PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- HMGB1; high mobility group box 1; HMG1; HMG3; SBP-1; high mobility group protein B1; HMG-1; Amphoterin; high-mobility group box 1; high mobility group protein 1; Sulfoglucuronyl carbohydrate binding protein; high-mobility group (nonhistone chromosomal) protein 1;
- Gene ID
- 3146
- UniProt ID
- P09429
- Protein Refseq
- NP_002119
- Function
- DNA bending activity; DNA bending activity; DNA binding; RAGE receptor binding; calcium-dependent protein kinase regulator activity; chemoattractant activity; cytokine activity; cytokine activity; damaged DNA binding; double-stranded DNA binding; protein
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for MOB-0839CT. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "HMGB1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-956 | Human Anti-HMGB1 Recombinant Antibody (clone Giby-1-4) | ELISA, WB | Human IgG |
| DrMAB-957 | Human Anti-HMGB1 Recombinant Antibody (clone Giby-1-4), Biotin | ELISA, WB | Human IgG |
| MRO-0755-CN | Rabbit Anti-HMGB1 Recombinant Antibody (clone CBACN-279) | WB, IF, IHC, FC | Rabbit IgG |
| MRO-1938-CN | Rabbit Anti-HMGB1 Polyclonal Antibody (MRO-1938-CN) | WB, IF, IHC, FC | Rabbit IgG |
| MRO-1939-CN | Rabbit Anti-HMGB1 Polyclonal Antibody (MRO-1939-CN) | WB, IF, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0315CL | Mouse Anti-HMGB1 Recombinant Antibody (TAB-0315CL) | IHC | Mouse IgG |
| TAB-0316CL | Mouse Anti-HMGB1 Recombinant Antibody (TAB-0316CL) | ELISA, Inhib, FuncS, WB | Mouse IgG |
| TAB-0317CL | Mouse Anti-HMGB1 Recombinant Antibody (TAB-0317CL) | ELISA, Inhib, FuncS, WB | Mouse IgG |
| TAB-0318CL | Mouse Anti-HMGB1 Recombinant Antibody (TAB-0318CL) | ELISA, Inhib, FuncS, WB | Mouse IgG |
| TAB-0315CL-S(P) | Mouse Anti-HMGB1 Recombinant Antibody; scFv Fragment (TAB-0315CL-S(P)) | ELISA, Inhib, FuncS, WB | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-099CT | Human Anti-HMGB1 Recombinant Antibody (TAB-099CT) | IF, ELISA, IHC | Human IgG1, λ |
| TAB-099CT-S(P) | Human Anti-HMGB1 Recombinant Antibody; scFv Fragment (TAB-099CT-S(P)) | ELISA, FC, Block | Human scFv |
| TAB-099CT-F(E) | Human Anti-HMGB1 Recombinant Antibody; Fab Fragment (TAB-099CT-F(E)) | ELISA, FC, Block | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-101CT | Anti-Human HMG1 Recombinant Antibody | ELISA, BL | Human antibody |
| TAB-101CT-S(P) | Anti-Human HMG1 Recombinant Antibody scFv Fragment | ELISA, BL | Human antibody |
| TAB-101CT-F(E) | Anti-Human HMG1 Recombinant Antibody Fab Fragment | ELISA, BL | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1633 | Rabbit Anti-HMGB1 Recombinant Antibody (clone DS1633AB) | WB, IHC-P, FC | Rabbit IgG |
| MOR-0049-FY | Rabbit Anti-HMGB1 Recombinant Antibody (clone AFY0020) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC2082 | PE-B*07:02/Human HMGB1 (APKRPPSAF) MHC Tetramer | FCM | |
| MHC-LC2083 | APC-B*07:02/Human HMGB1 (APKRPPSAF) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0215-FY-S(P) | Mouse Anti-HMGB1 Recombinant Antibody (clone 3E8); scFv Fragment | ELISA | Mouse scFv |
| HPAB-N0137-YC-S(P) | Mouse Anti-HMGB1 Recombinant Antibody; scFv Fragment (HPAB-N0137-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-0101-WJ-S(P) | Human Anti-HMGB1 Recombinant Antibody; scFv Fragment (HPAB-0101-WJ-S(P)) | ELISA, WB | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0215-FY-F(E) | Mouse Anti-HMGB1 Recombinant Antibody (clone 3E8); Fab Fragment | ELISA | Mouse Fab |
| HPAB-N0137-YC-F(E) | Mouse Anti-HMGB1 Recombinant Antibody; Fab Fragment (HPAB-N0137-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-0101-WJ-F(E) | Human Anti-HMGB1 Recombinant Antibody; Fab Fragment (HPAB-0101-WJ-F(E)) | ELISA, WB | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1654 | Recombinant Mouse Anti-HMGB1 Capture Antibody (clone 1B5) | ELISA | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC699 | AbPlus™ Anti-HMGB1 Magnetic Beads (VS-0724-YC699) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1033 | Anti-HMGB1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3204 | Anti-Mouse HMGB1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3206 | Anti-Human HMGB1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3205 | Anti-Rat HMGB1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC535 | CytoStream™ Rabbit Anti-HMGB1 Recombinant Antibody (VS13-YC535) | WB, ICC, IF, IHC-P, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC143 | Recombinant Anti-HMGB1 Eliminating Antibody, pH-Sensitive (VS-0625-YC143) | Antigen-Sweeping In Vivo. | Human IgG1 lambda |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: ELISA, WB, BLI, SPR
Application:
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
